Phase 1 Preeclampsia Clinical Trials

9 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 19 of 9 trials

Recruiting
Phase 1

A Study to Investigate the Safety, Pharmacodynamic and Pharmacokinetic Characteristics of CBP-4888 in Hospitalized Participants With Preterm Preeclampsia and Their Children up to 24 Months

PreeclampsiasFlt1 Mediated Preterm PreeclampsiaPreterm Preeclampsia
Comanche Biopharma60 enrolled2 locationsNCT07282171
Not Yet Recruiting
Phase 1

A study to investigate the safety, pharmacodynamic and pharmacokinetic characteristics of CBP-4888 in hospitalized participants with preterm preeclampsia and the safety and tolerability of CBP-4888 on their children.

Pre-term preeclampsia
Comanche Biopharma (AU) Pty Ltd60 enrolled1 locationACTRN12625001324404
Recruiting
Phase 1Phase 2

MSC Exosome Therapy for Post-Preeclampsia Endothelial Dysfunction

PostpartumPreeclampsiaCell Therapy+2 more
Universitas Padjadjaran80 enrolled1 locationNCT07183384
Recruiting
Phase 1Phase 2

Daily Aspirin vs Split Dosing in High-risk Pregnancies (DASH)

PreeclampsiaPreterm Birth
Thomas Jefferson University400 enrolled1 locationNCT06826859
Recruiting
Phase 1

Safety, Tolerability, and PK/PD of Telpegfilgrastim Injection in Non-pregnant Females of Childbearing

Preeclampsia
Xiamen Amoytop Biotech Co., Ltd.30 enrolled1 locationNCT06924385
Recruiting
Phase 1Phase 2

Intravenous Labetalol Versus Hydralazine in Preeclampsia

Preeclampsia Severe
Tanta University40 enrolled1 locationNCT06360601
Recruiting
Phase 1

Pharmacokinetics of broccoli sprout extract in preeclampsia.

Preeclampsia
Monash Health18 enrolled2 locationsACTRN12618001655235
Completed
Phase 1

A pilot study of antenatal maternally administered melatonin to decrease the level of oxidative stress in human pregnancies affected by preeclampsia (PAMPR Trial).

Preeclampsia
Monash Health Research Directorate20 enrolled2 locationsACTRN12613000476730
Completed
Phase 1

Treating early onset severe preeclampsia with pravastatin: an early phase clinical trial

Preeclampsia
The Mercy Hospital for Women12 enrolled1 locationACTRN12613000268741