Phase 4 Oral Clinical Trials

19 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 119 of 19 trials

Recruiting
Phase 4

An Extension Test of Whether to Use Oral Anti-anxiety Drugs (Alprazolam) When Patients Choose Second Eye Cataract Surgery After Unblinding, and Analyze Their Anxiety, Satisfaction and Pain Satisfaction

OphthalmologyCataract Surgery AnesthesiaOral Anxiolytic+1 more
National Taiwan University Hospital250 enrolled1 locationNCT06874452
Recruiting
Phase 4

Using a Steroid Mouthwash to Prevent Mouth Sores During Chemotherapy

Oral Mucositis Due to Chemotherapy
Woman's45 enrolled1 locationNCT07287826
Recruiting
Phase 4

Bupivacaine Liposome Plus Bupivacaine or Ropivacaine for Pericapsular Nerve Group Block in Hip Arthroplasty (PENG)

Hip FracturesFemoral Neck FracturesFemur Head Necrosis
Huazhong University of Science and Technology60 enrolled1 locationNCT06565910
Recruiting
Phase 4

This is a Study to Verify if Periarticular Hip Injection of Corticosteroid After Hip Replacement Reduce the Pain and the Hospitalisation Time

Femoral Neck Fractures
Ente Ospedaliero Cantonale, Bellinzona110 enrolled1 locationNCT05023369
Recruiting
Phase 4

Treatment of Perioral Wrinkles Using Topical Poly-L-lactic Acid and Microneedling Device

Perioral Wrinkles
Skincare Physicians of Chestnut Hill26 enrolled1 locationNCT07225348
Recruiting
Phase 4

Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients

ConfusionCognitive DysfunctionMolecular Mechanisms of Pharmacological Action+14 more
Sunnybrook Health Sciences Centre2,400 enrolled8 locationsNCT04289142
Recruiting
Phase 4

Evaluation of Efficacy and Safety of add-on Tofacitinib in Patients With Oral Lichen Planus

Oral Lichen Planus
All India Institute of Medical Sciences, Bhubaneswar60 enrolled1 locationNCT07131813
Recruiting
Phase 4

Effects of Energy Drinks on Cardiovascular Endpoints

Healthy VolunteersSafety After Oral Intake
University of the Pacific3 enrolled1 locationNCT07212803
Recruiting
Phase 4

The Use of CCK vs PS in Revision TKAs

Aseptic Loosening of Prosthetic JointInstability of Prosthetic JointReimplantation for Periprosthetic Joint Infection+2 more
Rush University Medical Center170 enrolled1 locationNCT06782295
Recruiting
Phase 4

Serial Magnetic Resonance Imaging for the Prediction of Radiation-Induced Changes in Normal Tissue of Patients With Oral Cavity or Skull Base Tumors

OsteoradionecrosisMalignant Oral Cavity NeoplasmMalignant Skull Base Neoplasm
M.D. Anderson Cancer Center425 enrolled1 locationNCT04265430
Recruiting
Phase 4

Immunogenicity of Gardasil-9 HPV Vaccine in People Living With HIV

Papillomavirus InfectionHuman Immunodeficiency VirusCervical Intraepithelial Neoplasia+4 more
Louisiana State University Health Sciences Center in New Orleans250 enrolled1 locationNCT05266898
Recruiting
Phase 4

Lemborexant for Insomnia in a Patient With Dementia: An N-of-1 Trial

InsomniaDementiaFrontotemporal Dementia
Nova Scotia Health Authority1 enrolled1 locationNCT06093126
Recruiting
Phase 4

Contraceptive Hormone and Reward Measurement (CHARM Study)

MoodNeural ActivityOral Hormonal Contraceptive Use+1 more
University of Colorado, Denver144 enrolled1 locationNCT05058872
Recruiting
Phase 4

Monotherapy With P2Y12 Inhibitors in Patients With Atrial fIbrillation Undergoing Supraflex Stent Implantation

Atrial Fibrillation (AF)Percutaneous Coronary Intervention (PCI)Oral Anticoagulation+1 more
Insel Gruppe AG, University Hospital Bern3,010 enrolled15 locationsNCT05955365
Recruiting
Phase 4

Comparison of Remimazolam and Propofol for Recovery of Ambulatory Upper Airway Surgery

Laryngeal DiseaseNasal DiseaseOral Cavity Disease+1 more
Chung-Ang University Gwangmyeong Hospital116 enrolled1 locationNCT06507202
Recruiting
Phase 4

The Effect of Systemic Antibiotics on Post-surgical Complications and Patient-centered Outcomes in Patients Undergoing Implant Surgery With Guided Bone Regeneration and Simultaneous Sinus Floor Elevation

Patients Undergoing Oral Implant Therapy
Medical University of Graz30 enrolled1 locationNCT04552080
Completed
Phase 4

A pilot study to compare discontinuation, side-effects, cost-effectiveness and implementation challenges between 3rd and 2nd generation Oral Contraceptive Pill (OCP) in one upazilla in Bangladesh

Oral contraception
Ministry of Health and Family Welfare1,400 enrolled1 locationACTRN12622001062718
Completed
Phase 4

A double blind randomised controlled trial assessing the effect of 30% topical lidocaine gel on reducing pain in patients presenting to a cosmetic surgery practice with either prominent periorbital or lateral temporal veins for treatment with Neodymium-Doped Yttrium Aluminum Garnet (ND:TAG))

Periorbital and lateral temporal veins - cosmetic
University of Toronto10 enrolled1 locationACTRN12613000996763
Completed
Phase 4

The Glucose Tolerance Test Study

Anti-inflammatory effect of insulin after Oral versus intravenous glucose in overweight individuals.
Universtiy of otago15 enrolled1 locationACTRN12612000491864