RecruitingNot ApplicableNCT06709456

Drainage Of Pleural Effusions in the Intensive Care Unit (DOPE-ICU) - Feasibility Trial

Drainage of Pleural Effusions in the Intensive Care Unit in Adults With Respiratory Failure: A Randomised Clinical Feasibility Trial of Performing Versus Withholding Pleural Drainage

Sponsor

Olav Schjørring

Enrollment

88 participants

Start Date

Dec 2, 2024

Study Type

INTERVENTIONAL

Conditions

Pleural Effusions Respiratory Failure

Summary

This trial evaluates the feasibility of ultrasound-guided pleural drainage versus no drainage in adult ICU patients with pleural effusions (fluid buildup around the lungs) and respiratory failure. Half of the patients will undergo drainage, while the other half will not unless their condition worsens to a prespecified degree. Outcomes include feasibility measures, clinical parameters, mortality, serious adverse events, and life support use over 90 days.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Ultrasonography-guided pleural drainage for people with pleural effusions and respiratory failure. The study is currently recruiting participants at 6 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREUltrasonography-guided pleural drainage

Ultrasonography-guided pleural drainage with insertion of a small-bore intrapleural catheter. Contralateral and repeated drainage conducted as specified during ICU stay until day 90.

Locations(6)

Department of Anaesthesia and Intensive Care, Aalborg University Hospital

Aalborg, Denmark

ICU department 4131, Copenhagen University Hospital, Rigshospitalet

Copenhagen, Denmark

Department of Anaesthesia and Intensive Care, Nordsjællands Hospital, University of Copenhagen, Hillerød

Hillerød, Denmark

Department of Anaesthesiology and Intensive Care Medicine, Sygehus Lillebælt, Kolding

Kolding, Denmark

Department of Anaesthesia and Intensive Care, Zealand University Hospital, Køge

Køge, Denmark

Department of Anaesthesia and Intensive Care, Zealand University Hospital, Roskilde

Roskilde, Denmark

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NCT06709456

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