Phase 2 Premature Clinical Trials

15 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 115 of 15 trials

Recruiting
Phase 2

The Role of Anifrolumab in Improving Markers of Vascular Risk in Patients With Systemic Lupus Erythematosus (SLE) - IFN-CVD

Cardiovascular DiseaseSystemic Lupus ErythematosusPremature Atherosclerosis
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)45 enrolled1 locationNCT05440422
Recruiting
Phase 2

Co-administration of Acetaminophen With Ibuprofen to Improve Duct-Related Outcomes in Extremely Premature Infants

Patent Ductus Arteriosus After Premature Birth
Mount Sinai Hospital, Canada310 enrolled9 locationsNCT05340582
Recruiting
Phase 1Phase 2

PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysplasia

Critical IllnessBronchopulmonary Dysplasia (BPD)Premature Births
Duke University28 enrolled4 locationsNCT07101640
Recruiting
Phase 2

Study to Evaluate the Potential Effects of KH-001 on Intravaginal Ejaculatory Latency Time (IELT), Patient-Reported Outcomes, and Safety in Men With Lifelong Premature Ejaculation (LPE)

Premature Ejaculation
Kadence Bio40 enrolled1 locationNCT07434271
Recruiting
Phase 1Phase 2

PK/PD of Digoxin in Infants With SVHD

Single VentricleInfant ConditionsInfant, Newborn, Diseases+1 more
Duke University20 enrolled2 locationsNCT06613477
Recruiting
Phase 2

Anakinra Pilot 2 - A Study to Optimise Dose and Route of Administration of Anakinra in Preterm Infants

Very premature infantsPremature infantsInflammation
Monash Medical Centre24 enrolled2 locationsNCT07254000
Recruiting
Phase 2

Proof of Concept Study on BP1.4979 Effect on Primary Premature Ejaculation

Premature (Early) Ejaculation
Bioprojet60 enrolled1 locationNCT07047404
Recruiting
Phase 1Phase 2

Clinical Study on the Safety and Efficacy of Human Amniotic Mesenchymal Stem Cells in the Treatment of Premature Ovarian Insufficiency

Premature Ovarian Insufficiency
Yan Hongli50 enrolled1 locationNCT07115082
Recruiting
Phase 1Phase 2

Dose-finding for Dobutamine During Transitional Circulation in Very Preterm Infants

Infant, Premature, DiseasesCirculatory and Respiratory Physiological Phenomena
Instituto de Investigación Hospital Universitario La Paz30 enrolled3 locationsNCT06878742
Recruiting
Phase 2Phase 3

Autologous PRP Infusion May Restore Ovarian Function and May Promote Folliculogenesis in POI Patients

Menopause Related ConditionsPremature Ovarian FailureMenopause, Premature+2 more
Genesis Athens Clinic100 enrolled1 locationNCT04031456
Suspended
Phase 2Phase 3

The Torpido2 Study: Targeted Oxygenation in the Respiratory care of Premature Infants at Delivery: Effects on developmental Outcome

Oxidative stress in premature infantsBronchopulmonary dysplasia in premature infantsResuscitation of premature infants+2 more
University of Sydney1,200 enrolled5 locationsACTRN12615000115538
Not Yet Recruiting
Phase 2

A study of intranasal remifentanil for intubation and surfactant administration in newborns

Pain management for premature infants undergoing intubation.
Associate Professor Ian Wright40 enrolled1 locationACTRN12612000386831
Recruiting
Phase 2Phase 3

The To2rpido Study: Targeted Oxygenation in the Resuscitation of Premature Infants and their Developmental Outcome

Oxidative stress in premature infantsBronchopulmonary dysplasia in premature infantsResuscitation in premature infants+1 more
The Royal Hospital for Women1,892 enrolled1 locationACTRN12610001059055
Recruiting
Phase 2

A randomised trial to see if closing the arterial duct improves outcome in very premature babies

Premature babiesDeath
Dr David Knight90 enrolled2 locationsACTRN12607000532404
Recruiting
Phase 2

Comparison of two methods of continuous positive airway pressure (CPAP) to support successful extubation of infants of birth weights less than or equal to 1500 grams (C2CPAP)

It has been shown that premature infants are successfully extubated using CPAP. This study compares two popular methods of delivering CPAP to determine if one is more successful at supporting extubation in infants less than or equal to 1500 gram infants.
Sunnybrook and Women's College Health Sciences Centre76 enrolled1 locationACTRN12605000400662