Phase 2 Radiotherapy Clinical Trials

97 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 97 trials

Recruiting
Phase 2

A Study of QL1706 Combined With Chemotherapy Induction on Sequential Immunotherapy Consolidation in Patients With Limited-Stage Small Cell Lung Cancer After Chemoradiotherapy

Consolidation ImmunotherapyChemoradiotherapyLimited-stage Small Cell Lung Cancer (LS-SCLC)+1 more
Shanghai Chest Hospital28 enrolled1 locationNCT07091305
Recruiting
Phase 2

Different-Dose SCRT Plus CAPOX, PD-1 Blockade and IL-2 in LARC

Rectal CancerRadiotherapy
The First Affiliated Hospital with Nanjing Medical University122 enrolled1 locationNCT07646639
Recruiting
Phase 2

Preoperative IMRT With Anlotinib and Penpulimab for Localized Sarcoma (SPARE-01)

Sarcoma,Soft TissueAnlotinibIntensity Modulated Radiotherapy+3 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences30 enrolled1 locationNCT05167994
Recruiting
Phase 2

Timely Integration of Palliative Care in Oncology Care for Patients Referred for Palliative Radiotherapy on Bone Metastases: A Randomized Trial

RadiotherapyBone Metastases in Subjects With Advanced Cancer
Roxanne Gal246 enrolled5 locationsNCT06805396
Recruiting
Phase 2Phase 3

Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer.

Radiotherapy Side EffectNeoadjuvant TherapyChemotherapy+8 more
National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos400 enrolled1 locationNCT06758830
Recruiting
Phase 2

BITS-TO-HCC Study: HAIC+Iparomlimab/Tuvonralimab + Bevacizumab + SBRT for BCLC-C HCC With PVTT and/or Oligometastases

Hepatocellular CarcinomaRadiotherapyImmunotherapy+3 more
Shandong Cancer Hospital and Institute54 enrolled1 locationNCT07062055
Recruiting
Phase 2

Fruquintinib Combined With Sintilimab ± Radiotherapy for Third-line Treatment of Colorectal Cancer With Liver Metastases

Colorectal, CancerRadiotherapyTargeted Therapy+2 more
Shandong Cancer Hospital and Institute62 enrolled1 locationNCT06356584
Recruiting
Phase 2

A Clinical Trial Comparing Low-Dose RT + Targeted Therapy+ Immunotherapy vs Targeted Therapy+ Immunotherapy Alone as Neoadjuvant Therapy in Operable HNSCC Patients.

Head and Neck Squamous Cell CarcinomaTargeted TherapyImmunotherapy+1 more
West China Hospital98 enrolled1 locationNCT07040956
Recruiting
Phase 2

Spatially Fractionated Radiotherapy Combined With Immunotherapy for Advanced Solid Tumors

Lung CancerRadiotherapyImmune Checkpoint Inhibitor+1 more
Tianjin Medical University Cancer Institute and Hospital30 enrolled3 locationsNCT07058948
Recruiting
Phase 2

A Pilot Study Evaluating β-hydroxybutyrate Supplementation Concomitant to Short-Course Radiotherapy Followed by Immunotherapy Combined With CAPEOX Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer

ChemotherapyRectal CancerRadiotherapy+1 more
Tao Zhang25 enrolled1 locationNCT07239466
Recruiting
Phase 2

Pinoxin for the Prevention of Radiation-Induced Skin Injury

Cancer Patients Undergoning Radiotherapy
Fudan University202 enrolled2 locationsNCT07545720
Recruiting
Phase 2

A Phase 2 Study of Radiotherapy-induced Immune Priming to Enhance Elranatamab (Elra) in Relapsed Refractory Multiple Myeloma (RRMM) With Extramedullary Disease (EMD) and Paramedullary Disease (PMD) "PRIME-EMD-PMD"

Relapsed Refractory Multiple Myeloma (RRMM)Extramedullary Disease in Multiple MyelomaPMD+4 more
M.D. Anderson Cancer Center34 enrolled1 locationNCT07382739
Recruiting
Phase 2

Traditional Chinese Medicine Preparation Alleviates Radiotherapy-induced Oral Mucositis in Head and Neck Cancer Patients.

Radiotherapy-induced Oral Mucositis
West China Hospital128 enrolled1 locationNCT07339774
Recruiting
Phase 2

The Efficacy and Safety of the Combination of PD-1 With Chemotherapy and Adaptive Radiotherapy Strategy in the Treatment of Stage III Non-small Cell Lung Cancer Patients

NSCLCSintilimabAdaptive Radiotherapy
The Third Xiangya Hospital of Central South University35 enrolled1 locationNCT07138755
Recruiting
Phase 2

A Biomarker Study in Men With Localized Prostate Cancer Treated With Aglatimagene Besadenovec

Prostate Cancer (Adenocarcinoma)Prostate Cancer Patients Treated by Radiotherapy
Candel Therapeutics, Inc.45 enrolled7 locationsNCT07332000
Recruiting
Phase 2

Concurrent Chemoradiotherapy Combined With Toripalimab and Surufatinib in the Treatment of Limited-Stage Small Cell Lung Cancer

ChemoradiotherapyLimited-stage Small Cell Lung Cancer (LS-SCLC)Toripalimab+1 more
Sun Yat-sen University47 enrolled1 locationNCT06719700
Recruiting
Phase 2

Iparomlimab and Tuvonralimab Plus Hypofractionated Radiotherapy and Chemotherapy for HAHNSCC

Head and Neck CancerRadiotherapyAnti-PD-1/CTLA-4 Antibody
Second Affiliated Hospital, School of Medicine, Zhejiang University27 enrolled1 locationNCT07447570
Recruiting
Phase 2

Phase II Randomized-registry Embedded Study of Lymphoscintigraphy for Oropharyngeal Neoplasms to Enable Risk-adapted Nodal Guidance for Robotic Surgery and/or Radiotherapy (LONE-RANGR2)

Oropharyngeal NeoplasmsRobotic Surgery and/or RadiotherapyLymphoscintigraphy
M.D. Anderson Cancer Center240 enrolled1 locationNCT06167291
Recruiting
Phase 2

Hypofractionated Radiotherapy With a Focal Microboost for High-Risk and Locally Advanced Prostate Cancer

Prostate CancerProstate Cancer Patients Treated by Radiotherapy
Medical University of South Carolina46 enrolled1 locationNCT07325721
Recruiting
Phase 2

Hybrid Arc Palliative Radiation Therapy (HART): A Single Arm Phase II Trial

Palliative RadiotherapyMetastatic Cancer (Different Solid Tumour Types)
University of Vermont Medical Center103 enrolled1 locationNCT06778408