Phase 2 Pulmonary Clinical Trials

152 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 152 trials

Recruiting
Phase 2Phase 3

Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung

Advanced Extrapulmonary Neuroendocrine CarcinomaMetastatic Extrapulmonary Neuroendocrine CarcinomaRecurrent Extrapulmonary Neuroendocrine Carcinoma+1 more
National Cancer Institute (NCI)189 enrolled244 locationsNCT05058651
Recruiting
Phase 2

Spironolactone for Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension
National Institutes of Health Clinical Center (CC)70 enrolled1 locationNCT01712620
Recruiting
Phase 2

A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) With or Without Standard Treatment

Idiopathic Pulmonary Fibrosis
Boehringer Ingelheim71 enrolled47 locationsNCT07036523
Recruiting
Phase 2

A Study in People With Idiopathic Pulmonary Fibrosis to Test Whether Pirfenidone Influences the Amount of BI 1015550 in the Blood

Idiopathic Pulmonary Fibrosis
Boehringer Ingelheim20 enrolled3 locationsNCT06241560
Recruiting
Phase 2

Bactericidal Activity of TBD09 in Combination With Other Drugs in Pulmonary Tuberculosis

Drug Susceptible Pulmonary Tuberculosis
Gates Medical Research Institute150 enrolled13 locationsNCT07525427
Recruiting
Phase 2

A Study to Learn About the Study Medicine (Called PF-07868489) in People With Pulmonary Arterial Hypertension Who Have Previously Participated in a Clinical Study With PF-07868489

Pulmonary Hypertension
Pfizer36 enrolled44 locationsNCT07073820
Recruiting
Phase 2

Effects of IVIG for BPD in Preterm Infant Born at 28 Weeks and Below

Bronchopulmonary Dysplasia
International Peace Maternity and Child Health Hospital29 enrolled1 locationNCT07561125
Recruiting
Phase 1Phase 2

A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

Healthy Volunteers, Pulmonary Arterial Hypertension
Novartis Pharmaceuticals232 enrolled85 locationsNCT06649110
Recruiting
Phase 2

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

Gastric CancerOvarian CancerCholangiocarcinoma+7 more
National Cancer Institute (NCI)320 enrolled1 locationNCT06503146
Recruiting
Phase 2

An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)

Progressive Pulmonary FibrosisIdiopathic Pulmonary Fibrosis (IPF)
Avalyn Pharma Inc.340 enrolled52 locationsNCT06951217
Recruiting
Phase 2

DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers

Neuroendocrine NeoplasmsSmall Cell Lung CarcinomaExtra-pulmonary Neuroendocrine Carcinoma
Boehringer Ingelheim204 enrolled59 locationsNCT05882058
Recruiting
Phase 2

A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis (IPF)
Rein Therapeutics120 enrolled9 locationsNCT06968845
Recruiting
Phase 2

A Study to Explore the Therapeutic Effect of HEC585 on Delaying Forced Vital Capacity (FVC) Decline and Tolerance in Progressive Fibrosing Interstitial Lung Disease (PF-ILD) Patients

Progressive Fibrosing Interstitial Lung Disease (PF-ILD) / Progressive Pulmonary Fibrosis (PPF)
Sunshine Lake Pharma Co., Ltd.110 enrolled1 locationNCT05139719
Recruiting
Phase 2

A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD

Cardiovascular DiseasesFibrosisLung Diseases+3 more
Pulmovant, Inc.20 enrolled1 locationNCT07333183
Recruiting
Phase 2

Advanced Imaging for Pulmonary Fibrosis

Pulmonary Fibrosis
Peter Caravan60 enrolled1 locationNCT06532071
Recruiting
Phase 2

Bactericidal Activity and Safety of Nicotinamide in Combination With Bedaquiline, Pretomanid, and Linezolid in Drug-susceptible Pulmonary Tuberculosis

Drug Susceptible Pulmonary Tuberculosis
Gates Medical Research Institute165 enrolled4 locationsNCT07517445
Recruiting
Phase 1Phase 2

Feasibility of Semaglutide in Advanced Lung Disease

ObesityChronic Obstructive Pulmonary DiseaseInterstitial Lung Disease+2 more
University of Pennsylvania8 enrolled1 locationNCT05746039
Recruiting
Phase 2

Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)

Pulmonary Arterial Hypertension
Merck Sharp & Dohme LLC42 enrolled35 locationsNCT05587712
Recruiting
Phase 2

A Phase IIb Ensifentrine-glycopyrrolate Fixed-dose Combination Dose Ranging Study in Subjects With COPD

Chronic Obstructive Pulmonary Disease
Verona Pharma plc480 enrolled55 locationsNCT07016412
Recruiting
Phase 1Phase 2

Efficacy of Morphine in Reducing the Rate of Early Non-Invasive Ventilation Failure in Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Phase I/IIa

Chronic Obstructive Pulmonary Disease
University Hospital, Grenoble24 enrolled1 locationNCT04427826