Phase 3 Oedema Clinical Trials
10 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–10 of 10 trials
Recruiting
Phase 3
Donidalorsen Treatment in Children With Hereditary Angioedema
Hereditary Angioedema (HAE)
Ionis Pharmaceuticals, Inc.20 enrolled6 locationsNCT07298447
Recruiting
Phase 3
Phase 3 Extension Study of ADX-324 in Participants With Hereditary Angioedema (HAE)
Hereditary Angioedema (HAE)Hereditary Angioedema - Type 1Hereditary Angioedema - Type 2+1 more
ADARx Pharmaceuticals, Inc.90 enrolled48 locationsNCT07428499
Recruiting
Phase 3
STOP-HAE: A Phase 3 Study of ADX-324 in HAE
Hereditary AngioedemaHereditary Angioedema - Type 1Hereditary Angioedema - Type 2+1 more
ADARx Pharmaceuticals, Inc.90 enrolled50 locationsNCT06960213
Recruiting
Phase 3
A Study of Navenibart in Participants With Hereditary Angioedema
Hereditary Angioedema (HAE)
Astria Therapeutics, Inc.145 enrolled85 locationsNCT06842823
Recruiting
Phase 3
Long-Term, Open-label Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE
Hereditary Angioedema (HAE)
Pharvaris Netherlands B.V.170 enrolled24 locationsNCT06679881
Recruiting
Phase 3
Study of Oral Deucrictibant XR Tablet for Prophylaxis and Deucrictibant IR Capsule for On-Demand Treatment of Angioedema Attacks in Adults With Acquired Angioedema Due to C1 Inhibitor Deficiency
Acquired Angioedema Due to C1-Inhibitor Deficiency (AAE-C1-INH)
Pharvaris Netherlands B.V.32 enrolled7 locationsNCT07266805
Recruiting
Phase 3
Anti-vascular Endothelial Growth Factor (Anti-VEGF) Monotherapy vs Anti-VEGF Followed by Subthreshold Micropulse Laser for Treating Severe Diabetic Macular Oedema When the Central Retina Goes <400 Microns
Severe Diabetic Macular Oedema
Belfast Health and Social Care Trust264 enrolled22 locationsNCT06985706
Active
Phase 3
Comparing the effectiveness and safety of two treatments (OZURDEX® intravitreal implant versus Avastin®) for diabetic eye disease in adult Indigenous patients living in Western Australia.
Diabetic Macular Oedema
LIONS EYE INSTITUTE LTD50 enrolled1 locationACTRN12618000202268
Completed
Phase 2Phase 3
Open Label Extension of a Clinical Trial of Intravitreal Triamcinolone for Diabetic Macular Oedema (TDMX study)
Diabetic Macular Oedema
Professor Mark Gillies64 enrolled1 locationACTRN12605000244606
Completed
Phase 2Phase 3
Intravitreal Triamcinolone for Clinically Significant Diabetic Macular Oedema that Persists after Laser Treatment (TDMO)
Diabetic Macular Oedema
Professor Mark Gillies70 enrolled1 locationACTRN12605000211662