Phase 3 Radiation Clinical Trials
23 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 23 trials
Recruiting
Phase 2Phase 3
PRO-BOOST-LC: Whole-Gland Boost Strategies Versus SBRT Monotherapy in PSMA-Staged Localized and Locally Advanced Prostate Cancer
Prostate Cancer (Adenocarcinoma)Stereotactic Body Radiation Therapy (SBRT)Localized Prostate Cancer+2 more
Affidea Nu-med Center of Oncological DIagnostics and Therapy1,200 enrolled1 locationNCT07426055
Recruiting
Phase 2Phase 3
PRO-BOOST-N: Prostate-First Versus Combined Prostate and Nodal Dose Escalation in PSMA PET-Staged Node-Positive Prostate Cancer
Prostate CancerBrachytherapyStereotactic Body Radiation Therapy (SBRT)+2 more
Affidea Nu-med Center of Oncological DIagnostics and Therapy1,600 enrolled1 locationNCT07426094
Recruiting
Phase 3
Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases
Radiation ToxicityBrain MetastasasesHigh Grade Glioma (III or IV)+4 more
The Netherlands Cancer Institute408 enrolled5 locationsNCT06888817
Recruiting
Phase 3
Lattice Radiation Therapy Versus Conventional Radiation Therapy for the Palliation of Large Tumors
Histopathologically or Cytologically Confirmed Solid Tumor Who Require Palliation Radiation Therapy to a Lesion ≥5cm
University Health Network, Toronto148 enrolled1 locationNCT07444775
Recruiting
Phase 3
18F-FLUC PET/MR in Patients With Brain Mets
Brain MetastasisRadiation TherapyImmunotherapy, Active
University of Wisconsin, Madison30 enrolled1 locationNCT06159335
Recruiting
Phase 3
Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy
Visual ImpairmentRadiation Retinopathy
Jaeb Center for Health Research600 enrolled22 locationsNCT05844982
Recruiting
Phase 3
Neoadjuvant Treatment Modalities in Esophageal Cancer
Esophageal CancerSurgeryChemotherapy Effect+4 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences2,000 enrolled1 locationNCT04821843
Recruiting
Phase 3
Chemoradiotherapy in Esophageal or Esophagogastric Junction Cancer
Esophagus CancerChemotherapy EffectTargeted Therapy+3 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences2,000 enrolled5 locationsNCT04821778
Recruiting
Phase 3
Prevention and Treatment of Radiation-Induced Oral Mucositis in NPC With Houyanqing Oral Liquid
Nasopharyngeal Cancinoma (NPC)Radiation-induced Oral Mucositis
Sun Yat-sen University244 enrolled16 locationsNCT07311772
Recruiting
Phase 3
Modulating the Skin Microbiome to Prevent Radiation Dermatitis in Breast Cancer
Breast CancerSkin MicrobiomeRadiation Dermatitis
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University326 enrolled1 locationNCT07066280
Recruiting
Phase 3
Omitting CTV for Primary Tumor in LS-SCLC
Radiotherapy Side EffectProgressionSCLC, Limited Stage+1 more
Sun Yat-sen University852 enrolled2 locationsNCT07008716
Recruiting
Phase 3
Topical Betamethasone Versus Moisturizer in Preventing Radiation Dermatitis in Large-Breasted Patients Treated in the Prone Position
Breast CancerRadiation Dermatitis
Sunnybrook Health Sciences Centre276 enrolled1 locationNCT06915857
Recruiting
Phase 3
TSH Suppression During Radiotherapy on Thyroid Site to Prevent Iatrogenic Hypothyroidism in Pediatric Cancer Patients
Hypothyroidism; Irradiation
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano68 enrolled1 locationNCT05316922
Recruiting
Phase 2Phase 3
Radiation Cystitis Treated With Pentosan Polysulfate Sodium Trial
Radiation Cystitis
National Taiwan University Hospital72 enrolled1 locationNCT05245591
Recruiting
Phase 3
Medial vs. Entire Supraclavicular Lymph Node Radiation Therapy for Patients With Invasive Breast Cancer
Breast CancerRadiotherapy; ComplicationsEffect of Radiation Therapy
Fudan University1,650 enrolled1 locationNCT05059379
Recruiting
Phase 3
A comparison of two routinely used skin treatments for women with breast cancer undergoing radiation therapy
Acute radiation therapy (RT) skin toxicity and managementBreast Cancer
Western Sydney Local Health District60 enrolled3 locationsACTRN12619000753156
Terminated
Phase 2Phase 3
Does Mepitel Film decrease skin reactions caused by radiation therapy in head and neck cancer patients?
Acute radiation-induced skin reactionsHead and Neck Cancer
Otago University86 enrolled2 locationsACTRN12616000725460
Completed
Phase 3
The effect of Calendula lotion in reducing the severity of radiation induced dermatitis in women undergoing radiotherapy for breast cancer
Radiation induced dermatitis
Dr Michael Penniment178 enrolled1 locationACTRN12613000165785
Completed
Phase 3
Mepitel Film for the prevention of skin ulceration caused by radiation therapy in breast cancer patients.
Acute side effects of radiation therapy for breast cancerBreast cancer patients treated with radiation
University of Otago80 enrolled1 locationACTRN12612000949886
Recruiting
Phase 3
A double-blind randomised controlled trial of a natural oil-based emulsion containing allantoin versus aqueous cream for managing radiation-induced skin reactions in patients with cancer
Radiation-induced skin reactions in patients with cancer
Raymond Chan172 enrolled1 locationACTRN12612000568819