Phase 2 Prostate Adenocarcinoma Clinical Trials
36 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 36 trials
Recruiting
Phase 2
PSMA-Directed Para-Aortic Radiation Therapy for Oligorecurrent Prostate Cancer
Prostate CancerProstate AdenocarcinomaHormone Sensitive Prostate Cancer
University of Miami34 enrolled1 locationNCT06392295
Recruiting
Phase 2
A Study of Lower Dose Radiation Therapy for People With Prostate Cancer
Prostate CancerProstate Adenocarcinoma
Memorial Sloan Kettering Cancer Center54 enrolled7 locationsNCT07635238
Recruiting
Phase 2
Cabozantinib and Atezolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer
Castration-Resistant Prostate CarcinomaStage IV Prostate Cancer AJCC v8Stage IVB Prostate Cancer AJCC v8+2 more
University of Utah33 enrolled1 locationNCT05168618
Recruiting
Phase 2
Focal Therapy With Stereotactic Body Radiation Therapy (SBRT) for Patients With a Single Prostate Tumor
Prostate CancerProstate AdenocarcinomaProstatic Neoplasms
National Cancer Institute (NCI)42 enrolled1 locationNCT05616650
Recruiting
Phase 2
Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial
Prostate Adenocarcinoma
Sean Sachdev50 enrolled1 locationNCT06499870
Recruiting
Phase 2
Neoadjuvant Atezolizumab-Based Combination Therapy in Men With Localized Prostate Cancer Prior to Radical Prostatectomy
Prostate CancerProstate AdenocarcinomaLocalized Prostate Cancer
David Oh68 enrolled2 locationsNCT03821246
Recruiting
Phase 2
INSPIRE: INnovative SABR for Prostate Cancer All IREland
Prostate Adenocarcinoma
Cancer Trials Ireland136 enrolled3 locationsNCT07552168
Recruiting
Phase 2
Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells
Stage IV Prostate Cancer AJCC v8Metastatic Prostate Small Cell Neuroendocrine CarcinomaMetastatic Prostate Adenocarcinoma With Neuroendocrine Differentiation+1 more
National Cancer Institute (NCI)30 enrolled13 locationsNCT05691465
Recruiting
Phase 2
Hyperpolarized Pyruvate (13C) MR Imaging in Monitoring Patients With Prostate Cancer on Active Surveillance
Prostate CancerProstate Adenocarcinoma
University of California, San Francisco60 enrolled1 locationNCT03933670
Recruiting
Phase 2
Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial
Prostate Adenocarcinoma
National Cancer Institute (NCI)90 enrolled5 locationsNCT06022822
Recruiting
Phase 2
Intermittent Fasting Using a Fasting-Mimicking Diet to Improve Prostate Cancer Control and Metabolic Outcomes
Prostate Adenocarcinoma
Stephen Freedland138 enrolled3 locationsNCT05832086
Recruiting
Phase 1Phase 2
Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer
Castration-Resistant Prostate CarcinomaStage IVB Prostate Cancer AJCC v8Metastatic Prostate Adenocarcinoma
University of Michigan Rogel Cancer Center20 enrolled3 locationsNCT06616155
Recruiting
Phase 1Phase 2
Abemaciclib Before 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer
Castration-Resistant Prostate CarcinomaStage IV Prostate Cancer AJCC v8Metastatic Castration-resistant Prostate Cancer+4 more
Vadim S Koshkin30 enrolled1 locationNCT05113537
Recruiting
Phase 2
Neoadjuvant Lu-177-PSMA-617 in Patients With High Risk Localized Prostate Cancer Undergoing Radical Prostatectomy
Prostate Adenocarcinoma
Hackensack Meridian Health54 enrolled3 locationsNCT06798558
Recruiting
Phase 2
Androgen Deprivation Therapy (Relugolix) for the Improvement of Diagnostic Imaging (PSMA PET/CT Scan) in Patients With High Risk or Very High Risk Prostate Cancer, The EnrichPSMA Trial
Stage III Prostate Cancer AJCC v8Stage IV Prostate Cancer AJCC v8Prostate Adenocarcinoma+1 more
Mayo Clinic30 enrolled1 locationNCT07025369
Recruiting
Phase 2
Abiraterone and Prednisone or Darolutamide for the Treatment of Advanced Prostate Cancer
Stage III Prostate Cancer AJCC v8Stage IV Prostate Cancer AJCC v8Advanced Prostate Adenocarcinoma
University of California, Davis75 enrolled1 locationNCT06173362
Recruiting
Phase 2
Study of Recurrence-directed Therapy (RDT) With or Without Androgen-Deprivation Therapy (ADT) In Patients With Radio-recurrent Oligo-metastatic Hormone/Castrate Sensitive Prostate Cancer (romCSPC)
Prostate AdenocarcinomaCastration Sensitive Prostate Cancer
Ontario Clinical Oncology Group (OCOG)162 enrolled3 locationsNCT06654336
Recruiting
Phase 2
Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy
Prostate CancerProstate CarcinomaProstate Neoplasm+15 more
Shehzad Basaria, M.D.60 enrolled1 locationNCT06957691
Recruiting
Phase 2
Effects of Relugolix vs Leuprolide on Cardiac Function in Patients With Prostate Cancer
Prostate AdenocarcinomaStage IIB Prostate Cancer AJCC v8Stage IIC Prostate Cancer AJCC v8
Ohio State University Comprehensive Cancer Center70 enrolled1 locationNCT06330805
Recruiting
Phase 2
A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus Placebo for Patients With High-risk Localized Prostate Cancer
Prostate CancerProstate Adenocarcinoma
University of Chicago90 enrolled2 locationsNCT05726292