Phase 3 Prophylaxis Clinical Trials
10 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–10 of 10 trials
Recruiting
Phase 3
A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)
Human Immunodeficiency Virus (HIV)HIV Pre-Exposure Prophylaxis
Merck Sharp & Dohme LLC4,390 enrolled81 locationsNCT07044297
Recruiting
Phase 3
A Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-010)
Human Immunodeficiency Virus (HIV)HIV Pre-Exposure Prophylaxis
Merck Sharp & Dohme LLC4,580 enrolled30 locationsNCT07071623
Recruiting
Phase 3
Study of Lenacapavir as a Once-Yearly Injection for HIV Pre-exposure Prophylaxis (PrEP)
HIV Pre-Exposure Prophylaxis
Gilead Sciences350 enrolled31 locationsNCT07047716
Recruiting
Phase 3
RIVAroxaban Versus Low-molecular Weight Heparin in Patients With Lower Limb Trauma Requiring Brace or CASTing
Venous ThromboembolismPulmonary EmbolismDeep Vein Thrombosis+3 more
University Hospital, Angers1,424 enrolled35 locationsNCT06195540
Recruiting
Phase 3
Apixaban Prophylaxis for Prevention of Left Ventricular Thrombus Following Anterior Myocardial Infarction
left ventricular thrombusAcute Myocardial Infarction of Anterior WallProphylaxis
National Institute of Cardiovascular Diseases, Pakistan472 enrolled1 locationNCT06742567
Recruiting
Phase 3
The Role of Antibiotic Prophylaxis in Lowering Wound Infection Rates Post-Open Repair of Primary Elective Groin Hernias in High-Risk Patients
Groin HerniaAntibiotic ProphylaxisWound Infection
University of Aleppo200 enrolled1 locationNCT06576154
Recruiting
Phase 3
Intermittent Cefoxitin Administration Versus Loading Bolus Followed by Continuous Infusion for the Prevention of Surgical Site Infection in Colorectal Surgery
Colorectal SurgeryAntibiotic Prophylaxis
Poitiers University Hospital2,000 enrolled19 locationsNCT05755789
Completed
Phase 3Phase 4
Proton Pump Inhibitors vs. Histamine-2 REceptor Blockers for Ulcer Prophylaxis Therapy in the Intensive Care Unit
Ulcer prophylaxis
Medical Research Institute of New Zealand26,797 enrolled4 locationsACTRN12616000481471
Not Yet Recruiting
Phase 3
Efficacy of N-Alpha Methyl Histamine versus Propranolol in prevention of miigraine.
migraine prophylaxis
Hospital General deZona 1 Intituto Mexicano del Seguro Social60 enrolled1 locationACTRN12610000126011
Withdrawn
Phase 3
A Phase III Study Comparing Low Dose Cyclosporine, Methotrexate And Prednisone Versus Standard Dose Cyclosporine and Methotrexate As Graft Versus Host Disease Prophylaxis In Myeloblative Allogeneic Stem Cell Transplantation (ALLG BM10 trial). (Incorporating an Open-Label Sub-study Investigating The Use Of Valganciclovir In The Prevention Of Cytomegalovirus Infection In Hematopoietic Stem Cell Transplant Recipients (ML20712))
Prevention Of CytomegalovirusCell Transplant RecipientsProphylaxis In Myeloblative+3 more
Australasian Leukaemia and Lymphoma Group300 enrolled1 locationACTRN12607000347460