Ocular Surface Clinical Trials

12 recruitingLast updated: May 29, 2026

There are 12 actively recruiting ocular surface clinical trials across 9 countries. Studies span Not Applicable, Phase 4. Top locations include Hangzhou, Zhejiang, China, Bologna, Italy, Fountain Valley, California, United States. Updated daily from ClinicalTrials.gov.


Ocular Surface Trials at a Glance

12 actively recruiting trials for ocular surface are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in Hangzhou, Bologna, and Fountain Valley. Lead sponsors running ocular surface studies include Attikon Hospital, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, and AIDS Malignancy Consortium.

Browse ocular surface trials by phase

Treatments under study

About Ocular Surface Clinical Trials

Looking for clinical trials for Ocular Surface? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Ocular Surface trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Ocular Surface clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting

Impact of GLP-1 Receptor Agonists on Dry Eye Disease in Patients With Type 2 Diabetes Mellitus and Obesity

Dry Eye Disease (DED)Diabetes Type 2Diabete Mellitus+3 more
Attikon Hospital100 enrolled1 locationNCT07605572
Recruiting
Not Applicable

The Efficacy of Intradermal Acupuncture for Ocular Surface Diseases After Intractable Facial Paralysis

Ocular Surface DiseaseFacial Paralysis, PeripheralBell's Palsy
The First Affiliated Hospital of Zhejiang Chinese Medical University78 enrolled1 locationNCT07537426
Recruiting
Phase 4

Effect of Acoltremon Ophthalmic Solution 0.003% on Signs and Symptoms of Ocular Surface Disease in Stage I Neurotrophic Keratopathy Patients With Tear Deficiency

Ocular Surface DiseaseNeurotrophic Keratopathy Stage 1
University of South Florida50 enrolled1 locationNCT07502378
Recruiting
Not Applicable

Feasibility Study of Ocular Surface Squamous Neoplasia Surgical Excision in People Living With HIV in Sub-Saharan Africa

HPVOcular Surface Squamous Neoplasia
AIDS Malignancy Consortium84 enrolled1 locationNCT04704648
Recruiting

Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications

GlaucomaOcular Surface Disease
University of California, Los Angeles75 enrolled1 locationNCT04354545
Recruiting
Not Applicable

Eyelid Closure in Keratometry

Dry EyeOcular Surface Disease
Vienna Institute for Research in Ocular Surgery29 enrolled1 locationNCT07297849
Recruiting

Analysis of Videodermatoscopic Parameters of Ocular, Periocular, Conjunctival and Palpebral Neoformations

Ocular Surface Disease
IRCCS Azienda Ospedaliero-Universitaria di Bologna300 enrolled1 locationNCT06714799
Recruiting

Sentinel Lymph Node Biopsy in Ocular Surface and Adnexal Cancers

Ocular Sebaceous CarcinomaOcular Basal Cell CarcinomaOcular Surface Squamous Neoplasia+3 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS25 enrolled1 locationNCT05797415
Recruiting

Clinical Application Research of Scleral Lenses in Ocular Surface Diseases

Ocular Surface Disease
Second Affiliated Hospital, School of Medicine, Zhejiang University20 enrolled1 locationNCT06555367
Recruiting
Not Applicable

Investigator-initiated Clinical Trial to Observe Conjunctival Goblet Cell Using an Anterior Segment Imaging Device

Ocular Surface Disease
Seoul National University Hospital148 enrolled1 locationNCT06427629
Recruiting

The Pattern of Dry Eye Disease After Cataract Surgery

CataractOcular Surface DiseaseDry-Eye Disease
Lithuanian University of Health Sciences100 enrolled1 locationNCT06298890
Recruiting
Phase 4

Effects of preserved and unpreserved low dose topical atropine eye drops on the ocular surface

Dry EyeMyopiaOcular Surface Disease
UNSW Sydney20 enrolled1 locationACTRN12617000571370