Methylation Clinical Trials

11 recruitingLast updated: June 18, 2026

There are 11 actively recruiting methylation clinical trials across 5 countries. Studies span Not Applicable, Phase 3. Top locations include Shanghai, Shanghai Municipality, China, Chūō, Yamanashi, Japan, Beijing, Beijing Municipality, China. Updated daily from ClinicalTrials.gov.


Methylation Trials at a Glance

11 actively recruiting trials for methylation are listed on ClinicalTrialsFinder across 6 cities in 5 countries. The largest study group is Not Applicable with 3 trials, with the heaviest enrollment activity in Shanghai, Chūō, and Beijing. Lead sponsors running methylation studies include City of Hope Medical Center, Fudan University, and Lei Li.

Browse methylation trials by phase

Treatments under study

About Methylation Clinical Trials

Looking for clinical trials for Methylation? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Methylation trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Methylation clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 111 of 11 trials

Recruiting
Not Applicable

Methylated Biomarkers of Smoking as a Selection Tool in Participants for Lung Cancer Screening

Lung Cancer ScreeningEpigeneticsDNA Methylation+2 more
University Hospital, Antwerp1,000 enrolled1 locationNCT07631624
Recruiting

Maternal Methyl-Nutrient Status and Infant Neurodevelopment Study

PregnancyNutritionDietary Quality+6 more
Far Eastern Memorial Hospital240 enrolled2 locationsNCT07568561
Recruiting
Not Applicable

Epigenetic Biomarkers in the Saliva for the Diagnosis of Squamous Cells Carcinoma of the Oral Cavity

BiomarkersOral Squamous Cell CarcinomaEpigenetics+3 more
Centre Hospitalier Universitaire, Amiens60 enrolled1 locationNCT05791149
Recruiting

PaCIFiC-CUP Classifies Cancer of Unknown Primary

Unknown Primary TumorsDNA Methylation
Sun Yat-sen University120 enrolled1 locationNCT06140992
Recruiting
Not Applicable

Circulating Tumor DNA Methylation Guided Postoperative Follow-up Strategy for Non-metastatic Colorectal Cancer

Circulating Tumor DNA MethylationNon Metastatic Colorectal Cancer
Fudan University584 enrolled1 locationNCT05904665
Recruiting

Predicting Early Tumor Recurrence in Patients With Esophageal Squamous Cell Carcinoma

Esophageal CancerRecurrenceDNA Methylation
City of Hope Medical Center150 enrolled2 locationsNCT06476067
Recruiting

Predicting Postoperative Chemotherapy Efficacy in Patients With Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell CarcinomaChemotherapy EffectDNA Methylation
City of Hope Medical Center150 enrolled1 locationNCT06490003
Recruiting

Construction of Molecular Diagnostic Marker Model for Pancreatic Cystic Tumors Based on Pancreatic Cystic Fluid Samples

Pancreatic NeoplasmsDNA MethylationProteome
Zhaoshen Li100 enrolled1 locationNCT05737953
Recruiting
Phase 3

Circulating Tumor DNA Methylation Guided Postoperative Adjuvant Chemotherapy for High-risk Stage II/III Colorectal Cancer

High-risk Stage II Colorectal CancerStage III Colorectal CancerCirculating Tumor DNA Methylation
Fudan University340 enrolled1 locationNCT05954078
Recruiting

ctDNA Methylation for Epithelial Ovarian Cancer

Circulating Tumor DNAEpithelial Ovarian CancerDNA Methylation+5 more
Lei Li5,000 enrolled1 locationNCT05801263
Recruiting

ctDNA Methylation for Detecting Ovarian Cancer

Circulating Tumor DNAEpithelial Ovarian CancerDNA Methylation+6 more
Lei Li1,400 enrolled1 locationNCT05801276