Prophylaxis Clinical Trials

3 recruiting

Frequently Asked Questions

Common questions about Prophylaxis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 42 trials

Recruiting
Not Applicable

California MEPS Hub

Substance Use Disorder (SUD)HIV PreventionHepatitis C Virus (HCV)+3 more
University of California, Los Angeles318 enrolled3 locationsNCT07433985
Recruiting
Phase 3

A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)

Human Immunodeficiency Virus (HIV)HIV Pre-Exposure Prophylaxis
Merck Sharp & Dohme LLC4,390 enrolled76 locationsNCT07044297
Recruiting
Phase 1

A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)

Cytomegalovirus Prophylaxis
Merck Sharp & Dohme LLC40 enrolled11 locationsNCT07199465
Recruiting
Phase 3

A Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-010)

Human Immunodeficiency Virus (HIV)HIV Pre-Exposure Prophylaxis
Merck Sharp & Dohme LLC4,580 enrolled29 locationsNCT07071623
Recruiting
Not Applicable

Moon and Sun Brothers: A Community Prevention Intervention (Hermanos de Luna y Sol)

Help-Seeking BehaviorCondomless SexRisky Health Behavior+1 more
San Francisco State University360 enrolled2 locationsNCT07475702
Recruiting

Monitoring of Anti-TFPI in Hemophilia

HemophiliaRebalancing AgentsProphylaxis
Hospices Civils de Lyon11 enrolled2 locationsNCT07101926
Recruiting

Factors Affecting Vaccine Prophylaxis Efficacy in Bone Marrow and Solid Organ Transplant Recipients: Impact on Infection and Mortality Rates

Vaccine Prophylaxis
Fondazione IRCCS Policlinico San Matteo di Pavia200 enrolled1 locationNCT07473999
Recruiting
Not Applicable

PathToScale: The PERSIST Trial

Oral Pre-exposure Prophylaxis (PrEP)Long-acting Injectable Cabotegravir for PrEP
Georgetown University9,900 enrolled1 locationNCT07221747
Recruiting

Post-ERCP Pancreatitis - Prophylactic Measures Implementation Study (PEP-PROMIS)

Pancreatitis, AcuteERCPProphylaxis
Branislav Kuncak1,000 enrolled1 locationNCT07244432
Recruiting
Phase 4

Linezolid or Vancomycin Surgical Site Infection Prophylaxis

General SurgeryAntibiotic Prophylaxis
Assistance Publique Hopitaux De Marseille1,160 enrolled1 locationNCT05571722
Recruiting

A Study to Learn More About the Safety of Damoctocog-alfa-pegol When Used in Routine Medical Care in Korean Participants With Hemophilia A

Hemophilia AProphylaxis of BleedingTreatment of Bleeding
Bayer20 enrolled1 locationNCT06222697
Recruiting
Not Applicable

Impact of Health Education on Knowledge, Attitude and Practice of Post-exposure Prophylaxis

Post Exposure Prophylaxis
Aswan University340 enrolled1 locationNCT07330427
Recruiting

Real World Evidence Study of SYN023 in Children Exposed to Rabies

Rabies Post-exposure Prophylaxis
Synermore Biologics (Suzhou) Co., Ltd.232 enrolled6 locationsNCT07327307
Recruiting
Phase 4

Azithromycin and Ampicillin for Late PPROM

Premature BirthAntibiotic ProphylaxisPrematurity+3 more
Sheba Medical Center311 enrolled1 locationNCT07183462
Recruiting
Not Applicable

Is Valacyclovir Non-inferior to Valganciclovir as CMV and EBV Prophylaxis in Kidney Transplant Recipients? A Single-Center Prospective Randomized Pilot Study

Kidney Transplantation, Cytomegalovirus InfectionsEBV InfectionAntiviral Prophylaxis
National Taiwan University Hospital80 enrolled1 locationNCT07294547
Recruiting
Phase 3

RIVAroxaban Versus Low-molecular Weight Heparin in Patients With Lower Limb Trauma Requiring Brace or CASTing

Venous ThromboembolismPulmonary EmbolismDeep Vein Thrombosis+3 more
University Hospital, Angers1,424 enrolled35 locationsNCT06195540
Recruiting
Not Applicable

Stick2PrEP Cisgender Women and Trans Individuals

HIV PreventionPre-exposure Prophylaxis
Columbia University175 enrolled1 locationNCT05165745
Recruiting
Phase 1

Excretion of Rivaroxaban in Human Breast Milk

VTE (Venous Thromboembolism)PostpartumBreast Milk Collection+3 more
Thomas Jefferson University10 enrolled1 locationNCT06831474
Recruiting
Not Applicable

Case Management Dyad

HIVPre-exposure ProphylaxisCase Management
University of Chicago180 enrolled1 locationNCT06162897
Recruiting
Phase 1

Ph1, Randomized, Double-Blind and Controlled, Dose Escalation and Expansion Study to Assess the Safety and Pharmacokinetics of JST-010 in Healthy Adults

Pre-exposure Prophylaxis Against Pneumonic Plague in Healthy Adults
Just-Evotec Biologics104 enrolled1 locationNCT06943378