Open Clinical Trials

580 recruitingLast updated: May 21, 2026

There are 580 actively recruiting open clinical trials across 66 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 1, Phase 4, Early Phase 1. Top locations include Tianjin, Tianjin Municipality, China, Beijing, Beijing Municipality, China, Boston, Massachusetts, United States. Updated daily from ClinicalTrials.gov.


Open Trials at a Glance

580 actively recruiting trials for open are listed on ClinicalTrialsFinder across 6 cities in 66 countries. The largest study group is Not Applicable with 203 trials, with the heaviest enrollment activity in Tianjin, Beijing, and Boston. Lead sponsors running open studies include Institute of Hematology & Blood Diseases Hospital, China, Peking University People's Hospital, and Assistance Publique - Hôpitaux de Paris.

About Open Clinical Trials

Looking for clinical trials for Open? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Open trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Open clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 580 trials

Recruiting

Serologic Response to Pneumococcal Vaccination Among Esophageal Cancer Patients With High Grade Lymphopenia After Chemoradiation

Esophageal CancerChemoradiationPneumococcal Vaccine+1 more
M.D. Anderson Cancer Center80 enrolled1 locationNCT06181656
Recruiting
Not Applicable

Preoperative Prehabilitation for Sarcopenic Patients Prior to Pancreatic Surgery for Cancer

SarcopeniaPancreatic Cancer
University Hospital, Lille158 enrolled1 locationNCT04469504
Recruiting
Not Applicable

MyokinE100 System: Closed Loop Electrical Muscle Stimulation to Mitigate ICU Acquired Weakness in Medical ICU Patients

ICU acquired weaknessSarcopeniaSepsis+4 more
Health Discovery Labs50 enrolled3 locationsNCT07362862
Recruiting
Phase 1

Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)

Open-angle Glaucoma (OAG)NAION( Non-arteritic Anterior Ischemic Optic Neuropathy)
Life Biosciences Inc.18 enrolled4 locationsNCT07290244
Recruiting
Not Applicable

Evaluation of Safety and Efficacy of a Digital Therapeutic Device to Improve Strength in Sarcopenia (Sarc-DTx)

Sarcopenia
Exosystems130 enrolled2 locationsNCT07319377
Recruiting
Not Applicable

Additive Efficacy of Physical Activity Program in Hypthyroidism Elder Females With Glaucoma and Fatty Liver Issues

Non-Alcoholic Fatty Liver DiseaseSubclinical hypothyroïdismPrimary Open Angle Glaucoma
Cairo University40 enrolled1 locationNCT07599241
Recruiting
Not Applicable

IOA Preventing Occlusal Changes With MAD Use

SnoringObstructive Sleep Apnea (OSA)Sleep Related Breathing Disorder+4 more
Isabel Moreno Hay30 enrolled1 locationNCT07103941
Recruiting

Effect of Sarcopenia and Frailty on Rocuronium Pharmacodynamics in Geriatric Patients

SarcopeniaFrailtyNeuromuscular Blockade+2 more
Konya Meram State Hospital100 enrolled1 locationNCT07580144
Recruiting
Phase 1Phase 2

JAK1/2 Inhibitor Ruxolitinib for Relapsed/Refractory Immune Bone Marrow Failure

Severe Aplastic AnemiaSingle Lineage Cytopenias, T-LGLHypoplastic MDS
National Heart, Lung, and Blood Institute (NHLBI)145 enrolled1 locationNCT05998408
Recruiting
Phase 2

TCM Formula vs. HMB in Pre-Frail Elders: Muscle Strength and Bone Status

pre frailtySarcopeniaOsteoporosis+2 more
Tri-Service General Hospital90 enrolled1 locationNCT07597850
Recruiting
Phase 2

Safety and Efficacy Study of PF-06835375 in Primary Immune Thrombocytopenia

Primary immune thrombocytopenia
Pfizer91 enrolled31 locationsNCT05070845
Recruiting

CHAPTER: Clonal Haematopoiesis Assessment: Prevention, Treatment and Research

Clonal HematopoiesisHematologic Disease and DisordersCCUS Clonal Cytopenia of Undetermined Significance
Clinical Hub for Interventional Research (CHOIR)100 enrolled1 locationNCT07313059
Recruiting
Not Applicable

Blood Flow Restriction Training in Acute Geriatric Rehabilitation

Sarcopenia in Elderly
University Hospital, Bonn60 enrolled1 locationNCT07291765
Recruiting
Phase 1Phase 2

A Study of Pirtobrutinib in Participants With Immune Thrombocytopenia

Immune Thrombocytopenia (ITP)
Eli Lilly and Company58 enrolled45 locationsNCT06721013
Recruiting
Phase 3

A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

Primary Open Angle Glaucoma
AbbVie130 enrolled22 locationsNCT06822738
Recruiting
Phase 2

A Study of PLH-2301 in Subjects With Sarcopenia

Sarcopenia in Elderly
Pluto Inc.168 enrolled5 locationsNCT07390552
Recruiting
Phase 2

Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models

Idiopathic CD4-PositiveT-Lymphocytopenia
National Institute of Allergy and Infectious Diseases (NIAID)40 enrolled1 locationNCT02015013
Recruiting
Phase 2

Romiplostim N01 Plus ATRA for Persistent Isolated Chemotherapy-Induced Thrombocytopenia After Complete Remission of Gastrointestinal Solid Tumors

Colorectal, CancerPancreatic CancerGastrointestinal Neoplasms+2 more
Peking University People's Hospital220 enrolled1 locationNCT07586813
Recruiting
Phase 2

Romiplostim N01 Plus ATRA for Persistent Isolated Chemotherapy-Induced Thrombocytopenia After Complete Remission of Gynecologic, Breast, or Lung Solid Tumors

Breast CancerGynecologic CancersOvarian Cancer+7 more
Peking University People's Hospital220 enrolled1 locationNCT07586826
Recruiting
Not Applicable

Investigate the Effectiveness of 3D-printed Shape Memory Aligners in the Treatment of Anterior Open Bite

Open Bite
Kufa University51 enrolled1 locationNCT07420777