Phase 2 Oropharynx Cancer Clinical Trials
13 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–13 of 13 trials
Recruiting
Phase 2
Methotrexate, Erlotinib, and Celecoxib for the Treatment of Recurrent/Metastatic Head and Neck Cancer in a Rural Midwest United States Population
Head and Neck CancerOropharynx CancerHypopharynx Cancer+3 more
Mayo Clinic25 enrolled1 locationNCT06997068
Recruiting
Phase 2
A Study on Using Cell-Free Tumor DNA (ctDNA) Testing to Decide When to StartRoutine Treatment in People With Human Papilloma Virus (HPV)- Associated Oropharynx Cancer (OPC)
HPV-Related MalignancyHPV-Related CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma+2 more
Memorial Sloan Kettering Cancer Center30 enrolled8 locationsNCT05307939
Recruiting
Phase 1Phase 2
E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers
Cervical CancerAnal CancerPenile Cancer+14 more
Christian Hinrichs15 enrolled2 locationsNCT05639972
Recruiting
Phase 2
E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers
Cervical CancerMetastatic CancerAnal Cancer+18 more
Christian Hinrichs20 enrolled3 locationsNCT05686226
Recruiting
Phase 2
A Study of Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Cancer (HNSCC)
Squamous Cell Carcinoma of Head and NeckOral Cavity CancerNasal Cavity Cancer+9 more
Memorial Sloan Kettering Cancer Center40 enrolled7 locationsNCT07063212
Recruiting
Phase 2
Personalized Volume-deescalated Elective Nodal Irradiation in Oropharyngeal Head and Neck Squamous Cell Carcinoma
Oropharynx Cancer
University of Zurich120 enrolled5 locationsNCT06563362
Recruiting
Phase 2
Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL)
Head and Neck CancerHead and Neck Squamous Cell CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma+2 more
University of Maryland, Baltimore61 enrolled5 locationsNCT06088381
Recruiting
Phase 2
Neoadjuvant Immunoradiotherapy With Evorpacept and Pembrolizumab in HPVOPC (Human Papilloma Virus Oropharynx Cancer)
Oropharynx Cancer
University of California, San Diego29 enrolled3 locationsNCT05787639
Recruiting
Phase 2
Transoral Surgical Resection Followed by De-escalated Adjuvant IMRT in Resectable p16+ Locally Advanced Oropharynx Cancer
Oropharynx Cancer
Heath Skinner150 enrolled1 locationNCT05388773
Recruiting
Phase 2
Lymphoscintigraphy Directed Elective Neck Radiation for p16+ Favorable Risk Oropharynx Cancer
Oropharynx Cancer
Fox Chase Cancer Center22 enrolled1 locationNCT05800574
Recruiting
Phase 2
Testing Less Intensive Radiation With Chemotherapy to Treat Low-risk Patients With HPV-positive Oropharyngeal Cancer
HPV Positive Oropharyngeal Squamous Cell CarcinomaOropharynx CancerThroat Carcinoma+1 more
University of Missouri-Columbia28 enrolled1 locationNCT04444869
Recruiting
Phase 2
Adaptive RadioTherapy for OroPharynx Cancer
Radiotherapy Side EffectMRIRadiotherapy; Complications+2 more
Centre hospitalier de l'Université de Montréal (CHUM)120 enrolled2 locationsNCT04901234
Recruiting
Phase 2
Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharyngeal Cancer.
Throat CancerOropharynx CancerTonsil Cancer+1 more
Nader Sadeghi60 enrolled1 locationNCT04277858