Phase 4 Pulmonary Clinical Trials

54 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 54 trials

Recruiting
Phase 4

A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.

Chronic Obstructive Pulmonary Disease
Sanofi218 enrolled58 locationsNCT07053423
Recruiting
Phase 4

Optimized Treatment of Pulmonary Edema or Congestion

Congestive Heart FailurePulmonary EdemaAcute Heart Failure
Rigshospitalet, Denmark1,104 enrolled4 locationsNCT05276219
Recruiting
Phase 4

A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD) and Hyperinflation

Chronic Obstructive Pulmonary DiseaseHyperinflation
AstraZeneca56 enrolled7 locationsNCT07073950
Recruiting
Phase 4

Sotatercept in Pulmonary Arterial Hypertension

Pulmonary Artery Hypertension
University of Alberta27 enrolled1 locationNCT07140484
Recruiting
Phase 4

Clinical Trial to Evaluate the Efficacy and Safety in Concomitant Administration of Macitentan and Dapagliflozin in Patients With Heart Failure With Mildly Reduced and Preserved Ejection Fraction (HFmrEF and HFpEF) and Combined Pre- and Post-capillary Pulmonary Hypertension (CpcPH)

Group 2 Pulmonary HypertensionHFpEFHFmrEF+2 more
Gachon University Gil Medical Center64 enrolled15 locationsNCT07147114
Recruiting
Phase 4

Comparing Hydrocortisone and Prednisolone for Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD)

Chronic Obstructive Pulmonary Disease (COPD)
Copenhagen Respiratory Research2,000 enrolled14 locationsNCT06892210
Recruiting
Phase 4

Molecular Signatures Associated With Response to ICS Treatment in Patients With COPD Stratified by Eosinophil Levels

Chronic Obstructive Pulmonary Disease
Maria Joyera Rodríguez135 enrolled6 locationsNCT06334575
Recruiting
Phase 4

Erector Spinae Block for Thoracic Surgery

Thoracic CancerPulmonary CancerThoracic Neoplasms+2 more
George Washington University70 enrolled1 locationNCT05521789
Recruiting
Phase 4

Remimazolam for Bronchoscopy in High-Risk Patients

Pulmonary NodulePulmonary InfectionPhthisis+2 more
First Affiliated Hospital of Zhejiang University360 enrolled2 locationsNCT07395596
Recruiting
Phase 4

Dopamine vs. Norepinephrine for Hypotension in Neonates With Pulmonary Hypertension (DONE)

Hypotension and ShockPulmonary Hypertension of the Newborn (PPHN)Hypoxemic Respiratory Failure
University of California, Davis30 enrolled1 locationNCT07322133
Recruiting
Phase 4

The Impact of IV Iron on Exercise Capacity and Quality of Life in Pulmonary Hypertension

Pulmonary Hypertension
Ziekenhuis Oost-Limburg306 enrolled7 locationsNCT07359599
Recruiting
Phase 4

A Study of Sotatercept for Patients With Eisenmenger Syndrome or Unrepaired Shunt-Associated Pulmonary Arterial Hypertension Resistant to Vasodilator Therapy

Eisenmenger SyndromePulmonary Arterial Hypertension of Congenital Heart Disease
Kazuya Hosokawa36 enrolled10 locationsNCT07356778
Recruiting
Phase 4

Rehabilitation for Survivors of Out-of-hospital Cardiac Arrest

Cardiopulmonary ResuscitationCardiac ArrestReturn to Work+1 more
Rigshospitalet, Denmark214 enrolled1 locationNCT05173740
Recruiting
Phase 4

Short-term Antibiotic Therapy in Mycobacterium Avium Complex Pulmonary Disease

Mycobacterium Avium Complex Pulmonary Disease
Bin Cao188 enrolled6 locationsNCT07213765
Recruiting
Phase 4

Right Ventricular Compensation With Sotatercept: A Prospective Single Arm Open Label Phase 4 Study to Evaluate the Effects of Sotatercept on Right Ventricular Function in Pulmonary Arterial Hypertension (RECOMPENSE)

Pulmonary Arterial HypertensionPulmonary Arterial Hypertension PAHPulmonary Arterial Hypertension WHO Group I
Amsterdam UMC, location VUmc20 enrolled1 locationNCT06658522
Recruiting
Phase 4

Short-term Bactericidal Effect of Contezolid in MAC-PD

Mycobacterium Avium Complex Pulmonary Disease
Bin Cao188 enrolled3 locationsNCT07084402
Recruiting
Phase 4

Hydroxychloroquine as a Steroid-sparing Agent in Extrapulmonary Sarcoidosis

Sarcoidosis, Pulmonary
Hospices Civils de Lyon140 enrolled21 locationsNCT05841758
Recruiting
Phase 4

Prevention of Recurrence With Cordyceps Sinensis in Mycobacterium Avium Complex Pulmonary Disease

Mycobacterium Avium Complex Pulmonary Disease
Bin Cao300 enrolled6 locationsNCT07174076
Recruiting
Phase 4

inDividual, Targeted thrombosIS Prophylaxis Versus the Standard 'One Size Fits All' Approach in Patients Undergoing Total hIp or Total kNee replaCemenT

Venous ThromboembolismPulmonary EmbolismDeep Vein Thrombosis+1 more
Leiden University Medical Center10,078 enrolled10 locationsNCT06581965
Recruiting
Phase 4

Clinical Surveillance vs. Anticoagulation for Low-risk Patients With Isolated Subsegmental Pulmonary Embolism

Cardiovascular DiseasesVenous ThromboembolismPulmonary Embolism+6 more
Drahomir Aujesky276 enrolled39 locationsNCT04263038