Phase 1 Osteoarthritis of the knee Clinical Trials
5 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–5 of 5 trials
Recruiting
Phase 1
Study to Assess the Safety and Pharmacokinetics of AVD275 Injection in Patients With Osteoarthritis of the Knee
Osteoarthritis of the knee
Avidence Therapeutics15 enrolled1 locationNCT07338266
Recruiting
Phase 1
Bioequivalence Assessment of Topical Smartech 2% Diclofenac Sodium Solution Compared to a Reference Product When Applied to the Knees of Healthy Male and Female Participants
Osteoarthritis of the knee
Smartech Topical AU Pty Ltd90 enrolled1 locationACTRN12624000341527
Completed
Phase 1
A Phase I, Open-Label Study to Evaluate the Safety and Pharmacokinetics of APC201 in Healthy Volunteers
AnaesthesiologyPain associated with osteoarthritis of the knee
Andros Pharmaceuticals Pty Ltd10 enrolled1 locationACTRN12623000261617
Recruiting
Phase 1
A Randomized, Controlled, Double-Blind Study of a Single Intra-Articular Injection of the less than 5,000 MW Fraction of Human Albumin 5% (Ampion-Trademark) in Adults with Osteoarthritis of the Knee
Osteoarthritis of the knee
Ampio Pharmaceuticals60 enrolled1 locationACTRN12611000940976
Recruiting
Phase 1
A randomised trial comparing the effect of green-lipped mussel and glucosamine in treating osteoarthritis of the knee and assessing if this correlates to the nutraceuticals improving gut integrity
Irritable Bowel SymptomsOsteoarthritis of the knee
The University of Queensland40 enrolled1 locationACTRN12611000658910