Phase 1 Pulmonary Arterial Hypertension Clinical Trials
8 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–8 of 8 trials
Recruiting
Phase 1
Study of Intravenous ZMA001 in Healthy Subjects
Pulmonary Arterial Hypertension PAH
National Heart, Lung, and Blood Institute (NHLBI)96 enrolled1 locationNCT05967299
Recruiting
Phase 1Phase 2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Healthy Volunteers, Pulmonary Arterial Hypertension
Novartis Pharmaceuticals232 enrolled85 locationsNCT06649110
Recruiting
Phase 1
A Study on the Efficacy and Safety of Empagliflozin in the Treatment of Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension
China National Center for Cardiovascular Diseases72 enrolled1 locationNCT06554301
Recruiting
Phase 1
Safety, Tolerability and Pharmacokinetics Study of L608 in Healthy Adults
Pulmonary Arterial Hypertension
Pharmosa Biopharm Inc.32 enrolled1 locationNCT06429930
Recruiting
Phase 1
A Placebo-controlled, Randomized Clinical Trial to Assess the Safety, Feasibility, and Pharmacokinetics of Microbiota Transplant Therapy With Antibiotic Preconditioning and Fiber Supplementation in Patients With Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension
University of Minnesota24 enrolled1 locationNCT06481852
Not Yet Recruiting
Phase 1
Study to Evaluate the parameters of TRX-248 Transdermal System in Healthy Female Volunteers
Pulmonary Arterial Hypertension
Corsair Pharma, Inc.9 enrolled1 locationACTRN12625000563460
Completed
Phase 1
A Phase 1, Randomised, Double-Blind Placebo-Controlled, First in Human Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Ascending Doses of ANPA-0073 in Healthy Volunteers
Pulmonary Arterial Hypertension
Avance Clinical Pty Ltd96 enrolled1 locationACTRN12621000644864
Completed
Phase 1
A healthy volunteer study evaluating the the safety, tolerability, and pharmacokinetics of RT234
Pulmonary Arterial Hypertension
Clinical Network Services Pty Ltd32 enrolled1 locationACTRN12618001077257