Periodontal Diseases Clinical Trials

43 recruiting

Periodontal Diseases Trials at a Glance

49 actively recruiting trials for periodontal diseases are listed on ClinicalTrialsFinder across 6 cities in 21 countries. The largest study group is Not Applicable with 31 trials, with the heaviest enrollment activity in Izmir, London, and Birmingham. Lead sponsors running periodontal diseases studies include Izmir Katip Celebi University, Universidad de Murcia, and Case Western Reserve University.

Browse periodontal diseases trials by phase

Treatments under study

About Periodontal Diseases Clinical Trials

Looking for clinical trials for Periodontal Diseases? There are currently 43 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Periodontal Diseases trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Periodontal Diseases clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 49 trials

Recruiting
Phase 4

Antibiotics as Adjuncts to Periodontal Therapy:Pharmacokinetic Considerations and Dosing Strategies

AntibioticsPeriodontal DiseasesPharmacokinetics
University of Geneva, Switzerland45 enrolled1 locationNCT04669717
Recruiting

ORAL HYGIENE, PERIODONTAL STATUS AND QUALITY OF LIFE

GingivitisPeriodontal DiseasesPeriodontitis
Abant Izzet Baysal University160 enrolled1 locationNCT07530978
Recruiting

Association Between Periodontal Status and the Prevalence of Entamoeba Gingivalis and Trichomonas Tenax

PeriodontitisGingivitis and Periodontal Diseases
Abant Izzet Baysal University120 enrolled1 locationNCT07551115
Recruiting

Characterization of JAK1 and JAK2 Activation in Gingival Tissues During Homeostasis and Periodontitis

Periodontal DiseasesPeriodontitis
University of Chile30 enrolled1 locationNCT07536204
Recruiting
Not Applicable

NOVOSYN® Quick Versus MONOSYN® Quick Suture Material in Resective Periodontal Surgery

GingivitisPeriodontal DiseasesGingival Diseases
Aesculap AG84 enrolled1 locationNCT05813236
Recruiting
Not Applicable

Evaluation of Toothbrush Bristles

Gingivitis and Periodontal Diseases
State University of New York at Buffalo70 enrolled1 locationNCT07306026
Recruiting
Not Applicable

Evaluation Of The Efficacy Of Subgingival Application Of Lovastatin Gel As An Adjunct To Non-Surgical Treatment Of Periodontitis In Generally Healthy Smokers And Non-Smokers Patients in Central Europe.

Periodontal DiseasesPeriodontitisPeriodontal Disease+1 more
Medical University of Silesia44 enrolled1 locationNCT07282756
Recruiting
Not Applicable

NIPSA Versus Marginal Approach by Palatal Incision and MIST in Periodontal Regeneration

Periodontal DiseasesPeriodontitisPeriodontal Pocket
Universidad de Murcia60 enrolled1 locationNCT03997552
Recruiting
Not Applicable

Periodontal Granulation Tissue Preservation in Surgical Periodontitis Treatment

Periodontal DiseasesPeriodontal PocketPeriodontal Bone Loss
Universidad de Murcia25 enrolled1 locationNCT05533528
Recruiting
Not Applicable

Effectiveness of Intraseptal Anesthesia for Periodontal Surgical Procedures

PeriodontitisGingivitis and Periodontal Diseases
University of Belgrade60 enrolled1 locationNCT07212270
Recruiting

Periodontal Status and Disease Severity in Pemphigus Vulgaris Patients

Periodontal DiseasesPemphigus Vulgaris (PV)
Saglik Bilimleri Universitesi20 enrolled1 locationNCT07384221
Recruiting
Not Applicable

F.L.O.S.S. Project (Facilitated Lessons on Oral and Systemic Health in Survivors)

CancerOral MucositisPeriodontal Diseases
Georgetown University100 enrolled1 locationNCT06315855
Recruiting

HALP Score, Blood-Based Inflammatory Indices, and Salivary MMP-8 in Periodontal Disease and Healing After Non-Surgical Therapy

Periodontal DiseasesPeriodontitisGingivitis; Chronic
Ömer Faruk Okumuş180 enrolled1 locationNCT07312045
Recruiting
Not Applicable

Periodontal Health and Sodium Bicarbonate Toothpaste

Periodontal Diseases
University of Plymouth100 enrolled1 locationNCT07274189
Recruiting
Not Applicable

Novel Dental Gel as an Adjunct to Scaling and Root Planing

Plaque, DentalPeriodontal DiseasesGingival Diseases+2 more
University of Alabama at Birmingham76 enrolled1 locationNCT05384132
Recruiting

The Role of Granulation Tissue in Periodontal Regeneration

Periodontal DiseasesPeriodontitisPeriodontal Disease+5 more
Riga Stradins University46 enrolled1 locationNCT07254117
Recruiting
Not Applicable

Interdental Hygiene Methods in Young Adults

Oral HygienePeriodontal DiseasesMicrobiota-related Disease
Hospices Civils de Lyon55 enrolled1 locationNCT06848790
Recruiting
Not Applicable

Microsurgery and Periodontal Healing

Periodontal Diseases
The University of Texas Health Science Center at San Antonio25 enrolled1 locationNCT07054008
Recruiting
Not Applicable

Oral Health Intervention in Adult Primary Care

Dry MouthPeriodontal DiseasesDental Caries+1 more
Case Western Reserve University929 enrolled1 locationNCT06555029
Recruiting
Not Applicable

Treatment of Periodontal Intra-bony Defects With a Volume Stable Collagen Matrix or Deproteinized Bovine Bone Mineral With 10% Collagen

Periodontal Diseases
University of Bern80 enrolled1 locationNCT06676826