Muscle Clinical Trials

444 recruitingLast updated: May 21, 2026

There are 444 actively recruiting muscle clinical trials across 57 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4, Early Phase 1. Top locations include New York, New York, United States, Boston, Massachusetts, United States, Los Angeles, California, United States. Updated daily from ClinicalTrials.gov.


Muscle Trials at a Glance

444 actively recruiting trials for muscle are listed on ClinicalTrialsFinder across 6 cities in 57 countries. The largest study group is Not Applicable with 221 trials, with the heaviest enrollment activity in New York, Boston, and Los Angeles. Lead sponsors running muscle studies include Riphah International University, Cairo University, and Assiut University.

About Muscle Clinical Trials

Looking for clinical trials for Muscle? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Muscle trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Muscle clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 444 trials

Recruiting
Phase 2Phase 3

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Muscle Invasive Bladder Urothelial CarcinomaStage IV Bladder Urothelial Carcinoma AJCC v7Muscle Invasive Renal Pelvis Urothelial Carcinoma+4 more
National Cancer Institute (NCI)992 enrolled495 locationsNCT05987241
Recruiting

Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults

Muscle WeaknessProblems Moving Their Arms and Legs
National Institutes of Health Clinical Center (CC)23 enrolled1 locationNCT06998134
Recruiting
Phase 2

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Stage I Bladder Cancer AJCC v8Non-Muscle Invasive Bladder Urothelial CarcinomaRecurrent Non-Muscle Invasive Bladder Urothelial Carcinoma
National Cancer Institute (NCI)160 enrolled129 locationsNCT06770582
Recruiting
Not Applicable

Biofeedback-Assisted Pelvic Floor Rehabilitation for Radiation-Induced Sexual Dysfunction in Cervical Cancer Survivors

Cervical CancerFemale Sexual Dysfunction (FSD)Radiation Induced Pelvic Floor Muscle Dysfunction
Beni-Suef University60 enrolled1 locationNCT07597083
Recruiting
Phase 2

Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial

Muscle Invasive Bladder Urothelial CarcinomaStage II Bladder Cancer AJCC v8Stage IIIA Bladder Cancer AJCC v8
National Cancer Institute (NCI)111 enrolled141 locationsNCT07061964
Recruiting
Not Applicable

MyokinE100 System: Closed Loop Electrical Muscle Stimulation to Mitigate ICU Acquired Weakness in Medical ICU Patients

ICU acquired weaknessSarcopeniaSepsis+4 more
Health Discovery Labs50 enrolled3 locationsNCT07362862
Recruiting
Not Applicable

Impact of NMES and HPRO on Recovery After SAH- Pilot Study

InflammationSubarachnoid HemorrhageMuscle Atrophy+1 more
University of Maryland, Baltimore30 enrolled1 locationNCT03201094
Recruiting
Phase 2

Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer

Non Muscle Invasive Bladder Cancer
Protara Therapeutics131 enrolled66 locationsNCT05951179
Recruiting
Not Applicable

Comparative Effects of Autogenic Inhibition and Reciprocal Inhibition Technique on Pain, Functional Disability and Gait in Sacroiliac Joint Dysfuction.

Sacroiliac Joint DysfunctionMuscle Energy Techniques
Foundation University Islamabad40 enrolled1 locationNCT07600359
Recruiting
Phase 2

A Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With Muscle-invasive Bladder Cancer Keep Their Bladder

Muscle Invasive Bladder Cancer
Astellas Pharma Global Development, Inc.240 enrolled5 locationsNCT07475806
Recruiting
Not Applicable

Imaging Skeletal Muscle Mitochondrial OXPHOS Activity In Acute Lymphoblastic Leukemia Survivors

Muscle WeaknessChildhood Cancer
St. Jude Children's Research Hospital60 enrolled1 locationNCT06819475
Recruiting
Phase 2

TCM Formula vs. HMB in Pre-Frail Elders: Muscle Strength and Bone Status

pre frailtySarcopeniaOsteoporosis+2 more
Tri-Service General Hospital90 enrolled1 locationNCT07597850
Recruiting
Not Applicable

Effects of High Intensity Laser Therapy in Muscle Injuries

Muscle Tear
Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari24 enrolled1 locationNCT06812611
Recruiting
Not Applicable

Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling

ObesityInsulin ResistanceMuscle Weakness+2 more
University of Colorado, Denver70 enrolled1 locationNCT06129110
Recruiting
Not Applicable

The RECOVER Study - Postpartum Recovery of Pelvic Floor Structures and the Impact of Early Rehabilitation

Pelvic organ prolapse (POP)Urinary IncontinencePelvic Floor Muscle Training+5 more
Vastra Gotaland Region380 enrolled2 locationsNCT07430865
Recruiting

Natural History of Inflammatory Muscle Diseases

Inflammation In Skeletal Muscle
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)500 enrolled1 locationNCT05738824
Recruiting
Not Applicable

This Study Investigates β-hydroxy-β-methylbutyrate (HMB) and 2-hydroxybenzylamine (2-HOBA), When Administered Either Individually or in Combination Contributes to an Increased Quality of Health, Specifically Improving Muscular Strength and Cognitive Functioning in Adults Over the Age of 65.

Cognitive functioningGeriatricageing+2 more
McGill University Health Centre/Research Institute of the McGill University Health Centre120 enrolled1 locationNCT07419633
Recruiting
Phase 3

Trial of Nadofaragene Firadenovec vs. Observation in Participants With Intermediate Risk Non-Muscle Invasive Bladder Cancer

Intermediate Risk Non-Muscle Invasive Bladder Cancer
Ferring Pharmaceuticals454 enrolled97 locationsNCT06510374
Recruiting
Phase 2

A Study to Evaluate the Efficacy and Safety of Autogene Cevumeran With Nivolumab Versus Nivolumab Alone in Participants With High-risk Muscle-invasive Urothelial Carcinoma (MIUC)

Muscle-invasive Urothelial Carcinoma
Hoffmann-La Roche362 enrolled107 locationsNCT06534983
Recruiting
Phase 3

A Study Comparing Standard Treatments in People With Non-Muscle Invasive Bladder Cancer (NMIBC)

Non Muscle Invasive Bladder Cancer
Memorial Sloan Kettering Cancer Center125 enrolled9 locationsNCT06929286