Phase 4 Postoperative Clinical Trials

123 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 123 trials

Recruiting
Phase 4

The Effect of Different Types of Mouthwash on Extraction Sockets' Healing

Quality of LifePostoperative ComplicationsExtraction Socket Healing
University of Jordan100 enrolled1 locationNCT06587880
Recruiting
Phase 4

The Effect of Zolpidem on Outcomes Following Lumbar Spine Fusion

Pain, PostoperativeSpine FusionLumbar Spine Degeneration+1 more
University of Southern California140 enrolled1 locationNCT05746143
Recruiting
Phase 4

Ginger to Prevent Nausea and Vomiting After Laparoscopic Cholecystectomy

Postoperative nausea and vomitingLaparoscopic Cholecystectomy
University Tunis El Manar102 enrolled1 locationNCT07190495
Recruiting
Phase 4

Effects of Ciprofol on Postoperative Delirium and Outcomes in Elderly Patients Undergoing Major Thoracic Surgery

Postoperative Delirium (POD)
Wang Tianlong214 enrolled9 locationsNCT06674226
Recruiting
Phase 4

Anrikefon-based Patient-controlled Intravenous Analgesia Following Laparoscopic Surgery

Laparoscopic SurgeryVisceral Pain, PostoperativeAnrikefon+1 more
Peking University First Hospital140 enrolled1 locationNCT07525986
Recruiting
Phase 4

PECS Study for CIED Implantation Surgery

Pain, PostoperativeAdolescentChild
The Hospital for Sick Children48 enrolled1 locationNCT04577690
Recruiting
Phase 4

Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial

SurgeryPain, Postoperative
University of Michigan900 enrolled8 locationsNCT05722002
Recruiting
Phase 4

Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery

PainCleft PalatePerioperative Care+2 more
Duke University60 enrolled1 locationNCT06962306
Recruiting
Phase 4

Intranasal Dexmedetomidine-esketamine Administration and Postoperative Pain in Pediatric Patients

Postoperative PainEsketamineDexmedetomidine+3 more
Peking University First Hospital160 enrolled1 locationNCT07479602
Recruiting
Phase 4

The Effect of Corticosteroids on Quality of Life Following Total Hip Arthroplasty: HIPSTER Study

Quality of LifeHealth-related Quality of LifePostoperative Quality of Recovery
Ziekenhuis Oost-Limburg224 enrolled2 locationsNCT07378215
Recruiting
Phase 4

The Effect of Nocturnal Dexmedetomidine on Postoperative Sleep Quality and Fatigue After Major Surgery in Elderly Patients: DEXSLEEP Study

surgical stress responsePostoperative FatiguePostoperative Sleep Disturbances
Ziekenhuis Oost-Limburg102 enrolled1 locationNCT06480539
Recruiting
Phase 4

Sore Throat After Open Neck Elective Surgery

Postoperative Sore Throat, Cough, HoarsenessThyroid and Parathyroid Surgery
Saint Petersburg State University, Russia764 enrolled1 locationNCT07124650
Recruiting
Phase 4

Intraperitoneal Infusion of Analgesic for Postoperative Pain Management

Pain, PostoperativeGynecologic Surgical ProceduresHysterectomy+1 more
Ying Liu120 enrolled2 locationsNCT04130464
Recruiting
Phase 4

Uroselective Alpha-1-Antagonist to Reduce the Incidence and Duration of Postoperative Urinary Retention Following Spine Surgery

Urinary Retention Postoperative
Mayo Clinic20 enrolled1 locationNCT07174349
Recruiting
Phase 4

Efficacy and Safety of Anrikefon for Postoperative Analgesia in Ophthalmic Surgery

Opioid analgesiaPostoperative Pain ManagementOphthalmic Surgery
Zhongshan Ophthalmic Center, Sun Yat-sen University204 enrolled3 locationsNCT07269106
Recruiting
Phase 4

Efficacy of Preventive Ketamine on Postoperative Pain

Postoperative Pain
Ain Shams University90 enrolled1 locationNCT04908579
Recruiting
Phase 4

Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia

Pain, Postoperative
Boston University75 enrolled1 locationNCT06757075
Recruiting
Phase 4

Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery

Opioid analgesiaPain, PostoperativeOpioid-use Disorder+2 more
Jenna-Leigh Wilson100 enrolled1 locationNCT06949826
Recruiting
Phase 4

Suprainguinal Fascia Iliaca Block With vs Without Dexmedetomidine

Postoperative Pain Management
Rhode Island Hospital120 enrolled1 locationNCT07316166
Recruiting
Phase 4

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

Opioid UsePostoperative PainDepression+2 more
Texas Tech University Health Sciences Center90 enrolled2 locationsNCT06903819