RecruitingPhase 4NCT07221617

Oral Methadone in Cardiac Surgery

Oral Methadone In Cardiac Surgery

Sponsor

Mayo Clinic

Enrollment

100 participants

Start Date

Jan 13, 2026

Study Type

INTERVENTIONAL

Conditions

Pain, Postoperative Anesthesia Cardiac Surgery

Summary

The purpose of this study is to compare the effects of administration of oral methadone preoperatively and intravenous methadone upon induction of general anesthesia on postoperative pain for patients undergoing elective cardiac surgery.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Methadone, intravenously and a drug called Methadone, oral for people with anesthesia, cardiac surgery, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGMethadone, oral

Patients will receive 0.4mg/kg PO methadone immediately prior to transport to the operating room

DRUGMethadone, intravenously

Patients will receive 0.3mg/kg methadone intravenously after induction of general anesthesia

Locations(1)

Mayo Clinic in Rochester

Rochester, Minnesota, United States

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NCT07221617

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