Phase 4 Postoperative Clinical Trials

127 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 127 trials

Recruiting
Phase 4

Methadone for Post-operative Spine Surgery

Pain, Postoperative
Brandon Knopp30 enrolled1 locationNCT07517679
Recruiting
Phase 4

Efficacy of Preventive Ketamine on Postoperative Pain

Postoperative Pain
Ain Shams University90 enrolled1 locationNCT04908579
Recruiting
Phase 4

Precision Pain Management - A Randomized Clinical Trial Assessing the Efficacy of Suzetrigine on Postoperative Analgesia Among Surgical Patients at Higher Risk for Persistent Postoperative Opioid Use (POU)

Opioid Consumption, Postoperative
University of California, San Diego100 enrolled1 locationNCT07672015
Recruiting
Phase 4

Bupivacaine Liposomes or Bupivacaine for CMB on Postoperative Analgesia in Laparoscopic Hepatobiliary Pancreatic Surgery

Analgesia, PostoperativeBupivacaineOpioids+1 more
Huazhong University of Science and Technology60 enrolled2 locationsNCT06737341
Recruiting
Phase 4

Uroselective Alpha-1-Antagonist to Reduce the Incidence and Duration of Postoperative Urinary Retention Following Spine Surgery

Urinary Retention Postoperative
Mayo Clinic20 enrolled1 locationNCT07174349
Recruiting
Phase 4

Comparison of Intraperitoneal Bupivacaine and Saline Irrigation for Pain Relief After Laparoscopic Cholecystectomy

Postoperative Pain
Wah Medical college , POF hospital106 enrolled1 locationNCT07650760
Recruiting
Phase 4

Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm Repair

Opioid UsePostoperative PainAnesthesia+5 more
University of Crete40 enrolled1 locationNCT04894864
Recruiting
Phase 4

Liposomal Bupivacaine Versus Plain Bupivacaine After Intercostal Injections For Pain Management After Thoracoscopy

Pain, PostoperativePharmacokinetics
Milton S. Hershey Medical Center40 enrolled1 locationNCT03737292
Recruiting
Phase 4

Intrathecal Morphine for Analgesia in Video-assisted and Robotic-assisted Thoracic Surgery

Pain, Postoperative
Northwestern University90 enrolled1 locationNCT05351229
Recruiting
Phase 4

The Effect of Different Types of Mouthwash on Extraction Sockets' Healing

Quality of LifePostoperative ComplicationsExtraction Socket Healing
University of Jordan100 enrolled1 locationNCT06587880
Recruiting
Phase 4

The Effect of Zolpidem on Outcomes Following Lumbar Spine Fusion

Pain, PostoperativeSpine FusionLumbar Spine Degeneration+1 more
University of Southern California140 enrolled1 locationNCT05746143
Recruiting
Phase 4

Ginger to Prevent Nausea and Vomiting After Laparoscopic Cholecystectomy

Postoperative nausea and vomitingLaparoscopic Cholecystectomy
University Tunis El Manar102 enrolled1 locationNCT07190495
Recruiting
Phase 4

Effects of Ciprofol on Postoperative Delirium and Outcomes in Elderly Patients Undergoing Major Thoracic Surgery

Postoperative Delirium (POD)
Wang Tianlong214 enrolled9 locationsNCT06674226
Recruiting
Phase 4

Anrikefon-based Patient-controlled Intravenous Analgesia Following Laparoscopic Surgery

Laparoscopic SurgeryVisceral Pain, PostoperativeAnrikefon+1 more
Peking University First Hospital140 enrolled1 locationNCT07525986
Recruiting
Phase 4

PECS Study for CIED Implantation Surgery

Pain, PostoperativeAdolescentChild
The Hospital for Sick Children48 enrolled1 locationNCT04577690
Recruiting
Phase 4

Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial

SurgeryPain, Postoperative
University of Michigan900 enrolled8 locationsNCT05722002
Recruiting
Phase 4

Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery

PainCleft PalatePerioperative Care+2 more
Duke University60 enrolled1 locationNCT06962306
Recruiting
Phase 4

Intranasal Dexmedetomidine-esketamine Administration and Postoperative Pain in Pediatric Patients

Postoperative PainEsketamineDexmedetomidine+3 more
Peking University First Hospital160 enrolled1 locationNCT07479602
Recruiting
Phase 4

The Effect of Nocturnal Dexmedetomidine on Postoperative Sleep Quality and Fatigue After Major Surgery in Elderly Patients: DEXSLEEP Study

surgical stress responsePostoperative FatiguePostoperative Sleep Disturbances
Ziekenhuis Oost-Limburg102 enrolled1 locationNCT06480539
Recruiting
Phase 4

The Effect of Corticosteroids on Quality of Life Following Total Hip Arthroplasty: HIPSTER Study

Quality of LifeHealth-related Quality of LifePostoperative Quality of Recovery
Ziekenhuis Oost-Limburg224 enrolled2 locationsNCT07378215