Open Clinical Trials

625 recruitingLast updated: July 25, 2026

There are 625 actively recruiting open clinical trials across 67 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 1, Phase 4, Early Phase 1. Top locations include Tianjin, Tianjin Municipality, China, Boston, Massachusetts, United States, Beijing, Beijing Municipality, China. Updated daily from ClinicalTrials.gov.


Open Trials at a Glance

625 actively recruiting trials for open are listed on ClinicalTrialsFinder across 6 cities in 67 countries. The largest study group is Not Applicable with 217 trials, with the heaviest enrollment activity in Tianjin, Boston, and Beijing. Lead sponsors running open studies include Institute of Hematology & Blood Diseases Hospital, China, Cairo University, and Peking University People's Hospital.

Treatments under study

About Open Clinical Trials

Looking for clinical trials for Open? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Open trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Open clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 625 trials

Recruiting
Phase 3

A Study of Nipocalimab in Reducing the Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

Thrombocytopenia, Neonatal Alloimmune
Janssen Research & Development, LLC39 enrolled21 locationsNCT06449651
Recruiting

Multimodal Nutritional and Sarcopenia Assessment for Risk Stratification in Lung Cancer Surgery

SarcopeniaLung Cancer (Non-Small Cell)Malnutrition Severe
Ondokuz Mayıs University142 enrolled1 locationNCT07500376
Recruiting
Phase 1

Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)

Antiphospholipid Syndrome (APS)Immune-mediated Necrotizing Myopathy (IMNM)Immune Thrombocytopenia (ITP)+3 more
Chugai Pharmaceutical144 enrolled77 locationsNCT06371417
Recruiting
Not Applicable

The Effectiveness of Squat Exercise for Improving Pre-Sarcopenia in Order Adults

Sarcopenia
Tzu Chi University80 enrolled1 locationNCT07726758
Recruiting

Comparison of Preoperative Frailty Assessment Tools

FrailtyFrailty/SarcopeniaFrailty in Older Adults
Universitätsklinikum Hamburg-Eppendorf584 enrolled1 locationNCT06889545
Recruiting
Phase 2

Statins in Patients With Clonal Cytopenia of Undetermined Significance (CCUS) and Myelodysplastic Syndromes (MDS)

Myelodysplastic SyndromesClonal Cytopenia of Undetermined Significance
Washington University School of Medicine16 enrolled1 locationNCT05483010
Recruiting
Phase 2

Phase II Study of QLC2519 in Pediatric Solid Tumor Participants

NeutropeniaFebrile Neutropenia (FN)Pediatric Malignant Solid Tumor
Qilu Pharmaceutical Co., Ltd.18 enrolled1 locationNCT07724756
Recruiting
Not Applicable

The Effectiveness and Safety of Combined Research on Uremic Sarcopenia

Sarcopenia
Ningbo Medical Center Lihuili Hospital76 enrolled1 locationNCT07724587
Recruiting
Not Applicable

Effects of Resistance Training on Sarcopenia in Older Patients With Chronic Heart Failure

Chronic Heart FailureSarcopenia in Elderly
Kieu Dang Phuong Nguyen146 enrolled2 locationsNCT06785168
Recruiting
Phase 3

A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

Primary Open Angle Glaucoma
AbbVie130 enrolled27 locationsNCT06822738
Recruiting

Sarcopenia Indicators After Bariatric Surgery

SarcopeniaObesityBariatric Surgery
Hatice Zehra FERHATLAR80 enrolled1 locationNCT07717333
Recruiting
Not Applicable

Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal Study

Alzheimer DiseaseAlzheimer Disease, Early OnsetLogopenic Progressive Aphasia (LPA)+5 more
Mayo Clinic60 enrolled1 locationNCT02740634
Recruiting

Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ Lymphocytopenia

Cryptococcal MeningitisWartsIdiopathic CD4+ Lymphocytopenia
National Institute of Allergy and Infectious Diseases (NIAID)950 enrolled1 locationNCT00867269
Recruiting
Phase 2

Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models

Idiopathic CD4-PositiveT-Lymphocytopenia
National Institute of Allergy and Infectious Diseases (NIAID)40 enrolled1 locationNCT02015013
Recruiting
Not Applicable

Exploration on the Relationship Between Distinct Sarcopenia, Traditional Chinese Medicine Body Constitution, and Circadian Rhythm Patterns of Older Adults and Impact of Acupoint-stimulated Interventions

SarcopeniaSleep Wake Disorders
Tainan Hospital, Ministry of Health and Welfare360 enrolled1 locationNCT07715721
Recruiting
Phase 2

Study of Ianalumab in Adults With Primary Immune Thrombocytopenia (ITP) and Warm-antibody Autoimmune Hemolytic Anemia (wAIHA) Who Have Previously Benefited From Ianalumab

Warm Autoimmune Hemolytic AnemiaPrimary immune thrombocytopenia
Novartis Pharmaceuticals60 enrolled25 locationsNCT07039422
Recruiting

PRESERFLO™ MicroShunt XI Observational PMCF Study With no Control Group

Primary Open Angle Glaucoma
Santen SAS112 enrolled11 locationsNCT07235592
Recruiting
Phase 1Phase 2

Safety and Preliminary Efficacy of CTX112 in Adult Participants With Relapsed/Refractory Hematologic Autoimmune Disease

Immune Thrombocytopenic PurpuraITP - Immune ThrombocytopeniaWarm Autoimmune Hemolytic Anemia+1 more
CRISPR Therapeutics AG60 enrolled8 locationsNCT07549698
Recruiting
Not Applicable

Antibiotic Duration and Outcomes in High-Risk Febrile Neutropenia Patients

bloodstream infectionGram-negative InfectionsBacteraemia Caused by Gram-Negative Bacteria+1 more
Valeria Cento172 enrolled1 locationNCT07372131
Recruiting
Phase 1

OM336 in Autoimmune Cytopenias

ITP - Immune ThrombocytopeniaAIHA - Warm Autoimmune Hemolytic AnemiaAIHA - Cold Autoimmune Hemolytic Anemia
Lakefront Biotherapeutics West LLC32 enrolled3 locationsNCT07083960