Pleural Effusions Clinical Trials

8 recruitingLast updated: June 18, 2026

There are 8 actively recruiting pleural effusions clinical trials across 6 countries. Studies span Not Applicable, Phase 1, Phase 2. Top locations include Barcelona, Spain, Beijing, Beijing Municipality, China, Beijing, China. Updated daily from ClinicalTrials.gov.


Pleural Effusions Trials at a Glance

8 actively recruiting trials for pleural effusions are listed on ClinicalTrialsFinder across 6 cities in 6 countries. The largest study group is Not Applicable with 3 trials, with the heaviest enrollment activity in Barcelona, Beijing, and Beijing. Lead sponsors running pleural effusions studies include Cambridge University Hospitals NHS Foundation Trust, Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau, and Beth Israel Deaconess Medical Center.

Browse pleural effusions trials by phase

Treatments under study

About Pleural Effusions Clinical Trials

Looking for clinical trials for Pleural Effusions? There are currently 3 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Pleural Effusions trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Pleural Effusions clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 18 of 8 trials

Recruiting

EX VIVO DRUG RESPONSE PROFILING AND OUTCOME PREDICTION IN LUNG ADENOCARCINOMA

Lung AdenocarcinomaMalignant Pleural Effusions (Mpe)
Sheba Medical Center400 enrolled1 locationNCT07636252
Recruiting
Phase 1Phase 2

First-in-Human Expanded Cohort Study of Intrapleural Administration of TolueneSulfonamide in Patients With Malignant Pleural Effusion

Non-small Cell Lung CancerMalignant Pleural Effusions (Mpe)
Gang Hou105 enrolled1 locationNCT07332858
Recruiting
Phase 1Phase 2

A Phase Ib/II Clinical Trial of M701 in the Treatment of Malignant Pleural Effusions Caused by NSCLC

NSCLC Stage IVMalignant Pleural Effusions
Wuhan YZY Biopharma Co., Ltd.96 enrolled1 locationNCT05543330
Recruiting
Not Applicable

Impact of Pleural Manometry on the Assessment and Treatment of Malignant Pleural Effusion: A Pilot Clinical Trial

Malignant Pleural Effusions (Mpe)
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau95 enrolled1 locationNCT07120867
Recruiting
Phase 2

Evaluating the Efficacy and Safety of Saline Irrigation as an Add-On Therapy for Retained Pleural Infections [LYTICS +]

Pleural EffusionsPleural Effusion DisorderPleural Effusion Associated With Pulmonary Infection
Beth Israel Deaconess Medical Center96 enrolled1 locationNCT06713382
Recruiting
Not Applicable

ARMSTRONG - Air entRainMent vS sTandard tReatment in nOn-expandable luNG

Non-expandable LungTrapped LungPleural Effusion+1 more
Cambridge University Hospitals NHS Foundation Trust41 enrolled1 locationNCT06959719
Recruiting
Not Applicable

Drainage Of Pleural Effusions in the Intensive Care Unit (DOPE-ICU) - Feasibility Trial

Pleural EffusionsRespiratory Failure
Olav Schjørring88 enrolled6 locationsNCT06709456
Recruiting
Phase 1

A Phase Ib Study of JMKX000197 Injection in the Treatment of Malignant Pleural Effusion

Malignant Pleural Effusions (Mpe)
Jemincare30 enrolled1 locationNCT06740019