Otitis Media Clinical Trials

7 recruiting

Frequently Asked Questions

Common questions about Otitis Media clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 116 of 16 trials

Recruiting
Not Applicable

Evaluation of the Medentum Diagnostik Platform for Pediatric ENT Conditions and Asthma

Pediatric AsthmaAsthma ExacerbationAcute Otitis Media (AOM)+1 more
Medentum Innovations84 enrolled1 locationNCT07500532
Recruiting
Phase 2

Safety and Efficacy of wSp Vaccine in Young Children

Acute Otitis Media (AOM)
Serum Life Science Europe GmbH320 enrolled4 locationsNCT07216430
Recruiting
Not Applicable

Coherent Optical Detection of Middle Ear Disease

Otitis Media
Medical College of Wisconsin235 enrolled2 locationsNCT05353569
Recruiting
Not Applicable

Impact of a Multimodal Intervention on Antibiotic Prescribing for Respiratory Infections in Primary Care

AnginaAcute BronchiolitisAcute Bronchitis+8 more
University Hospital, Caen4,500 enrolled1 locationNCT07359287
Recruiting
Not Applicable

Artificial Intelligence Diagnostic Decision Support to Reduce Antimicrobial Prescriptions in Young Children With Colds

Acute Otitis Media (AOM)Upper Respiratory Infection
Timothy Shope300 enrolled2 locationsNCT06876259
Recruiting
Not Applicable

Interventions to De-implement Unnecessary Antibiotic Prescribing for Children With Ear Infections

Ear InfectionPediatric Infectious DiseaseAcute Otitis Media
Intermountain Health Care, Inc.1,566 enrolled3 locationsNCT06034080
Recruiting
Not Applicable

Respiratory Tract Microbiome and Probiotics in Children With Cleft Palate

Cleft Palate ChildrenOtitis Media in Children
University Hospital, Antwerp40 enrolled1 locationNCT06505330
Recruiting
Phase 4

Does Topical Otic Drop Use at Time of Tympanostomy Tube Surgery Improve Outcomes When no Middle Ear Effusion is Present

Otitis Media
Boston Children's Hospital125 enrolled1 locationNCT03655665
Recruiting

Perth Children's Hospital (PCH) Healthy Ears: A telehealth-facilitated randomised-controlled trial utilising a health promotion intervention to resolve otitis media with effusion for children on specialist Ear, Nose and Throat (ENT) waiting lists.

Otitis Media with Effusion
Telethon Kids Institute250 enrolled1 locationACTRN12622000546752
Recruiting

Deadly Ears in Deadly Hands: Aboriginal Health Professional-led ear and hearing assessment and discharge planning for Aboriginal children at risk of severe ear infection

severe otitis media
Menzies School of Health Research600 enrolled1 locationACTRN12622000478718
Recruiting

A non-invasive treatment for Otitis Media with Effusion

otitis media with effusion (OME)
Curtin University25 enrolled1 locationACTRN12621000949886
Recruiting
Phase 2

ATOMIC Ears: A Phase IIB randomised controlled trial to assess safety, tolerability and acceptability of a 5-day Dornase alfa treatment as an adjunct therapy to ventilation tube insertion for otitis media in children

Recurrent acute otitis mediaChronic otitis media with effusion ("glue ear")
Telethon Kids Insitute120 enrolled5 locationsACTRN12619001306101
Recruiting

Cockburn Ear Portal: An Ears, Nose and Throat (ENT) and Audiology referral portal for improving access to ear health services for Aboriginal children in metropolitan areas using telehealth

Otitis Media
Telethon Kids Institute120 enrolled1 locationACTRN12619000040167
Recruiting

PCH Ear Portal: An urban-based Ears, Nose and Throat (ENT) and Audiology referral telehealth portal to provide equitable access to specialist ear health services for children

Otitis Media
Telethon Kids Institute360 enrolled1 locationACTRN12619000039189
Recruiting
Phase 3Phase 4

A randomised controlled trial of pneumococcal conjugate vaccines Synflorix and Prevenar13 in sequence or alone in high-risk Indigenous infants (PREV-IX): immunogenicity, carriage and otitis media outcomes

Non-typeable Haemophilus influenzae diseaseOtitis media in Indigenous infantsPneumococcal disease
Menzies School of Health Research425 enrolled1 locationACTRN12610000544077
Recruiting
Phase 3Phase 4

Antibtiotics for Asymptomatic Acute Otitis Media

Acute otitis media without perforation
Menzies School of Health Research300 enrolled1 locationACTRN12608000424303