Phase 3 Radiotherapy Clinical Trials

37 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 1–20 of 37 trials

Recruiting
Phase 3

Consolidation of Toripalimab and Capecitabine After Chemoradiotherapy in ESCC

Esophageal CancerChemoradiotherapy
Sun Yat-sen University242 enrolled1 locationNCT07177794
Recruiting
Phase 3

CCRT Followed by PD-1 Inhibitor Maintenance Therapy in Locally Advanced ESCC

Esophageal CarcinomaRadiotherapyImmunotherapy
Fudan University452 enrolled1 locationNCT06964568
Recruiting
Phase 3

A Randomized Trial of Five Fraction Partial Breast Irradiation (RAPID2)

Breast Neoplasm FemaleRadiotherapyCosmetic Outcome
Ontario Clinical Oncology Group (OCOG)910 enrolled28 locationsNCT05417516
Recruiting
Phase 3

64Cu-SAR-bisPSMA Positron Emission Tomography: A Phase 3 Study of Participants With Biochemical Recurrence of Prostate Cancer

Prostate CancerCryotherapyProstate Cancer Recurrent+3 more
Clarity Pharmaceuticals Ltd220 enrolled28 locationsNCT06970847
Recruiting
Phase 3

Bevacizumab Plus FSRT Versus Hippocampus-Avoidant WBRT in Lung Adenocarcinoma With Extensive Brain Metastases

Brain MetastasesLung AdenocarcinomaWhole-Brain Radiotherapy+2 more
Sun Yat-sen University220 enrolled3 locationsNCT07481786
Recruiting
Phase 3

IC Plus Low-dose Radiation Plus Cadonilimab in LANPC

ChemotherapyRadiotherapyImmune Checkpoint Inhibitor+1 more
Sun Yat-sen University380 enrolled3 locationsNCT05941741
Recruiting
Phase 3

Flap Sparing in Postoperative Radiotherapy of Oral Cavity Cancers

Radiotherapy, AdjuvantOral Cavity CarcinomaFlap+1 more
Centre Francois Baclesse348 enrolled25 locationsNCT06798922
Recruiting
Phase 3

Anlotinib Plus Whole-Brain Radiotherapy for Brain Metastases in SCLC Patients.

Whole-Brain Radiotherapy
Cancer Institute and Hospital, Chinese Academy of Medical Sciences134 enrolled1 locationNCT07443397
Recruiting
Phase 3

Is Adaptive SBRT for Prostate vs Image-guided Radiotherapy a True Evolution (ASPIRE)

Stereotactic Body RadiotherapyLocalized Prostate Cancer
University Health Network, Toronto320 enrolled1 locationNCT06825091
Recruiting
Phase 3

TDLN-sparing RT Plus Immunotherapy and Chemotherapy in Locally Advanced ESCC

Esophageal CarcinomaRadiotherapyImmunotherapy
Fudan University432 enrolled1 locationNCT06676449
Recruiting
Phase 3

Adjuvant Radiotherapy of Sintilimab Versus TACE for HCC

Radiotherapy, AdjuvantHepatocellular Carcinoma (HCC)Immune Checkpoint Inhibitor+2 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences286 enrolled1 locationNCT07186621
Recruiting
Phase 2Phase 3

Node-Sparing Short-Course Radiotherapy Plus Chemotherapy, Bevacizumab and PD-1 Inhibitor in Metastatic pMMR/MSS Colorectal Cancer (MODIFI-CRC)

RadiotherapyMetastatic Colorectal Cancer (CRC)Immune Checkpoint Therapy
Sixth Affiliated Hospital, Sun Yat-sen University286 enrolled1 locationNCT06958419
Recruiting
Phase 2Phase 3

Node-Sparing Short-Course Radiotherapy Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer (MODIFI-RC-II)

Rectal CancerRadiotherapyNeoadjuvant Therapies+1 more
Sixth Affiliated Hospital, Sun Yat-sen University430 enrolled1 locationNCT06958432
Recruiting
Phase 3

Continuation of First-line Therapy With Radiotherapy Versus Early Switch to Second-line Therapy in Oligoprogressive HCC

RadiotherapyOligoProgressive Metastatic DiseaseHepatocellular Carcinoma (HCC)+1 more
Shandong Cancer Hospital and Institute132 enrolled1 locationNCT06841172
Recruiting
Phase 3

Neoadjuvant Immunotherapy Plus Chemotherapy Followed by Concurrent Chemoradiotherapy and Consolidative Immunotherapy for Locally Advanced Non-small Cell Lung Cancer

Neoadjuvant TherapyImmunotherapyLocally Advanced Non-Small Cell Lung Cancer+1 more
Sun Yat-sen University497 enrolled1 locationNCT06734702
Recruiting
Phase 3

Personalized Long-course Radiotherapy Plus Chemotherapy With or Without Immunotherapy for LARC: PALACE Study

RadiotherapyImmunotherapyLocally Advanced Rectal Cancer (LARC)+2 more
West China Hospital184 enrolled1 locationNCT07020247
Recruiting
Phase 3

Omitting CTV for Primary Tumor in LS-SCLC

Radiotherapy Side EffectProgressionSCLC, Limited Stage+1 more
Sun Yat-sen University852 enrolled2 locationsNCT07008716
Recruiting
Phase 3

Evaluation of Concomitant Chemo-radiotherapy With Cisplatine vs Gemcitabin in Locally Advanced Cervicouterine Cancer

Locally Advanced Cervical CancerGemcitabineChemo-radiotherapy
National Institute of CancerologĂ­a140 enrolled1 locationNCT06156514
Recruiting
Phase 3

Prophylactic Radiotherapy Optimization for Enhanced Thyroid Function Protection in NPC

Radiotherapy Side EffectQuality of LifeRadiotherapy+2 more
Jiangxi Provincial Cancer Hospital474 enrolled1 locationNCT06752239
Recruiting
Phase 3

Moderated Hypofractionated Online Adaptive Radiotherapy in Cervical Cancer

Cervical CancerAdaptive Radiotherapy
Peking Union Medical College Hospital440 enrolled1 locationNCT06641635