Phase 4 Patient Clinical Trials

137 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 137 trials

Recruiting
Phase 4

Effect of Diosmin/Hesperidin Combination on Platinum Compounds-Induced Nephropathy in Cancer Patients

Cancer Patients
Beni-Suef University100 enrolled1 locationNCT07598214
Recruiting
Phase 4

Anrikefon-based Patient-controlled Intravenous Analgesia Following Laparoscopic Surgery

Laparoscopic SurgeryVisceral Pain, PostoperativeAnrikefon+1 more
Peking University First Hospital140 enrolled1 locationNCT07525986
Recruiting
Phase 4

Low-Dose Tenecteplase for Acute Ischemic Stroke Treatment in Aging Patients

Acute Ischemic Stroke Patients
Southwest Hospital, China798 enrolled49 locationsNCT07294209
Recruiting
Phase 4

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

Opioid UsePostoperative PainDepression+2 more
Texas Tech University Health Sciences Center90 enrolled2 locationsNCT06903819
Recruiting
Phase 4

The Intensive Care Platform Trial

Intensive care patientsCritical IllnessIntensive Care Unit Patients
Anders Perner10,000 enrolled21 locationsNCT06667999
Recruiting
Phase 4

Comparison Between Egyptian MTA, Biodentine Versus Calcium Hydroxide as Indirect Pulp Capping Materials In Permanent Teeth

Patient Reported Outcome MeasuresCalcium HydroxideDeep Caries+3 more
Cairo University35 enrolled1 locationNCT06683833
Recruiting
Phase 4

Pv-aCO₂ Gap-Guided Resuscitation in Adult Polytrauma Patients: A Prospective Randomized Controlled Trial

PolytraumaResuscitation, Trauma Patients
Pakistan Institute of Medical Sciences60 enrolled1 locationNCT07480655
Recruiting
Phase 4

Effect of Intraoperative Morphine on Postoperative Pain After CABG

Postoperative PainPain After SurgeryCardiac Surgery Patient
Istanbul University - Cerrahpasa60 enrolled1 locationNCT07472959
Recruiting
Phase 4

Effects of Donor-recipient Sex-matched Blood Transfusion on Patient Outcomes

CardiovascularRed Blood Cell TransfusionsSex Differences+3 more
Michelle Zeller11,082 enrolled8 locationsNCT06840756
Recruiting
Phase 4

Perineal Massage Using A Pelvic Wand During Pregnancy

Pelvic Floor DisordersPregnancy RelatedPatient Empowerment+1 more
Beth Israel Deaconess Medical Center140 enrolled1 locationNCT06986824
Recruiting
Phase 4

Anrikefon-based Patient-controlled Intravenous Analgesia After Laparoscopic Surgery

Laparoscopic SurgeryVisceral Pain, PostoperativeAnrikefon+1 more
Peking University First Hospital140 enrolled1 locationNCT07246785
Recruiting
Phase 4

Intrathecal Versus Epidural Morphine for Post-Cesarean Analgesia

Patient SatisfactionPost Operative PainAnalgesia+2 more
Hospital Central do Funchal120 enrolled1 locationNCT07386353
Recruiting
Phase 4

Actualities in Procedural Sedation: Remimazolam

ASA Class III/IV PatientsCOPD III/IVAge 65 and Older+1 more
Iuliu Hatieganu University of Medicine and Pharmacy200 enrolled1 locationNCT07362173
Recruiting
Phase 4

Ketorolac Use and Fresh Embryo Transfer Outcomes

Infertility (IVF Patients)Fresh Embryo TransferInfertility Treatment+2 more
Jessica D. Kresowik200 enrolled1 locationNCT07185724
Recruiting
Phase 4

Osteogenon in Orthopedics and Traumatology

Patients With Fractures
University of Opole150 enrolled1 locationNCT07210281
Recruiting
Phase 4

Sedation With Dexmedetomidine-esketamine Combination and Delirium in ICU Patients

Older PatientsEsketamineDexmedetomidine+3 more
Peking University First Hospital100 enrolled1 locationNCT07151716
Recruiting
Phase 4

Intrathecal Morphine for Postoperative Analgesia in Major Laparoscopic Abdominal Surgery, a IMPACT-Scope Trial

Patients Undergoing Major Laparoscopic Abdominal Surgery
First Affiliated Hospital, Sun Yat-Sen University700 enrolled1 locationNCT06666985
Recruiting
Phase 4

Comparative Efficacy of Rivaroxaban and Enoxaparin in Post-Laparotomy DVT Prevention

Deep Venous ThrombosesLaparotomy Patients
Mayo Hospital Lahore212 enrolled1 locationNCT07243080
Recruiting
Phase 4

SGLT2i Safety and Efficacy on Kidney Allograft Function in Non-diabetic Kidney Transplant Recipients

Randomized Controlled TrialKidney Transplantation RecipientsSodium-Glucose Transporter 2 Inhibitors+2 more
Odense University Hospital88 enrolled1 locationNCT07143773
Recruiting
Phase 4

Nausea and Vomiting in Postoperative Paediatric Patients With Patient-Controlled Analgesia (PCA): Morphine vs Oxycodone

Patient-controlled Analgesia
Murdoch Childrens Research Institute690 enrolled1 locationNCT06186141