Phase 2 MGMT-Unmethylated Glioblastoma Clinical Trials

3 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 1–3 of 3 trials

Recruiting

Phase 1Phase 2

DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma

MGMT-Unmethylated GlioblastomaHigh Grade GliomaMGMT-Methylated Glioblastoma

University of California, San Francisco70 enrolled5 locationsNCT06504381

Recruiting

Phase 2

Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma

Brain CancerGlioblastomaGlioblastoma Multiforme+4 more

Baptist Health South Florida190 enrolled1 locationNCT06991101

Recruiting

Phase 2

Crizanlizumab Alone or in Combination With Nivolumab for Glioblastoma and Melanoma With Brain Metastases

Advanced GlioblastomaMetastatic Melanoma in the Central Nervous SystemMGMT-Unmethylated Glioblastoma

Sheba Medical Center33 enrolled1 locationNCT05909618