Phase 1 Primary Sclerosing Cholangitis Clinical Trials
7 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–7 of 7 trials
Recruiting
Phase 1
A Study of TAK-781 in Healthy Volunteers and in Participants With Non-Cirrhotic Primary Sclerosing Cholangitis (PSC)
Healthy VolunteersPrimary Sclerosing Cholangitis
Takeda134 enrolled1 locationNCT07229911
Recruiting
Phase 1
A Study of SIPLIZUMAB in AILD and LT Patients
Autoimmune HepatitisPrimary Sclerosing CholangitisLiver Transplant Disorder+1 more
Elizabeth C. Verna8 enrolled1 locationNCT06455280
Withdrawn
Phase 1
A Phase 1, First-In-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PVT201 Following Randomized, Double-blind, Placebo-controlled Single Ascending Doses in primary biliary cholangitis/primary sclerosing cholangitis patients.
Primary Biliary CholangitisPrimary Sclerosing Cholangitis
Parvus Therapeutics, Inc.6 enrolled1 locationACTRN12625000683437
Completed
Phase 1
The Relative Oral Bioavailability of a Tablet Formulation vs a Solution of PLN-74809 in Healthy Participants
Primary Sclerosing Cholangitis
Pliant Therapeutics, Inc.24 enrolled1 locationACTRN12620000573954
Completed
Phase 1
Evaluation of the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of PLN-74809
Primary Sclerosing Cholangitis
Pliant Therapeutics, Inc.80 enrolled1 locationACTRN12620000536965
Completed
Phase 1
Pharmacokinetic and safety study of HTD1801 and its components
Primary Sclerosing Cholangitis (PSC)
Clinical Network Services (CNS) Pty Ltd24 enrolled1 locationACTRN12617000031369
Recruiting
Phase 1
Treating Primary Sclerosing Cholangitis and Biliary Atresia With Vancomycin
Primary Sclerosing CholangitisBiliary Atresia
Sacramento Pediatric Gastroenterology200 enrolled1 locationNCT02137668