Phase 2 Parkinson Clinical Trials

62 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 62 trials

Recruiting
Phase 2Phase 3

A Study of Buntanetap in Participants With PD

Deep Brain StimulationParkinson's Disease (PD)
Annovis Bio Inc.500 enrolled27 locationsNCT07284784
Recruiting
Phase 1Phase 2

The University of Alabama at Birmingham (UAB) Neuroinflammation in Parkinson's Disease-TSPO- Positron Emission Tomography (PET) Substudy

Parkinson Disease
University of Alabama at Birmingham205 enrolled1 locationNCT03457493
Recruiting
Phase 2

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

Parkinson DiseaseParkinsonParkinson Disease, Idiopathic+2 more
Neuron23 Inc.150 enrolled70 locationsNCT06680830
Recruiting
Phase 1Phase 2

rTMS to Improve Cognition in Parkinson's

Mild Cognitive ImpairmentParkinson's Disease
VA Office of Research and Development56 enrolled2 locationsNCT03836950
Recruiting
Phase 2

Ketamine for Veterans With Parkinson's Disease

Parkinson's Disease
VA Office of Research and Development80 enrolled1 locationNCT06231563
Recruiting
Phase 2

A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

Parkinson Disease
Appello Pharmaceuticals, Inc.150 enrolled25 locationsNCT07432958
Recruiting
Phase 2

Etoricoxib in Patients With Parkinsonian Disease

Parkinson Disease
Ihab Elsayed Hassan60 enrolled1 locationNCT07370532
Recruiting
Phase 2

Intranasal Insulin and Glutathione as an Add-On Therapy in Parkinson's Disease

Parkinson Disease
Gateway Institute for Brain Research56 enrolled2 locationsNCT05266417
Recruiting
Phase 2

A Phase 2 Study to Assess the Effects of SUL-238 on High Energy Phosphates With ³¹P-MRS in Patients With Early, Untreated Parkinson's Disease

Parkinson's Disease (PD)
GEN İlaç ve Sağlık Ürünleri A.Ş.45 enrolled1 locationNCT07322887
Recruiting
Phase 2

18F-mFBG Cardiac Uptake With Lewy Body Dementia

Lewy Body Dementia (LBD)Parkinson Disease (PD)
Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC)20 enrolled1 locationNCT07176286
Recruiting
Phase 2

Reducing Falls With Varenicline in Hypocholinergic Parkinson Disease

Parkinson Disease
Vikas Kotagal102 enrolled1 locationNCT06679374
Recruiting
Phase 2

Probiotic Treatment for Depression and Associated Mood Disorders in Parkinson's Disease

DepressionParkinson DiseasePARKINSON DISEASE (Disorder)
University of British Columbia60 enrolled1 locationNCT05568498
Recruiting
Phase 2

Safety, Tolerability and Symptomatic Efficacy of the ROCK-Inhibitor Fasudil in Patients With Parkinson's Disease

Idiopathic Parkinson´s Disease
Technical University of Munich75 enrolled1 locationNCT05931575
Recruiting
Phase 2Phase 3

Montelukast in Parkinson Disease

Parkinson Disease
Mostafa Bahaa60 enrolled1 locationNCT06113640
Recruiting
Phase 2

Imaging Depression in Parkinson's Disease

Major Depressive DisorderParkinson's Disease
Yale University120 enrolled1 locationNCT06402955
Recruiting
Phase 1Phase 2

Safety and Tolerability of IRL757 in Participants With Parkinson's Disease and Apathy

SafetyPARKINSON DISEASE (Disorder)Apathy
Integrative Research Laboratories AB75 enrolled13 locationsNCT07461220
Recruiting
Phase 1Phase 2

A Multicenter Study to Evaluate Safety, Tolerability, and Clinical Responses of DSP-1083 Into Subjects With Parkinson's Disease

Parkinson's Disease
Sumitomo Pharma America, Inc.25 enrolled2 locationsNCT06753331
Recruiting
Phase 2

A Trial to Test the Use of Dapansutrile, an Anti-inflammatory Medication, in People With Parkinson's Disease

Parkinson Disease
Cambridge University Hospitals NHS Foundation Trust36 enrolled1 locationNCT07157735
Recruiting
Phase 2

IMPACT 360 for Parkinson's Disease

Parkinson's Disease (PD)REM Sleep Behavior Disorder
University of British Columbia60 enrolled1 locationNCT07443293
Recruiting
Phase 2

Pyridostigmine for the Treatment of Constipation in Parkinson Disease

ConstipationParkinson Disease
University of Vermont Medical Center16 enrolled1 locationNCT05603715