Orthopedic Surgery Clinical Trials

8 recruitingLast updated: July 25, 2026

There are 8 actively recruiting orthopedic surgery clinical trials across 5 countries. Studies span Not Applicable, Phase 3. Top locations include Cairo, Egypt, Amsterdam, North Holland, Netherlands, Antalya, Turkey (Türkiye). Updated daily from ClinicalTrials.gov.


Orthopedic Surgery Trials at a Glance

8 actively recruiting trials for orthopedic surgery are listed on ClinicalTrialsFinder across 5 cities in 5 countries. The largest study group is Not Applicable with 3 trials, with the heaviest enrollment activity in Cairo, Amsterdam, and Antalya. Lead sponsors running orthopedic surgery studies include Cairo University, Antalya Health Sciences University, and Ain Shams University.

Browse orthopedic surgery trials by phase

Treatments under study

About Orthopedic Surgery Clinical Trials

Looking for clinical trials for Orthopedic Surgery? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Orthopedic Surgery trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Orthopedic Surgery clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 18 of 8 trials

Recruiting

Preoperative Anxiety and One-year Patient-reported Outcomes in Orthopedic Surgery Patients Receiving Enhanced Recovery After Surgery or Conventional Care

Preoperative AnxietyPatient Reported Outcome (PRO)Orthopedic Surgery
Buddhist Tzu Chi General Hospital220 enrolled1 locationNCT07706244
Recruiting

Comparison of Debridement, Antibiotic, Implant Retention and Implant Exchange in Early-stage Fracture-related Infections

Orthopedic SurgeryFracture Related InfectionDebridement+2 more
Antalya Health Sciences University75 enrolled1 locationNCT07669714
Recruiting
Not Applicable

Intrathecal Dexmedetomidine With Bupivacaine, in Patients Undergoing Knee Orthopedic Surgery

BupivacaineIntrathecal DexmedetomidineKnee Orthopedic Surgery
Cairo University120 enrolled1 locationNCT07522736
Recruiting

Femoral Vein Diameter to Predict Intraoperative Hypotension in Geriatric Patients Undergoing Orthopedic Surgery Under Spinal Anesthesia

Intraoperative hypotensionSpinal AnesthesiaOrthopedic Surgery+1 more
Cairo University43 enrolled1 locationNCT07339475
Recruiting
Not Applicable

Ketamine for Preventing Post-Spinal Hypotension in Orthopedic Surgery

Orthopedic SurgeryPost-spinal HypotensionSpinal Aneshtesia
Ain Shams University30 enrolled1 locationNCT06995690
Recruiting
Phase 3

Intraoperative Methadone for the Prevention of Postoperative Pain

Orthopedic Surgery
Brugmann University Hospital80 enrolled1 locationNCT05831345
Recruiting
Not Applicable

Intermittent Fasting Versus Carbohydrate Drinks Before Surgery

Insulin ResistancePerioperative CareIntermittent Fasting+3 more
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)75 enrolled1 locationNCT05760339
Recruiting

The effect of adding magnesium sulphate to fentanyl and bupivacaine for spinal anaesthesia in patients undergoing lower limb orthopedic surgery

duration of spinal anaesthesia in lower limb orthopedic surgery
mansura university hospital99 enrolled1 locationACTRN12615000508572