Phase 1 Neoplasia Clinical Trials

9 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 19 of 9 trials

Recruiting
Phase 1

Lopinavir/Ritonavir in PLWH With High-Grade AIN

High-Grade Anal Intraepithelial Neoplasia
University of Wisconsin, Madison21 enrolled1 locationNCT05334004
Recruiting
Phase 1

First-in-Human Assessment of Safety, Biodistribution and Pharmacokinetics of 18F-Fluoro-1-Naphthol (18F-4FN) for PET Imaging

Endocrine Neoplasia
M.D. Anderson Cancer Center55 enrolled1 locationNCT05335811
Recruiting
Phase 1

Fenofibrate in Patients With Cervical Intraepithelial Neoplasia and Invasive Cervical Carcinoma

Cervical Intraepithelial NeoplasiaInvasive Cervical Cancer
Lindsay Ferguson, MD24 enrolled1 locationNCT06191133
Recruiting
Phase 1

HPV DNA Vaccine Via Electroporation for HPV16 Positive Cervical Neoplasia

Human Papillomavirus Type 16Cervical Intraepithelial Neoplasia Grade IICervical Intraepithelial Neoplasia, Grade III
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins48 enrolled2 locationsNCT04131413
Recruiting
Phase 1Phase 2

Effect of Honey For CIN II

Cervical Intraepithelial Neoplasia-IIHigh Risk Human Papillomavirus
Zuyderland Medisch Centrum60 enrolled2 locationsNCT06219018
Recruiting
Phase 1

Exploratory Clinical Study of Claudin18.2-Targeted CAR-DC and CAR-T Therapy in Advanced Colorectal Cancer

Colorectal Neoplasia
Second Affiliated Hospital, School of Medicine, Zhejiang University18 enrolled1 locationNCT06946615
Recruiting
Phase 1Phase 2

Avelumab and Methotrexate in in Low-risk Gestational Trophoblastic Neoplasias as First Line Treatment

Gestational Trophoblastic Neoplasias (GTN)
Hospices Civils de Lyon26 enrolled9 locationsNCT04396223
Completed
Phase 1

A single centre, double blind, randomised, parallel group, single and multiple dose, safety and tolerability, pharmacokinetic study of R131-2 vaginal soft gel capsule in healthy women volunteers

Cervical neoplasiaCondyloma acuminatum
Zenith Technology Corporation Limited12 enrolled1 locationACTRN12621001487808
Completed
Phase 1

A single centre, double blind, randomised, parallel group, ascending single and multiple dose, safety and tolerability, pharmacokinetic and pharmacodynamic study of vaginal ointment in healthy women volunteers

Cervical neoplasiaCondyloma acuminatum
Zenith Technology Corp Ltd18 enrolled1 locationACTRN12618000883213