Phase 1 Prophylaxis Clinical Trials
6 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–6 of 6 trials
Recruiting
Phase 1
A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)
Cytomegalovirus Prophylaxis
Merck Sharp & Dohme LLC40 enrolled18 locationsNCT07199465
Recruiting
Phase 1
Cabotegravir-Hormone PK/PD Interactions for HIV Prevention
HIVProphylaxisInjectable
Johns Hopkins University32 enrolled1 locationNCT07672717
Recruiting
Phase 1
Excretion of Rivaroxaban in Human Breast Milk
VTE (Venous Thromboembolism)PostpartumBreast Milk Collection+3 more
Thomas Jefferson University10 enrolled1 locationNCT06831474
Recruiting
Phase 1
Ph1, Randomized, Double-Blind and Controlled, Dose Escalation and Expansion Study to Assess the Safety and Pharmacokinetics of JST-010 in Healthy Adults
Pre-exposure Prophylaxis Against Pneumonic Plague in Healthy Adults
Just-Evotec Biologics104 enrolled1 locationNCT06943378
Completed
Phase 1
Ala Wai Phase 1 safety and tolerability study with 14 healthy participants
the treatment and prophylaxis of influenza
Clinical Network Services Pty Ltd14 enrolled1 locationACTRN12616001475437
Completed
Phase 1
A first-in-human study to evaluate the safety tolerability and performance of A/California/7/2009 (H1N1)- like vaccine coated Nanopatches in comparison to placebo coated Nanopatches and intramuscular injection of A/California/7/2009 (H1N1)-like vaccine.. Nanopatches will be delivered to skin using the Vaxxas Clinical Applicator Disposable Device (CAPD).
Prophylaxis for H1N1 infection
Vaxxas Pty Ltd60 enrolled1 locationACTRN12616000880448