Phase 1 Pulmonary Arterial Hypertension Clinical Trials
11 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–11 of 11 trials
Recruiting
Phase 1
Study of Intravenous ZMA001 in Healthy Subjects
Pulmonary Arterial Hypertension PAH
National Heart, Lung, and Blood Institute (NHLBI)96 enrolled1 locationNCT05967299
Recruiting
Phase 1Phase 2
A Phase Ⅰb/Ⅱa Clinical Study of IMC-003 Injection for the Treatment of Pulmonary Arterial Hypertension Receiving Background Therapy.
Pulmonary Arterial Hypertension PAH
ImmuneCare Biopharmaceuticals (Shanghai) Co., Ltd.120 enrolled32 locationsNCT07593027
Recruiting
Phase 1Phase 2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Healthy Volunteers, Pulmonary Arterial Hypertension
Novartis Pharmaceuticals232 enrolled85 locationsNCT06649110
Recruiting
Phase 1
A Study Evaluating the Safety and Tolerability of Artesunate in Patients With Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension PAH
Joseph C. Wu15 enrolled1 locationNCT06872112
Not Yet Recruiting
Phase 1
Phase 1, Open-label, Proof-of Concept Study to Evaluate the Effect of SDS089 Nasal Spray on the Pulmonary Vascular Resistance (PVR) from right hand catheterisation of newly diagnosed and untreated Pulmonary Arterial Hypertension (PAH) patients.
Pulmonary Arterial Hypertension
LTR Pharma Ltd6 enrolled1 locationACTRN12626000434392
Recruiting
Phase 1
A Study on the Efficacy and Safety of Empagliflozin in the Treatment of Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension
China National Center for Cardiovascular Diseases72 enrolled1 locationNCT06554301
Recruiting
Phase 1
Safety, Tolerability and Pharmacokinetics Study of L608 in Healthy Adults
Pulmonary Arterial Hypertension
Pharmosa Biopharm Inc.32 enrolled1 locationNCT06429930
Recruiting
Phase 1
A Placebo-controlled, Randomized Clinical Trial to Assess the Safety, Feasibility, and Pharmacokinetics of Microbiota Transplant Therapy With Antibiotic Preconditioning and Fiber Supplementation in Patients With Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension
University of Minnesota24 enrolled1 locationNCT06481852
Not Yet Recruiting
Phase 1
Study to Evaluate the parameters of TRX-248 Transdermal System in Healthy Female Volunteers
Pulmonary Arterial Hypertension
Corsair Pharma, Inc.9 enrolled1 locationACTRN12625000563460
Completed
Phase 1
A Phase 1, Randomised, Double-Blind Placebo-Controlled, First in Human Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Ascending Doses of ANPA-0073 in Healthy Volunteers
Pulmonary Arterial Hypertension
Avance Clinical Pty Ltd96 enrolled1 locationACTRN12621000644864
Completed
Phase 1
A healthy volunteer study evaluating the the safety, tolerability, and pharmacokinetics of RT234
Pulmonary Arterial Hypertension
Clinical Network Services Pty Ltd32 enrolled1 locationACTRN12618001077257