Phase 3 Postoperative Clinical Trials
49 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 49 trials
Recruiting
Phase 3
Opioid-Free Orthopaedics
PainPain, Postoperative
Emory University80 enrolled3 locationsNCT04659317
Recruiting
Phase 3
Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression
Opioid UsePain, PostoperativePain, Back+1 more
Hospital for Special Surgery, New York150 enrolled1 locationNCT05058287
Recruiting
Phase 3
RADA16 for Adult Tonsillectomy
Postoperative Pain
Rutgers, The State University of New Jersey134 enrolled2 locationsNCT07060495
Recruiting
Phase 3
Postoperative Radiotherapy Combined With Nimotuzumab Followed by Benmelstobart in High-Risk Patients With Head and Neck Squamous Cell Carcinoma
Head & Neck CancerPostoperative Adjuvant TreatmentHead & Neck Squamous Cell Carcinoma
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University370 enrolled1 locationNCT07445048
Recruiting
Phase 2Phase 3
Exploring the Impact of Genetic Variations on The Clinical Efficacy of Nalbuphine in Postoperative Pain Management
Open Colorectal SurgeryAppendectomyPostoperative Pain+5 more
Dr. Asma Abdus Salam263 enrolled1 locationNCT06996561
Recruiting
Phase 3
The SCOPE Trial: Sleep, Cognition, and Pain Bundle vs. ERAS-cardiac for Postoperative Delirium
Delirium - PostoperativeDelirium in Old Age
Beth Israel Deaconess Medical Center406 enrolled3 locationsNCT06721819
Recruiting
Phase 3
Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Surgery: A Randomized Double-Blind Controlled Clinical Trial
Postoperative Pain
Oman Ministry of Health138 enrolled1 locationNCT07413055
Recruiting
Phase 3
Adding Aprepitant to a Multimodal Strategy for the Prevention of Postoperative Nausea and Vomiting in High-risk Outpatient Surgical Patients
PreventionNausea and Vomiting, Postoperative
Centre hospitalier de l'Université de Montréal (CHUM)260 enrolled1 locationNCT07248280
Recruiting
Phase 3
Robotic Opioid-free Prostatectomy Enhanced Strategy (ROPES)
Prostate CancerOpioid Consumption, PostoperativeMultimodal Analgesia+2 more
Brigham and Women's Hospital300 enrolled2 locationsNCT07427043
Recruiting
Phase 3
A Clinical Trial Evaluating the Efficacy and Safety of HSK21542 in Patients for Postoperative Pain Treatment in Orthopedic Surgery
Postoperative Pain Management
Haisco Pharmaceutical Group Co., Ltd.405 enrolled2 locationsNCT07186426
Recruiting
Phase 3
Pancreatic Head Resection or Total Pancreatectomy With Islet Autotransplantation in Patients With Periampullary Cancer and High Risk Profile for the Development of Postoperative Pancreatic Fistula
Periampullary CancerPostoperative Pancreatic Fistula
Technische Universität Dresden32 enrolled1 locationNCT05843877
Recruiting
Phase 3
Suzetrigine in Total Hip Arthroplasty
Total Hip Replacement SurgeryPainPain Management+13 more
Hospital for Special Surgery, New York210 enrolled1 locationNCT07226700
Recruiting
Phase 3
PF614 Analgesic Activity in Acute Postoperative Pain (PF614-301)
Postoperative Pain, Acute
Ensysce Biosciences320 enrolled3 locationsNCT06602271
Recruiting
Phase 2Phase 3
Pyridostigmine Efficacy and Safety for Treatment of Ileus After Colorectal Surgery
Postoperative Ileus
Stefan Holubar MD MS FACS, FASCRS50 enrolled1 locationNCT05334485
Recruiting
Phase 3
Post-Operative Urinary Retention on Revision Knee Arthroplasty: the Role of Intrathecal Morphine
Nerve BlockAnesthesia, SpinalArthroplasties, Knee Replacement+1 more
University of Toronto50 enrolled1 locationNCT07050277
Recruiting
Phase 3
A Study of TLC590 for Postsurgical Pain Following Bunionectomy
Postoperative Pain
TLC Biopharmaceuticals, Inc.300 enrolled4 locationsNCT07222748
Recruiting
Phase 3
Analgesic Efficacy of Different Liposomal Bupivacaine Doses in the Adductor Canal Block for Total Knee Arthroplasty
Pain, PostoperativeTotal Knee ArthroplastyLiposomal Bupivacaine+2 more
The University of Hong Kong177 enrolled1 locationNCT06740214
Recruiting
Phase 3
The Effect of Discontinuation of Renin Angiotensin System Inhibitors on the Perioperative Myocardial Injury in Adult Patients Undergoing Colorectal Cancer Surgery
Perioperative/Postoperative ComplicationsMyocardium; InjuryAngiotensin-Converting-Enzyme Inhibitor
Kasr El Aini Hospital156 enrolled1 locationNCT06862115
Recruiting
Phase 3
Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN)
Breast CancerPain, ChronicPost-mastectomy Pain Syndrome+1 more
University Health Network, Toronto1,602 enrolled17 locationsNCT04874038
Recruiting
Phase 2Phase 3
A Phase Ⅱ/Ⅲ Study of HRS-2129 for Postsurgical Pain Management in Abdominal Surgery
postoperative analgesia
Shandong Suncadia Medicine Co., Ltd.360 enrolled2 locationsNCT07185594