Phase 3 Newly Diagnosed Clinical Trials

11 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 111 of 11 trials

Recruiting
Phase 3

Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia

Newly Diagnosed Philadelphia (Ph)-Negative B-cell Precursor Acute Lymphoblastic Leukemia (ALL)
Amgen304 enrolled192 locationsNCT04994717
Recruiting
Phase 3

A Study of Belantamab Mafodotin Administered in Combination With Lenalidomide and Dexamethasone (BRd) Versus Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Who Are Ineligible for Autologous Stem Cell Transplantation (TI-NDMM)

Multiple MyelomaNewly Diagnosed Multiple Myeloma
GlaxoSmithKline520 enrolled181 locationsNCT06679101
Recruiting
Phase 3

Elranatamab/Lenalidomide Consolidation and/or Elranatamab Maintenance Versus Standard of Care After D-VRd Induction in Transplant-eligible NDMM Patients

Multiple Myeloma, Newly Diagnosed
Intergroupe Francophone du Myelome824 enrolled64 locationsNCT06918002
Recruiting
Phase 2Phase 3

KPD Consolidation After ASCT in NDMM Patients

Multiple Myeloma, Newly Diagnosed
Peking University People's Hospital202 enrolled3 locationsNCT06879379
Recruiting
Phase 3

HVA vs IA/DA or VA in the Treatment of ND HR-AML

Newly Diagnosed Acute Myeloid Leukemia With High Risk
Nanfang Hospital, Southern Medical University876 enrolled1 locationNCT06810791
Recruiting
Phase 2Phase 3

Expression-linked and R-ISS-adapted Stratification for First Line Therapy in Multiple Myeloma Patients

Newly Diagnosed Multiple Myeloma
University Hopsital Schleswig Holstein Campus Lübeck100 enrolled6 locationsNCT05665140
Recruiting
Phase 2Phase 3

Study on the Efficacy and Safety of Low-dose CTX as Maintenance Therapy for MM Unsuitable for Transplantation

Newly Diagnosed Multiple Myeloma
Jinling Hospital, China80 enrolled1 locationNCT06324266
Recruiting
Phase 3

A Randomized Clinical Trial Comparing Chi-BEAM With BEAM Regimen Combined With ASCT for the Treatment of ND PTCL

Newly Diagnosed Peripheral T-cell Lymphoma
The First Affiliated Hospital with Nanjing Medical University104 enrolled1 locationNCT05931263
Completed
Phase 3

A randomized phase III study to compare Bortezomib, Melphalan, Prednisone (VMP) with High Dose Melphalan followed by Bortezomib, Lenalidomide, Dexamethasone (VRD) consolidation and Lenalidomide maintenance in patients with newly diagnosed multiple myeloma

newly diagnosed mutiple myeloma
HOVON1,500 enrolled1 locationACTRN12612000419864
Active
Phase 3

Preventing Invasive Pneumococcal Disease in Children & Adolescents with Leukaemia

Immunogenicity of pneumococcal vaccination in children and adolescents newly diagnosed with Leukaemia, with the aim to protect them from invasive pneumococcal disease
NHMRC CCRE in Childhood and Adolescent Immunisation100 enrolled1 locationACTRN12609000515291
Completed
Phase 3

Efficacy & Safety of Zonisamide in newly diagnosed partial epilepsy patients.

Newly diagnosed partial epilepsy
Eisai Ltd582 enrolled1 locationACTRN12607000142437