Multimorbidity Clinical Trials

12 recruitingLast updated: June 18, 2026

There are 12 actively recruiting multimorbidity clinical trials across 9 countries. Studies span Not Applicable, Phase 1, Phase 2. Top locations include Basel, Switzerland, Boston, Massachusetts, United States, Changsha, China. Updated daily from ClinicalTrials.gov.


Multimorbidity Trials at a Glance

12 actively recruiting trials for multimorbidity are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Not Applicable with 8 trials, with the heaviest enrollment activity in Basel, Boston, and Changsha. Lead sponsors running multimorbidity studies include Malin Olsen Syversen, Martin-Luther-Universität Halle-Wittenberg, and KU Leuven.

Browse multimorbidity trials by phase

Treatments under study

About Multimorbidity Clinical Trials

Looking for clinical trials for Multimorbidity? There are currently 18 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Multimorbidity trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Multimorbidity clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting
Phase 1Phase 2

Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With Multimorbidity

HealthyMultimorbidity
Ove Andersen60 enrolled1 locationNCT06431932
Recruiting
Not Applicable

Health Chat for Empowerment-based Lifestyle Planning for Cardiometabolic Multimorbidity

Cardiometabolic DiseasesMultimorbidity
The University of Hong Kong232 enrolled3 locationsNCT07158697
Recruiting
Not Applicable

Optimizing Prescribing Decisions for Hospitalized Older Adults With Chronic Conditions

HypertensionDiabetesPrescribing Decisions+2 more
University of Pittsburgh150 enrolled1 locationNCT06605807
Recruiting
Not Applicable

Multicomponent Telerehabilitation to Engage Veterans in Effective Self-Management of Complex Health Conditions

physical deconditioningMultimorbidity
VA Office of Research and Development126 enrolled1 locationNCT06288438
Recruiting
Not Applicable

Annual Wellness Visits vs GRACE-augmented Annual Wellness Visits For Older Adults With High Needs - Phase 2

Preventive careAgingPalliative Care+1 more
Massachusetts General Hospital6,080 enrolled4 locationsNCT07166861
Recruiting
Not Applicable

Integrated Care for Older Adults With Major Depression and Physical Multimorbidity - The I-CONNECT

Depression - Major Depressive DisorderOlder Adults (65 Years and Older)Mood Disorders+3 more
KU Leuven82 enrolled1 locationNCT07211750
Recruiting

Multimorbidity and Cardiovascular Risk Factors After Renal Transplant

Cardiovascular (CV) RiskKidney TransplantMultimorbidity
University Hospitals of Derby and Burton NHS Foundation Trust30 enrolled1 locationNCT07205692
Recruiting
Not Applicable

Association of a Digital Signature of Physical Activity and Sedentary Lifestyle With the Development of Multimorbidities in Chronic Diseases (eMOB)

ExerciseComorbidities and Coexisting ConditionsSedentary Behavior+4 more
University Hospital, Clermont-Ferrand700 enrolled1 locationNCT05578495
Recruiting

Sleep Disordered Breathing and Multimorbidity: The Xiangya SDB Cohort Study

Sleep-disordered breathing (SDB)Sleep ApneaCardiometabolic Diseases+2 more
Xiangya Hospital of Central South University15,000 enrolled1 locationNCT06755840
Recruiting
Not Applicable

Reduction of Polypharmacy in Elderly People With Multiple Diseases

PolypharmacyMultimorbidity
Martin-Luther-Universität Halle-Wittenberg1,146 enrolled1 locationNCT05526963
Recruiting

Co-design of a Seamless Person-centered Intervention to Optimize Medication Use Across Healthcare Levels

Multimorbidity
Malin Olsen Syversen240 enrolled1 locationNCT05421143
Recruiting
Not Applicable

AdvantAGE: Implementation and Evaluation of an Interprofessional Tranistional Care Model for Frail Older Adults

Transitional CareMultimorbidityGeriatric Care
Thekla Brunkert250 enrolled1 locationNCT06190288