Phase 1 Mitochondrial disease Clinical Trials
6 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–6 of 6 trials
Recruiting
Phase 1
Validation of Oxygen Nanosensor in Mitochondrial Myopathy
Mitochondrial DiseasesMItochondrial Myopathies
Children's Hospital of Philadelphia24 enrolled1 locationNCT04086329
Recruiting
Phase 1
Validation of Nanosensor Oxygen Measurement
Mitochondrial diseaseMItochondrial Myopathies
Children's Hospital of Philadelphia96 enrolled1 locationNCT06819683
Recruiting
Phase 1
Study of N-acetylcysteine in the Treatment of Patients With the m.3243A>G Mutation and Low Brain Glutathione Levels
Mitochondrial disease
Michio Hirano, MD18 enrolled1 locationNCT05241262
Recruiting
Phase 1
Applying pGz in Mitochondrial Disease
Mitochondrial DiseasesMItochondrial Myopathies
Children's Hospital of Philadelphia90 enrolled1 locationNCT05569122
Not Yet Recruiting
Phase 1
A Phase 1 Randomized, Double-Blind, Placebo-Controlled Study With A Food Effect Assessment To Evaluate The Safety, Tolerability, And Pharmacokinetics Of Single Ascending Doses And Multiple Ascending Doses Of PX578 In Healthy Adult Participants (Part C)
Mitochondrial disease
Pretzel Therapeutics Inc.24 enrolled1 locationACTRN12625000452493
Recruiting
Phase 1
A Phase 1 Randomized, Double-Blind, Placebo-Controlled Study With A Food Effect Assessment To Evaluate The Safety, Tolerability, And Pharmacokinetics Of Single Ascending Doses And Multiple Ascending Doses Of PX578 In Healthy Adult Participants (Part A & B)
Mitochondrial disease
Pretzel Therapeutics Inc.112 enrolled1 locationACTRN12625000230459