Phase 3 Muscle Clinical Trials
26 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 26 trials
Recruiting
Phase 2Phase 3
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study
Muscle Invasive Bladder Urothelial CarcinomaStage IV Bladder Urothelial Carcinoma AJCC v7Muscle Invasive Renal Pelvis Urothelial Carcinoma+4 more
National Cancer Institute (NCI)992 enrolled499 locationsNCT05987241
Recruiting
Phase 3
An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC
High-risk Muscle Invasive Urothelial Carcinoma
AstraZeneca915 enrolled160 locationsNCT07720284
Recruiting
Phase 3
Trial of Nadofaragene Firadenovec vs. Observation in Participants With Intermediate Risk Non-Muscle Invasive Bladder Cancer
Intermediate Risk Non-Muscle Invasive Bladder Cancer
Ferring Pharmaceuticals454 enrolled103 locationsNCT06510374
Recruiting
Phase 3
A Trial to Evaluate Intravesical Nadofaragene Firadenovec Alone or in Combination With Chemotherapy or Immunotherapy in Participants With High-grade BCG Unresponsive Non-muscle Invasive Bladder Cancer
Non-muscle Invasive Bladder Cancer With Carcinoma in Situ
Ferring Pharmaceuticals250 enrolled76 locationsNCT06545955
Recruiting
Phase 2Phase 3
Onabotulinum Toxin A (Botox) in the Treatment of Pharyngo-esophageal Dysphagia
Oropharyngeal DysphagiaTransfer DysphagiaCricopharyngeus Muscle Dysfunction
All India Institute of Medical Sciences100 enrolled1 locationNCT04695600
Recruiting
Phase 3
A Study to Evaluate TAR-210 Versus Intravesical Chemotherapy Treatment in Participants With High Risk Non-Muscle-Invasive Bladder Cancer
Non-Muscle Invasive Bladder Neoplasms
Janssen Research & Development, LLC220 enrolled110 locationsNCT06919965
Recruiting
Phase 3
A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer
Non-Muscle Invasive Bladder Neoplasms
Janssen Research & Development, LLC641 enrolled193 locationsNCT06319820
Recruiting
Phase 3
Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy
Stage 0a Bladder Cancer AJCC v8Stage I Bladder Cancer AJCC v8Recurrent Non-Muscle Invasive Bladder Carcinoma
Alliance for Clinical Trials in Oncology330 enrolled58 locationsNCT07000084
Recruiting
Phase 3
Efficacy and Safety of Intravesical TARA-002 Compared With Investigator's Choice of Intravesical Chemotherapy in Participants With BCG-naïve High-grade Non-muscle Invasive Bladder Cancer
Bladder (Urothelial, Transitional Cell) CancerNon-muscle Invasive Bladder Cancer With Carcinoma in SituNon-Muscle Invasive Bladder Carcinoma
Protara Therapeutics284 enrolled6 locationsNCT07480356
Recruiting
Phase 3
A Study Comparing Standard Treatments in People With Non-Muscle Invasive Bladder Cancer (NMIBC)
Non Muscle Invasive Bladder Cancer
Memorial Sloan Kettering Cancer Center125 enrolled9 locationsNCT06929286
Recruiting
Phase 3
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study
Muscle Invasive Bladder Urothelial CarcinomaStage II Bladder Cancer AJCC v8Stage IIIA Bladder Cancer AJCC v8
NRG Oncology486 enrolled211 locationsNCT07097142
Recruiting
Phase 3
Translaryngeal Vibration for Hyperfunctional Voice Disorders
DysphoniaMuscle Tension Dysphonia
Texas Christian University30 enrolled1 locationNCT07145086
Recruiting
Phase 2Phase 3
NEO-BLAST: Neoadjuvant Therapy for Bladder Cancer Followed by Active Surveillance vs Treatment
Muscle-Invasive Bladder Carcinoma
Peter Black688 enrolled1 locationNCT06537154
Recruiting
Phase 3
Treatment Expedition With MRI Processing and Optimization for Muscle Invasive Bladder Cancer
Bladder CarcinomaBladder NeoplasmMuscle Invasive Bladder Cancer (MIBC)+2 more
University of Rome Tor Vergata92 enrolled1 locationNCT07067749
Recruiting
Phase 2Phase 3
Therapeutic Photobiomodulation and Tretament of Spasticity
Muscle SpasticityCerebral PalsyPhotobiomodulation+1 more
University of Nove de Julho28 enrolled2 locationsNCT06536751
Recruiting
Phase 2Phase 3
Modular Trial of sEphB4-HSA in EphrinB2-High Solid Tumors
Metastatic Urothelial CarcinomaMuscle-Invasive Bladder Carcinoma
Vasgene Therapeutics, Inc700 enrolled1 locationNCT06493552
Recruiting
Phase 3
Investigating the Efficacy and Safety of Neoadjuvant Intravesical Instillation of Mitomycin C in Treating High-risk NMIBC Patients
Non-Muscle-Invasive Bladder Cancer (NMIBC)
Shaogang Wang180 enrolled3 locationsNCT06696794
Recruiting
Phase 2Phase 3
Effect of Magnesium Sulphate Pretreatment in Pediatric Abdominal Surgery
Muscle Relaxation
Assiut University58 enrolled2 locationsNCT05736744
Recruiting
Phase 2Phase 3
Effect of MgSO4 Pretreatment on Muscle Relaxation
Muscle Relaxation
Assiut University100 enrolled1 locationNCT05757999
Recruiting
Phase 2Phase 3
HMB and Exercise-induced Muscle Damage
SupplementationMuscle DamageRecovery+2 more
Poznan University of Physical Education30 enrolled1 locationNCT04549610