Periodontitis, Adult Clinical Trials

7 recruitingLast updated: July 25, 2026

There are 7 actively recruiting periodontitis, adult clinical trials across 6 countries. Studies span Not Applicable, Phase 2. Top locations include Cleveland, Ohio, United States, Heidelberg, Baden-Wurttemberg, Germany, Jenjarum, Selangor, Malaysia. Updated daily from ClinicalTrials.gov.


Periodontitis, Adult Trials at a Glance

7 actively recruiting trials for periodontitis, adult are listed on ClinicalTrialsFinder across 6 cities in 6 countries. The largest study group is Not Applicable with 5 trials, with the heaviest enrollment activity in Cleveland, Heidelberg, and Jenjarum. Lead sponsors running periodontitis, adult studies include Mahsa University, Region Skane, and Case Western Reserve University.

Browse periodontitis, adult trials by phase

Treatments under study

About Periodontitis, Adult Clinical Trials

Looking for clinical trials for Periodontitis, Adult? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Periodontitis, Adult trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Periodontitis, Adult clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 17 of 7 trials

Recruiting
Not Applicable

HbA1c Screening in Dental Care and Primary Care Referral in Patients With Advanced Periodontitis

Prediabetes / Type 2 DiabetesPeriodontitis, Adult
Region Skane600 enrolled1 locationNCT07688278
Recruiting

Changes in Microbial Status From Dentate, Edentulous and After Dental Implant Placement

Microbial ColonizationPeriodontal DiseasesEdentulous Mouth+1 more
Case Western Reserve University12 enrolled1 locationNCT06149585
Recruiting
Not Applicable

Microbiological and Clinical Effects of Pre- and Probiotics in Non-Surgical Periodontal Therapy

Periodontitis (Stage 3)Periodontitis, AdultPeriodontitis Stage IV
University Hospital Heidelberg60 enrolled1 locationNCT07443410
Recruiting
Phase 2

3-Month Clinical Trial of Liquid S-PRF in Periodontal Debridement for Periodontitis Stages II-IV

Periodontitis Chronic Generalized ModeratePeriodontitisPeriodontitis (Stage 3)+6 more
Mahsa University14 enrolled1 locationNCT07293962
Recruiting
Not Applicable

The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness

MucositisDental ImplantationPeriodontitis, Adult+1 more
The University of Texas Health Science Center at San Antonio32 enrolled1 locationNCT07053969
Recruiting
Not Applicable

Full Mouth Ultrasonic Debridement Carried Out With Either Piezoelectric or Magnetostrictive Device

Periodontitis, Adult
University of Siena52 enrolled1 locationNCT06934291
Recruiting
Not Applicable

A Chitosan Brush and Enamel Matrix Derivative for Non-surgical Treatment of Furcations

Periodontitis, AdultFurcation DefectsFurcation of Root of Tooth+1 more
Riga Stradins University40 enrolled1 locationNCT06684769