Phase 2 Radiotherapy Clinical Trials

92 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 92 trials

Recruiting
Phase 2

Spatially Fractionated Radiotherapy Combined With Immunotherapy for Advanced Solid Tumors

Lung CancerRadiotherapyImmune Checkpoint Inhibitor+1 more
Tianjin Medical University Cancer Institute and Hospital30 enrolled3 locationsNCT07058948
Recruiting
Phase 2

A Pilot Study Evaluating β-hydroxybutyrate Supplementation Concomitant to Short-Course Radiotherapy Followed by Immunotherapy Combined With CAPEOX Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer

ChemotherapyRectal CancerRadiotherapy+1 more
Tao Zhang25 enrolled1 locationNCT07239466
Recruiting
Phase 2

Pinoxin for the Prevention of Radiation-Induced Skin Injury

Cancer Patients Undergoning Radiotherapy
Fudan University202 enrolled2 locationsNCT07545720
Recruiting
Phase 2

A Phase 2 Study of Radiotherapy-induced Immune Priming to Enhance Elranatamab (Elra) in Relapsed Refractory Multiple Myeloma (RRMM) With Extramedullary Disease (EMD) and Paramedullary Disease (PMD) "PRIME-EMD-PMD"

Relapsed Refractory Multiple Myeloma (RRMM)Extramedullary Disease in Multiple MyelomaPMD+4 more
M.D. Anderson Cancer Center34 enrolled1 locationNCT07382739
Recruiting
Phase 2

BITS-TO-HCC Study: HAIC+Iparomlimab/Tuvonralimab + Bevacizumab + SBRT for BCLC-C HCC With PVTT and/or Oligometastases

Hepatocellular CarcinomaRadiotherapyImmunotherapy+3 more
Shandong Cancer Hospital and Institute54 enrolled1 locationNCT07062055
Recruiting
Phase 2

Traditional Chinese Medicine Preparation Alleviates Radiotherapy-induced Oral Mucositis in Head and Neck Cancer Patients.

Radiotherapy-induced Oral Mucositis
West China Hospital128 enrolled1 locationNCT07339774
Recruiting
Phase 2

The Efficacy and Safety of the Combination of PD-1 With Chemotherapy and Adaptive Radiotherapy Strategy in the Treatment of Stage III Non-small Cell Lung Cancer Patients

NSCLCSintilimabAdaptive Radiotherapy
The Third Xiangya Hospital of Central South University35 enrolled1 locationNCT07138755
Recruiting
Phase 2

A Biomarker Study in Men With Localized Prostate Cancer Treated With Aglatimagene Besadenovec

Prostate Cancer (Adenocarcinoma)Prostate Cancer Patients Treated by Radiotherapy
Candel Therapeutics, Inc.45 enrolled7 locationsNCT07332000
Recruiting
Phase 2

Concurrent Chemoradiotherapy Combined With Toripalimab and Surufatinib in the Treatment of Limited-Stage Small Cell Lung Cancer

ChemoradiotherapyLimited-stage Small Cell Lung Cancer (LS-SCLC)Toripalimab+1 more
Sun Yat-sen University47 enrolled1 locationNCT06719700
Recruiting
Phase 2

Iparomlimab and Tuvonralimab Plus Hypofractionated Radiotherapy and Chemotherapy for HAHNSCC

Head and Neck CancerRadiotherapyAnti-PD-1/CTLA-4 Antibody
Second Affiliated Hospital, School of Medicine, Zhejiang University27 enrolled1 locationNCT07447570
Recruiting
Phase 2

Phase II Randomized-registry Embedded Study of Lymphoscintigraphy for Oropharyngeal Neoplasms to Enable Risk-adapted Nodal Guidance for Robotic Surgery and/or Radiotherapy (LONE-RANGR2)

Oropharyngeal NeoplasmsRobotic Surgery and/or RadiotherapyLymphoscintigraphy
M.D. Anderson Cancer Center240 enrolled1 locationNCT06167291
Recruiting
Phase 2

Hypofractionated Radiotherapy With a Focal Microboost for High-Risk and Locally Advanced Prostate Cancer

Prostate CancerProstate Cancer Patients Treated by Radiotherapy
Medical University of South Carolina46 enrolled1 locationNCT07325721
Recruiting
Phase 2

Hybrid Arc Palliative Radiation Therapy (HART): A Single Arm Phase II Trial

Palliative RadiotherapyMetastatic Cancer (Different Solid Tumour Types)
University of Vermont Medical Center103 enrolled1 locationNCT06778408
Recruiting
Phase 2

A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia

Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands
MeiraGTx, LLC276 enrolled33 locationsNCT05926765
Recruiting
Phase 2

A Phase II Study Assessing Stereotactic Radiotherapy in Therapeutic Strategy of Oligoprogressive Renal Cell Carcinoma Metastases

Metastatic Renal Cell CarcinomaRadiotherapy
Centre Francois Baclesse77 enrolled30 locationsNCT04299646
Recruiting
Phase 1Phase 2

Hypofractionated Radiotherapy Plus Immunochemotherapy for Neoadjuvant Treatment of Gastroesophageal Junction Adenocarcinoma

Gastroesophageal Junction AdenocarcinomaHypofractionated Radiotherapy
West China Hospital84 enrolled4 locationsNCT07182565
Recruiting
Phase 2

Node-Sparing Hypofractionated Radiotherapy Plus Chemotherapy and PD-1 Inhibitor in pMMR/MSS High-Risk Locally Advanced Colon Cancer: A Prospective, Randomized, Phase II Trial

RadiotherapyNeoadjuvant TherapiesImmune Checkpoint Therapy
Sixth Affiliated Hospital, Sun Yat-sen University52 enrolled1 locationNCT07230639
Recruiting
Phase 2

Clinical Study of Thiopegfilgrastim for Preventing Bone Marrow Suppression in Thoracic Tumor Chemoradiotherapy

Thoracic NeoplasmsChemoradiotherapyMyelosuppression
Affiliated Hospital of Nantong University30 enrolled1 locationNCT07205536
Recruiting
Phase 2

SCRT VS LCRT Followed by PD-L1 Inhibitor Plus CAPEOX as TNT in Patients With LARC

Rectal CancerRadiotherapyAdvanced Stage Colorectal Cancer
Shandong Provincial Hospital208 enrolled1 locationNCT07284992
Recruiting
Phase 1Phase 2

Hypofractionated Radiotherapy Combined With Immunochemotherapy for Conversion Treatment of Gastroesophageal Junction Adenocarcinoma

ChemotherapyGastroesophageal Junction AdenocarcinomaImmunotherapy+1 more
West China Hospital88 enrolled4 locationsNCT07072351