Muscle Clinical Trials in Boston, Massachusetts

21 recruitingBoston, Massachusetts

Showing 120 of 21 trials

Recruiting
Phase 2

Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial

Muscle Invasive Bladder Urothelial CarcinomaStage II Bladder Cancer AJCC v8Stage IIIA Bladder Cancer AJCC v8
National Cancer Institute (NCI)111 enrolled136 locationsNCT07061964
Recruiting
Phase 2

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Stage I Bladder Cancer AJCC v8Non-Muscle Invasive Bladder Urothelial CarcinomaRecurrent Non-Muscle Invasive Bladder Urothelial Carcinoma
National Cancer Institute (NCI)160 enrolled125 locationsNCT06770582
Recruiting
Phase 2Phase 3

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Muscle Invasive Bladder Urothelial CarcinomaStage IV Bladder Urothelial Carcinoma AJCC v7Muscle Invasive Renal Pelvis Urothelial Carcinoma+4 more
National Cancer Institute (NCI)992 enrolled494 locationsNCT05987241
Recruiting
Phase 3

A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer

Non-Muscle Invasive Bladder Neoplasms
Janssen Research & Development, LLC641 enrolled193 locationsNCT06319820
Recruiting
Phase 1Phase 2

LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

Non-muscle Invasive Bladder Cancer With Carcinoma in SituSuperficial Bladder Cancer
enGene, Inc.350 enrolled101 locationsNCT04752722
Recruiting
Phase 3

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

Muscle Invasive Bladder Urothelial CarcinomaStage II Bladder Cancer AJCC v8Stage IIIA Bladder Cancer AJCC v8
NRG Oncology486 enrolled211 locationsNCT07097142
Recruiting
Phase 3

Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy

Stage 0a Bladder Cancer AJCC v8Stage I Bladder Cancer AJCC v8Recurrent Non-Muscle Invasive Bladder Carcinoma
Alliance for Clinical Trials in Oncology330 enrolled56 locationsNCT07000084
Recruiting

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)

Movement DisordersMotor Neuron DiseaseHereditary Spastic Paraplegia+3 more
Boston Children's Hospital200 enrolled1 locationNCT05354622
Recruiting
Not Applicable

The Impact of Dry Needling on Electrophysiological and Ultrasound-based Biomarkers for Myofascial Pain

Trigger Point in Trapezius Muscle
Beth Israel Deaconess Medical Center70 enrolled2 locationsNCT07270276
Recruiting
Phase 1Phase 2

A Study of STM-416 Administered to Patients Undergoing TURBT for Recurrent Bladder Cancer

Non Muscle Invasive Bladder Cancer
SURGE Therapeutics75 enrolled10 locationsNCT05710848
Recruiting

Voice Therapy Per the Rehabilitation Treatment Specification System

Muscle Tension Dysphonia
Massachusetts General Hospital600 enrolled5 locationsNCT06152627
Recruiting

Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies

Facial PalsyCongenital Fibrosis of Extraocular MusclesDuane Retraction Syndrome+23 more
Boston Children's Hospital20,000 enrolled1 locationNCT03059420
Recruiting
Phase 2

Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer

Non Muscle Invasive Bladder Cancer
Protara Therapeutics131 enrolled61 locationsNCT05951179
Recruiting
Not Applicable

A SkeleTal Muscle Recovery Intervention With Dietary Protein in Heart Failure

Heart FailureMuscle Atrophy
Tufts Medical Center120 enrolled2 locationsNCT05627440
Recruiting

Imaging Genetics of Laryngeal Dystonia

Muscle Tension DysphoniaLaryngeal DystoniaUnaffected Relatives of Laryngeal Dystonia Patients+1 more
Kristina Simonyan410 enrolled1 locationNCT03042975
Recruiting
Phase 1

A Phase I Intravesical PPM Therapy for NMIBC

Non Muscle Invasive Bladder Cancer
VA Office of Research and Development29 enrolled1 locationNCT05519241
Recruiting
Early Phase 1

Project 4: Ambulatory Biofeedback and Voice Therapy for Patients With Vocal Hyperfunction

Voice disordersMuscle Tension DysphoniaVocal Fold Polyp+1 more
Massachusetts General Hospital100 enrolled2 locationsNCT05970562
Recruiting

A Retrospective and Prospective Natural History of Genetic Vasculopathies

Multisystemic Smooth Muscle Dysfunction SyndromeACTA2
Massachusetts General Hospital50 enrolled1 locationNCT06552052
Recruiting

Changes in Skeletal Muscle Thickness in Patients With Acute Heart Failure

Heart FailureCardiogenic ShockMuscle Atrophy+1 more
Tufts Medical Center60 enrolled1 locationNCT06253104
Recruiting
Not Applicable

PRotein Optimization With eXercise to Improve MUscle Mass and Functional outcomeS

Pediatric ALLMobilityMuscle Loss+1 more
Boston Children's Hospital72 enrolled2 locationsNCT05296096