Phase 3 Preserved Ejection Fraction Clinical Trials

7 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 17 of 7 trials

Recruiting
Phase 3

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

ObesityHeart Failure With Preserved Ejection FractionHeart Failure With Mildly Reduced Ejection Fraction
Amgen5,056 enrolled596 locationsNCT07037459
Recruiting
Phase 3

Selenium Intervention Registry Randomized Trial in Heart Failure

Heart FailureHeart Failure and Reduced Ejection FractionHeart Failure and Preserved Ejection Fraction+3 more
Skane University Hospital4,326 enrolled11 locationsNCT07543562
Recruiting
Phase 2Phase 3

Tailored Exercise Training Study Among Adults With HFpEF

Diabetic CardiomyopathiesHFpEF - Heart Failure With Preserved Ejection Fraction
University of Texas Southwestern Medical Center120 enrolled1 locationNCT07223242
Recruiting
Phase 2Phase 3

A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction

Diabetes Mellitus, Type 2Heart Failure With Preserved Ejection FractionHeart Failure, Diastolic+2 more
University of Leicester63 enrolled3 locationsNCT05887271
Recruiting
Phase 3

Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction

Heart Failure With Preserved Ejection Fraction
Uppsala University2,000 enrolled78 locationsNCT02901184
Recruiting
Phase 3

A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart Failure

Heart FailureCardiovascular DiseasesHypertension+5 more
Pulnovo Medical (Wuxi) Co., Ltd.264 enrolled1 locationNCT05824923
Completed
Phase 3Phase 4

Use of exercise and medical therapies to improve cardiac function among patients with exertional shortness of breath due to lung congestion

Diastolic dysfunction, heart failure with preserved ejection fraction (HFpEF)
University of Queensland150 enrolled1 locationACTRN12610001087044