Muscle Clinical Trials

5 recruiting

Frequently Asked Questions

Common questions about Muscle clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 334 trials

Recruiting
Phase 2

Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial

Muscle Invasive Bladder Urothelial CarcinomaStage II Bladder Cancer AJCC v8Stage IIIA Bladder Cancer AJCC v8
National Cancer Institute (NCI)111 enrolled127 locationsNCT07061964
Recruiting
Phase 2

A Study to Evaluate the Efficacy and Safety of Autogene Cevumeran With Nivolumab Versus Nivolumab Alone in Participants With High-risk Muscle-invasive Urothelial Carcinoma (MIUC)

Muscle-invasive Urothelial Carcinoma
Hoffmann-La Roche362 enrolled107 locationsNCT06534983
Recruiting

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

Head and Neck CarcinomaMalignant Solid NeoplasmSarcoma+59 more
Alliance for Clinical Trials in Oncology2,000 enrolled740 locationsNCT05334069
Recruiting
Phase 2

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Stage I Bladder Cancer AJCC v8Non-Muscle Invasive Bladder Urothelial CarcinomaRecurrent Non-Muscle Invasive Bladder Urothelial Carcinoma
National Cancer Institute (NCI)160 enrolled120 locationsNCT06770582
Recruiting

Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults

Muscle WeaknessProblems Moving Their Arms and Legs
National Institutes of Health Clinical Center (CC)23 enrolled1 locationNCT06998134
Recruiting
Not Applicable

The Effect of Urolithin A (Mitopure®) Supplementation on Muscle Strength in Healthy Middle-Aged Adults

Muscle FunctionHealthy Aging
Amazentis SA120 enrolled1 locationNCT07231783
Recruiting
Not Applicable

Respiratory Muscles and Work of Breathing in Children

Lung DiseasesNeuromuscular DiseasesScoliosis+4 more
Assistance Publique - Hôpitaux de Paris550 enrolled1 locationNCT05051254
Recruiting
Not Applicable

Inspiratory Muscle Training in Lung Transplant Candidates

Inspiratory Muscle Training
University Health Network, Toronto90 enrolled4 locationsNCT06370832
Recruiting
Phase 3

Trial of Nadofaragene Firadenovec vs. Observation in Participants With Intermediate Risk Non-Muscle Invasive Bladder Cancer

Intermediate Risk Non-Muscle Invasive Bladder Cancer
Ferring Pharmaceuticals454 enrolled79 locationsNCT06510374
Recruiting
Not Applicable

Dose-Response Impact of Geranylgeraniol (GG) Supplementation on Muscle Health

Body CompositionMuscle StrengthMuscle Health
Lindenwood University70 enrolled1 locationNCT07502924
Recruiting
Phase 1Phase 2

In-home Intravesical Chemotherapy for the Treatment of Bladder Cancer, INVITE Trial

Non-Muscle Invasive Bladder CarcinomaStage 0a Bladder Cancer AJCC v8Stage 0is Bladder Cancer AJCC v8+1 more
Mayo Clinic40 enrolled1 locationNCT06704191
Recruiting
Not Applicable

Dynamic Neuromuscular Stabilization vs Pelvic Floor Muscle Training in Women With Stress Urinary Incontinence

Quality of LifePelvic Floor Muscle TrainingStress Urinary Incontinence (SUI)+3 more
Izmir Katip Celebi University51 enrolled1 locationNCT07075900
Recruiting
Not Applicable

Pneumatic Compression vs Blood Flow Restriction for Muscle Recovery

Delayed Onset Muscle Soreness
University of Southern California33 enrolled1 locationNCT06815367
Recruiting
Not Applicable

Function and Lean Mass Preservation With Resistance Exercise During a GLP-1RA Treatment

Muscle Mass and Strength
University of Exeter60 enrolled1 locationNCT07457437
Recruiting
Not Applicable

Training Models in Pelvic Floor Muscle Training

Pelvic Floor Muscle TrainingPelvic Floor Muscle ExerciseHealthy Adult Women
Izmir University of Economics60 enrolled1 locationNCT07099170
Recruiting
Not Applicable

Neuromuscular Electrical Stimulation in a Patient on Invasive Mechanical Ventilation (MOVCARE)

Mechanical VentilationCritical IllnessNeuromuscular Electrical Stimulation (NMES)+2 more
Hospital Moinhos de Vento150 enrolled1 locationNCT07188350
Recruiting
Phase 2

A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)

Urinary Bladder NeoplasmsNon-Muscle Invasive Bladder Neoplasms
Merck Sharp & Dohme LLC308 enrolled89 locationsNCT06833073
Recruiting
Phase 2Phase 3

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Muscle Invasive Bladder Urothelial CarcinomaStage IV Bladder Urothelial Carcinoma AJCC v7Muscle Invasive Renal Pelvis Urothelial Carcinoma+4 more
National Cancer Institute (NCI)992 enrolled491 locationsNCT05987241
Recruiting
Not Applicable

Transcutaneous Electrical Nerve Stimulation (TENS) for the Treatment of Low Back Pain (LBP) in Adults

Low Back PainCLBP - Chronic Low Back PainParaspinal Muscles
Xijing Hospital40 enrolled1 locationNCT07368920
Recruiting
Phase 1

Sodium Aescinate for the Treatment of Low Back Pain (LBP) in Adults

Non-specific Chronic Low Back PainLow Back PainParaspinal Muscle+1 more
Xijing Hospital40 enrolled1 locationNCT07339631