Phase 1 Patient Clinical Trials
75 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 75 trials
Recruiting
Phase 1
TSL2109 Capsules in Advanced Solid Tumor Patients: Safety, Tolerability, PK and Preliminary Efficacy
Metastatic Castration-Resistant Prostate Cancer Patients
Tasly Pharmaceutical Group Co., Ltd78 enrolled1 locationNCT07514065
Recruiting
Phase 1
A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)
Metastatic Castration-resistant Prostate CancerMetastatic Castration-Resistant Prostate Cancer Patients
K36 Therapeutics, Inc.144 enrolled13 locationsNCT07103018
Recruiting
Phase 1
Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients
ObesitySmoking CessationBariatric Surgery Patients
Yale University20 enrolled1 locationNCT07224087
Recruiting
Phase 1
Trial of pTVG-HP+Nivo+Targeted Ablation of Resistant Lesions in Non-Castrate RecurrentOMPC
Prostate Cancer PatientsRecurrent Prostate CancerOligometastatic Prostate Cancer (OMPC)+1 more
University of Wisconsin, Madison14 enrolled1 locationNCT07090148
Recruiting
Phase 1Phase 2
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
Type 1 DiabetesType 1 Diabetes MellitusType 1 Diabetes Mellitis+7 more
COUR Pharmaceutical Development Company, Inc.72 enrolled31 locationsNCT06783309
Recruiting
Phase 1Phase 2
SNB-101 for Treatment of Extensive Stage Small Cell Lung Cancer
Patient is Not Suitable for Complete Surgical Resection With a Cytologically or Histologically Confirmed Small Cell Lung Cancer(SCLC)
SN BioScience55 enrolled1 locationNCT07391813
Recruiting
Phase 1
A Study Testing Topical Pain-Relieving Herbal Plasters in People Who Are Using Opioids for Their Pain
Cancer PainCancer PatientsSurvivor Patients
Memorial Sloan Kettering Cancer Center150 enrolled7 locationsNCT07447856
Recruiting
Phase 1Phase 2
Linaclotide for Colonoscopy Bowel Prep
Patients Scheduled for Colonoscopy
University of Florida10 enrolled1 locationNCT06692673
Recruiting
Phase 1Phase 2
Phase I/II Clinical Study of SHR-1501 Combined With Adbelizumab in Patients With Malignant Tumors
Patients With Advanced or Metastatic Malignant Tumors
Shanghai Hengrui Pharmaceutical Co., Ltd.203 enrolled1 locationNCT07073534
Recruiting
Phase 1
A Pharmacokinetic Study of TS-172 in Patients With Hepatic Impairment
Patients With Mild or Moderate Hepatic Impairment
Taisho Pharmaceutical Co., Ltd.24 enrolled1 locationNCT07231029
Recruiting
Phase 1
Study of NXP900 With Osimertinib in Subjects With Advanced, EGFR-Mutated Non-Small Cell Lung Cancer
EGFR Mutation Positive Non-small Cell Lung CancerEGFR Mutated Non-small Cell Lung Cancer Patients
Nuvectis Pharma, Inc.18 enrolled3 locationsNCT07315113
Recruiting
Phase 1
Study Targeting Myocardial Perfusion and Symptom Relief in Women With SGLT2 Inhibitors (STRONG)
Angina Patients With Non-obstructive Coronary Artery Disease
University of Virginia150 enrolled1 locationNCT06600178
Recruiting
Phase 1
Multiple Intracerebral Doses of Neural Stem Cell-Based Virotherapy (NSC-CRAd-S-pk7) for the Treatment of Recurrent High-Grade Gliomas
Currently Only Enrolling Glioblastoma Patients at First Recurrence
City of Hope Medical Center36 enrolled4 locationsNCT05139056
Recruiting
Phase 1Phase 2
Phase 1b/2a Randomized Double-blind Study to Investigate Safety Tolerability PK PD Preliminary Efficacy of Oral Administration of SNIPR001 in Patients With Hematologic Malignancy Scheduled for Allogeneic Hematopoietic Stem-Cell Transplant Receiving FQ Prophylaxis & Harboring FQR Ecoli Pre-Transplant
E Coli InfectionsAllogenic Transplant Patients
SNIPR Biome Aps.24 enrolled8 locationsNCT06938867
Recruiting
Phase 1
Phase I Study of XTL6001 Injection in Healthy and Obese Subjects
Weight Management in Adult Patients With Obesity or Overweight
Shanghai Xitaili Biomedicine Technology co., Ltd.80 enrolled1 locationNCT07205432
Recruiting
Phase 1Phase 2
An Advanced Decision Support Tool for Personalized Medicine for IVF Using Modeling and Optimization for Provera
Infertility (IVF Patients)
Urmila DIwekar200 enrolled2 locationsNCT07148999
Recruiting
Phase 1
A Clinical Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of [225Ac]Ac-PSMA-XT Injection in Patients With Metastatic Castration-resistant Prostate Cancer
Metastatic Castration-Resistant Prostate Cancer Patients
Xiaorong Sun40 enrolled1 locationNCT07135102
Recruiting
Phase 1
PM534 Administered Intravenously to Patients With Advanced Solid Tumors
Patients With Advanced Solid Tumors
PharmaMar30 enrolled3 locationsNCT05835609
Recruiting
Phase 1
Phase I Study of MT1011 Injection in Healthy Subjects
Used in Patients Receiving Anticoagulant Therapy (e.g., Rivaroxaban or Apixaban, Inhibitors of Coagulation Factor Xa) Who Require Reversal of Anticoagulation
Shaanxi Micot Pharmaceutical Technology Co., Ltd.40 enrolled1 locationNCT07024160
Recruiting
Phase 1
Hepatic Artery Transfusion of NKG2D CAR-NK Cells Followed by Intravenous Infusion of NKG2D CAR-T Cells to Treat Patients With Advanced Solid Tumors With Liver Metastases Who Have Failed Standard Treatments: a Phase I Exploratory Clinical Trial
Patients With Advanced Solid Tumors With Liver Metastases Who Have Failed Standard Treatments
Zhejiang University12 enrolled1 locationNCT07021534