Phase 1 Multiple System Atrophy Clinical Trials
10 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–10 of 10 trials
Recruiting
Phase 1
Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ION464 Administered to Adults With Multiple System Atrophy (HORIZON)
Multiple System Atrophy
Ionis Pharmaceuticals, Inc.40 enrolled15 locationsNCT04165486
Recruiting
Phase 1
A Phase I/III Clinical Study to Evaluate NouvNeu001 Injection for Multiple System Atrophy
Multiple System Atrophy - Parkinsonian Subtype (MSA-P)
iRegene Therapeutics Co., Ltd.9 enrolled1 locationNCT07289477
Recruiting
Phase 1
Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies
Multiple System AtrophyParkinsons Disease
Craig van Horne, MD, PhD7 enrolled1 locationNCT06683365
Not Yet Recruiting
Phase 1
A Study to Assess the Effect of Acid-Reducing Medicines on ATH434 in Healthy Volunteers
Multiple System Atrophy (MSA)
Alterity Therapeutics Limited12 enrolled1 locationACTRN12626000320358
Recruiting
Phase 1
[18F]F-DOPA Imaging in Patients With Autonomic Failure
Multiple System AtrophyParkinson DiseaseDementia With Lewy Bodies+2 more
Daniel Claassen40 enrolled1 locationNCT04246437
Recruiting
Phase 1
Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure
Multiple System AtrophyAutonomic FailurePure Autonomic Failure+1 more
Vanderbilt University Medical Center29 enrolled1 locationNCT02429557
Recruiting
Phase 1Phase 2
Automated Abdominal Binder for Orthostatic Hypotension
Multiple System AtrophyAutonomic FailurePure Autonomic Failure+1 more
Vanderbilt University Medical Center31 enrolled1 locationNCT03482297
Recruiting
Phase 1
Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure
Multiple System AtrophyParkinson DiseaseAutonomic Failure+2 more
Vanderbilt University Medical Center34 enrolled1 locationNCT02897063
Recruiting
Phase 1
A Phase 1 single and multiple ascending dose study of YA-101 in Healthy Subjects
Multiple System Atrophy
Yoda Pharmaceuticals Aus Pty Ltd60 enrolled1 locationACTRN12623001117606
Completed
Phase 1
A Phase 1 Study to Evaluate a Tablet Formulation of PBT434 in Healthy Volunteers
Multiple System Atrophy
Alterity Therapeutics Limited42 enrolled2 locationsACTRN12620001244998