Physiology Clinical Trials

50 recruitingLast updated: May 13, 2026

There are 50 actively recruiting physiology clinical trials across 13 countries. Studies span Not Applicable, Early Phase 1, Phase 1. Top locations include Bethesda, Maryland, United States, Baltimore, Maryland, United States, Copenhagen, Denmark. Updated daily from ClinicalTrials.gov.


Physiology Trials at a Glance

50 actively recruiting trials for physiology are listed on ClinicalTrialsFinder across 6 cities in 13 countries. The largest study group is Not Applicable with 21 trials, with the heaviest enrollment activity in Bethesda, Baltimore, and Copenhagen. Lead sponsors running physiology studies include National Institute of Neurological Disorders and Stroke (NINDS), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), and National Center for Complementary and Integrative Health (NCCIH).

Browse physiology trials by phase

Treatments under study

About Physiology Clinical Trials

Looking for clinical trials for Physiology? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Physiology trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Physiology clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 50 trials

Recruiting
Not Applicable

The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure

ObesityHealthy VolunteersNormal Physiology
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)120 enrolled1 locationNCT05545306
Recruiting

A Natural History Study of Metabolic Sizing in Health and Disease

CancerDiabetesChronic Kidney Disease+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)2,000 enrolled1 locationNCT05398783
Recruiting
Not Applicable

Defining Neurobiological Links Between Substance Use and Mental Illness

Substance Use DisorderNormal PhysiologyMajor Depressive Disorder
National Institute on Drug Abuse (NIDA)620 enrolled1 locationNCT05538910
Recruiting
Early Phase 1

Developing Transcranial Neuromodulation Protocols for Learning and Decision-Making

Normal Physiology
National Institute on Drug Abuse (NIDA)600 enrolled1 locationNCT06561828
Recruiting

Clinical and Scientific Assessment of Pain and Painful Disorders

PainNormal Physiology
National Center for Complementary and Integrative Health (NCCIH)10,000 enrolled1 locationNCT02707029
Recruiting
Not Applicable

Development Of Neuroimaging Methods To Assess The Neurobiology Of Addiction

Normal Physiology
National Institute on Alcohol Abuse and Alcoholism (NIAAA)192 enrolled1 locationNCT02535702
Recruiting

Investigating the Impact of Obesity on Pubertal Development in Girls

ObesityNormal PhysiologyPuberty
National Institute of Environmental Health Sciences (NIEHS)150 enrolled1 locationNCT02583646
Recruiting

Development of 3T Magnetic Resonance Research Methods for NIA Studies

Normal Physiology
National Institute on Aging (NIA)1,000 enrolled1 locationNCT01324206
Recruiting

Perception, Sensation, Cognition and Action in Humans

Normal Physiology
National Eye Institute (NEI)10,200 enrolled2 locationsNCT03407066
Recruiting

Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants

Sickle Cell DiseaseMalariaAlpha and Beta Thalassemia+1 more
National Institute of Allergy and Infectious Diseases (NIAID)300 enrolled1 locationNCT03937817
Recruiting
Not Applicable

Assessment of the Relationship Between Cerebral Blood Flow and Heart Rate

Cerebrovascular CirculationPhysiology
University of Calgary20 enrolled1 locationNCT04391465
Recruiting

Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging

Normal and Abnormal Cardiovascular Physiology
National Heart, Lung, and Blood Institute (NHLBI)5,000 enrolled1 locationNCT03581318
Recruiting

Assessing and Improving Quantitative Magnetic Resonance Imaging Metrics in Human Subjects

Normal Physiology
National Institute of Neurological Disorders and Stroke (NINDS)200 enrolled1 locationNCT05604534
Recruiting
Not Applicable

Sociocultural & Biobehavioral Influences on Pain Expression and Assessment

PainHealthy VolunteersNormal Physiology
National Center for Complementary and Integrative Health (NCCIH)700 enrolled1 locationNCT03258580
Recruiting

Functional Magnetic Resonance Imaging Sleep Study With Auditory Stimuli

Normal Physiology
National Institute of Neurological Disorders and Stroke (NINDS)2,378 enrolled1 locationNCT02629107
Recruiting

Influence of Brain Oscillation-Dependent TMS on Motor Function

HealthyStrokeNormal Physiology+1 more
National Institute of Neurological Disorders and Stroke (NINDS)114 enrolled1 locationNCT03288220
Recruiting

Investigational Use of Neuromuscular Ultrasound

Peripheral NeuropathyNormal PhysiologyMuscular Dystrophy+1 more
National Institute of Neurological Disorders and Stroke (NINDS)150 enrolled1 locationNCT05237973
Recruiting
Not Applicable

MRS Measurement of Glutamate and GABA Metabolism in Brain

Normal Physiology
National Institute of Mental Health (NIMH)200 enrolled1 locationNCT00109174
Recruiting
Not Applicable

Smartphone-based Cognitive Emotion Regulation Training for Unpaid Primary Caregivers of Persons With Alzheimer's Disease

PsychologicalStressEmotions+3 more
Bryan Denny270 enrolled1 locationNCT05949047
Recruiting

Development and Validation of Learning and Decision-Making Tasks

Normal Physiology
National Institute on Drug Abuse (NIDA)550 enrolled1 locationNCT05707806