Phase 1 Patient Clinical Trials
79 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 79 trials
Recruiting
Phase 1Phase 2
Immunological Reset to Enable Access to Hla-compatible Kidney Transplantation in Highly Sensitized Patients (RESET)
Kidney TransplantationKidney Failure, ChronicAlloimmunization+3 more
Hospital Universitari Vall d'Hebron Research Institute10 enrolled1 locationNCT07607197
Recruiting
Phase 1Phase 2
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
Type 1 DiabetesType 1 Diabetes MellitusType 1 Diabetes Mellitis+7 more
COUR Pharmaceutical Development Company, Inc.72 enrolled30 locationsNCT06783309
Recruiting
Phase 1
Semaglutide (SEMA) for Alcohol Use Disorder (AUD) After Metabolic and Bariatric Surgery (MBS)
Weight LossAlcohol Use DisorderBariatric Surgery Patients
Yale University10 enrolled1 locationNCT07223983
Recruiting
Phase 1
TSL2109 Capsules in Advanced Solid Tumor Patients: Safety, Tolerability, PK and Preliminary Efficacy
Metastatic Castration-Resistant Prostate Cancer Patients
Tasly Pharmaceutical Group Co., Ltd78 enrolled1 locationNCT07514065
Recruiting
Phase 1
A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)
Metastatic Castration-resistant Prostate Cancer (mCRPC)Metastatic Castration-resistant Prostate CancermCRPC (Metastatic Castration-resistant Prostate Cancer)+2 more
K36 Therapeutics, Inc.144 enrolled13 locationsNCT07103018
Recruiting
Phase 1
Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients
ObesitySmoking CessationBariatric Surgery Patients
Yale University20 enrolled1 locationNCT07224087
Recruiting
Phase 1
Trial of pTVG-HP+Nivo+Targeted Ablation of Resistant Lesions in Non-Castrate RecurrentOMPC
Prostate Cancer PatientsRecurrent Prostate CancerOligometastatic Prostate Cancer (OMPC)+1 more
University of Wisconsin, Madison14 enrolled1 locationNCT07090148
Recruiting
Phase 1Phase 2
SNB-101 for Treatment of Extensive Stage Small Cell Lung Cancer
Patient is Not Suitable for Complete Surgical Resection With a Cytologically or Histologically Confirmed Small Cell Lung Cancer(SCLC)
SN BioScience55 enrolled1 locationNCT07391813
Recruiting
Phase 1
A Study Testing Topical Pain-Relieving Herbal Plasters in People Who Are Using Opioids for Their Pain
Cancer PainCancer PatientsSurvivor Patients
Memorial Sloan Kettering Cancer Center150 enrolled7 locationsNCT07447856
Recruiting
Phase 1Phase 2
Linaclotide for Colonoscopy Bowel Prep
Patients Scheduled for Colonoscopy
University of Florida10 enrolled1 locationNCT06692673
Recruiting
Phase 1Phase 2
Phase I/II Clinical Study of SHR-1501 Combined With Adbelizumab in Patients With Malignant Tumors
Patients With Advanced or Metastatic Malignant Tumors
Shanghai Hengrui Pharmaceutical Co., Ltd.203 enrolled1 locationNCT07073534
Recruiting
Phase 1
A Pharmacokinetic Study of TS-172 in Patients With Hepatic Impairment
Patients With Mild or Moderate Hepatic Impairment
Taisho Pharmaceutical Co., Ltd.24 enrolled1 locationNCT07231029
Recruiting
Phase 1
Study of NXP900 With Osimertinib in Subjects With Advanced, EGFR-Mutated Non-Small Cell Lung Cancer
EGFR Mutation Positive Non-small Cell Lung CancerEGFR Mutated Non-small Cell Lung Cancer Patients
Nuvectis Pharma, Inc.18 enrolled3 locationsNCT07315113
Recruiting
Phase 1
Study Targeting Myocardial Perfusion and Symptom Relief in Women With SGLT2 Inhibitors (STRONG)
Coronary microvascular diseaseCoronary Microvascular Dysfunction (CMD)Angina Patients With Non-obstructive Coronary Artery Disease
University of Virginia150 enrolled1 locationNCT06600178
Recruiting
Phase 1
Multiple Intracerebral Doses of Neural Stem Cell-Based Virotherapy (NSC-CRAd-S-pk7) for the Treatment of Recurrent High-Grade Gliomas
Currently Only Enrolling Glioblastoma Patients at First Recurrence
City of Hope Medical Center36 enrolled4 locationsNCT05139056
Recruiting
Phase 1Phase 2
Phase 1b/2a Randomized Double-blind Study to Investigate Safety Tolerability PK PD Preliminary Efficacy of Oral Administration of SNIPR001 in Patients With Hematologic Malignancy Scheduled for Allogeneic Hematopoietic Stem-Cell Transplant Receiving FQ Prophylaxis & Harboring FQR Ecoli Pre-Transplant
E Coli InfectionsAllogenic Transplant Patients
SNIPR Biome Aps.24 enrolled8 locationsNCT06938867
Recruiting
Phase 1
Phase I Study of XTL6001 Injection in Healthy and Obese Subjects
Weight Management in Adult Patients With Obesity or Overweight
Shanghai Xitaili Biomedicine Technology co., Ltd.80 enrolled1 locationNCT07205432
Recruiting
Phase 1Phase 2
An Advanced Decision Support Tool for Personalized Medicine for IVF Using Modeling and Optimization for Provera
Infertility (IVF Patients)
Urmila DIwekar200 enrolled2 locationsNCT07148999
Recruiting
Phase 1
A Clinical Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of [225Ac]Ac-PSMA-XT Injection in Patients With Metastatic Castration-resistant Prostate Cancer
Metastatic Castration-Resistant Prostate Cancer Patients
Xiaorong Sun40 enrolled1 locationNCT07135102
Recruiting
Phase 1
PM534 Administered Intravenously to Patients With Advanced Solid Tumors
Patients With Advanced Solid Tumors
PharmaMar30 enrolled3 locationsNCT05835609