Early Phase 1 Open Clinical Trials
12 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–12 of 12 trials
Recruiting
Early Phase 1
Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease
Alzheimer DiseaseMild Cognitive ImpairmentLogopenic Progressive Aphasia+1 more
Massachusetts General Hospital30 enrolled1 locationNCT06538311
Recruiting
Early Phase 1
Early Intervention in High Risk CCUS
Clonal Cytopenia of Undetermined SignificanceCytopenia
Lachelle D. Weeks, MD, PhD108 enrolled1 locationNCT06802146
Recruiting
Early Phase 1
Apixaban in Thrombocytopenia
ThrombocytopeniaDeep Vein ThrombosisPulmonary Embolism and Thrombosis+1 more
Rushad Patell30 enrolled1 locationNCT06886516
Recruiting
Early Phase 1
Single Arm Romiplostim to Prevent CIT
Ewings SarcomaChemotherapy Induced Thrombocytopenia
Children's Hospital Medical Center, Cincinnati26 enrolled2 locationsNCT07048249
Recruiting
Early Phase 1
UCAR-T Targeting CD19/BCMA in Subjects With Autoantibody-Mediated Autoimmune Benign Hematological Diseases
Autoimmune Hemolytic AnemiaEvans SyndromePrimary Immune Thrombocytopenic Purpura
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology27 enrolled1 locationNCT07441525
Recruiting
Early Phase 1
Single Versus Multi-Dose Oral and Intravenous Tranexamic Acid Patients at High Risk for Blood Transfusion After Spine Surgery
Open Posterior Thoracolumbar Spinal Fusion Procedure
Rush University Medical Center604 enrolled1 locationNCT03849443
Recruiting
Early Phase 1
Safety and Efficacy of PRG-1801 in Recurrent/Refractory Primary Immune Thrombocytopenia (ITP)
Immune Thrombocytopenia
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology6 enrolled2 locationsNCT06519565
Recruiting
Early Phase 1
Micro/Nanobubbles (MNBs) for Treatment of Acute and Chronic Wounds
Wound HealOpen Wound
University of California, Irvine40 enrolled1 locationNCT05169814
Recruiting
Early Phase 1
An Exploratory Study of CD19/CD22/BCMA CAR-T Cells (BZE2204) in Subjects With Relapsed or Refractory Autoimmune Diseases
Systemic Lupus Erythematosus (SLE)Immune Thrombocytopenia (ITP)Idiopathic Inflammatory Myopathies(IIM)
Shanghai Cell Therapy Group Co.,Ltd20 enrolled1 locationNCT07174843
Recruiting
Early Phase 1
Safety Study of CC312 in Autoimmune Disease Patients
Rheumatoid Arthritis (RA)Autoimmune Hemolytic AnemiaSystemic Lupus Erythematosus (SLE)+3 more
CytoCares Inc18 enrolled1 locationNCT06888960
Recruiting
Early Phase 1
Serial Blood Count Study
NeutropeniaCongenital NeutropeniaCyclic Neutropenia
University of Washington20 enrolled1 locationNCT07066085
Recruiting
Early Phase 1
An Clinical Study of CD19 CAR NK Cells for the Treatment of Refractory Primary Immune Thrombocytopenia
Thrombocytopenia Alloimmune
Changzhou No.2 People's Hospital9 enrolled1 locationNCT06337474