Physiology Clinical Trials

2 recruiting

Frequently Asked Questions

Common questions about Physiology clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 50 trials

Recruiting
Early Phase 1

Developing Transcranial Neuromodulation Protocols for Learning and Decision-Making

Normal Physiology
National Institute on Drug Abuse (NIDA)600 enrolled1 locationNCT06561828
Recruiting

Assessing and Improving Quantitative Magnetic Resonance Imaging Metrics in Human Subjects

Normal Physiology
National Institute of Neurological Disorders and Stroke (NINDS)200 enrolled1 locationNCT05604534
Recruiting

Perception, Sensation, Cognition and Action in Humans

Normal Physiology
National Eye Institute (NEI)10,200 enrolled2 locationsNCT03407066
Recruiting
Not Applicable

Development Of Neuroimaging Methods To Assess The Neurobiology Of Addiction

Normal Physiology
National Institute on Alcohol Abuse and Alcoholism (NIAAA)192 enrolled1 locationNCT02535702
Recruiting

Functional Magnetic Resonance Imaging Sleep Study With Auditory Stimuli

Normal Physiology
National Institute of Neurological Disorders and Stroke (NINDS)2,378 enrolled1 locationNCT02629107
Recruiting
Not Applicable

Sociocultural & Biobehavioral Influences on Pain Expression and Assessment

PainHealthy VolunteersNormal Physiology
National Center for Complementary and Integrative Health (NCCIH)700 enrolled1 locationNCT03258580
Recruiting
Not Applicable

MRS Measurement of Glutamate and GABA Metabolism in Brain

Normal Physiology
National Institute of Mental Health (NIMH)200 enrolled1 locationNCT00109174
Recruiting

Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants

Sickle Cell DiseaseMalariaAlpha and Beta Thalassemia+1 more
National Institute of Allergy and Infectious Diseases (NIAID)300 enrolled1 locationNCT03937817
Recruiting

Development of 3T Magnetic Resonance Research Methods for NIA Studies

Normal Physiology
National Institute on Aging (NIA)1,000 enrolled1 locationNCT01324206
Recruiting

Development and Validation of Learning and Decision-Making Tasks

Normal Physiology
National Institute on Drug Abuse (NIDA)550 enrolled1 locationNCT05707806
Recruiting
Not Applicable

Defining Neurobiological Links Between Substance Use and Mental Illness

Substance Use DisorderNormal PhysiologyMajor Depressive Disorder
National Institute on Drug Abuse (NIDA)620 enrolled1 locationNCT05538910
Recruiting

Investigating the Impact of Obesity on Pubertal Development in Girls

ObesityNormal PhysiologyPuberty
National Institute of Environmental Health Sciences (NIEHS)150 enrolled1 locationNCT02583646
Recruiting

Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging

Normal and Abnormal Cardiovascular Physiology
National Heart, Lung, and Blood Institute (NHLBI)5,000 enrolled1 locationNCT03581318
Recruiting
Phase 1

Pharmacokinetic Study of Single-Dose Modified Release Glipizide in Healthy Volunteers

Human Gastrointestinal Physiology Data
University of Michigan40 enrolled1 locationNCT05159427
Recruiting

Mobilization and Outcomes After Venous Closure

Electrophysiology StudyVenous Vascular Closure
Cordis US Corp.300 enrolled3 locationsNCT07246902
Recruiting

Investigational Use of Neuromuscular Ultrasound

Peripheral NeuropathyNormal PhysiologyMuscular Dystrophy+1 more
National Institute of Neurological Disorders and Stroke (NINDS)150 enrolled1 locationNCT05237973
Recruiting

Influence of Brain Oscillation-Dependent TMS on Motor Function

HealthyStrokeNormal Physiology+1 more
National Institute of Neurological Disorders and Stroke (NINDS)114 enrolled1 locationNCT03288220
Recruiting
Not Applicable

Neural and Psychological Mechanisms of Pain Perception

PainHealthy VolunteersNormal Physiology
National Center for Complementary and Integrative Health (NCCIH)500 enrolled1 locationNCT02446262
Recruiting

Molecular, Cellular, and Genetic Characterization of Human Adipose Tissue and Its Role in Metabolism

Brown Adipose Tissue (BAT) PhysiologyPhenotypingBrown Adipocytes
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)300 enrolled1 locationNCT02692885
Recruiting
Not Applicable

IVUS-FFR Accuracy for Coronary Stenosis

Percutaneous Coronary InterventionIntravenous UltrasoundCoronary Physiology
China National Center for Cardiovascular Diseases292 enrolled1 locationNCT07446023