Phase 3 RCT Clinical Trials

31 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 31 trials

Recruiting
Phase 3

Prehospital Pulse-dose Glucocorticoid in Patients With ST-segment Elevation Myocardial Infarction 2 - The PULSE-MI 2 Trial

STEMI - ST Elevation Myocardial Infarction
Thomas Engstrom5,204 enrolled4 locationsNCT07478003
Recruiting
Phase 3

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

Cardiovascular RiskAcute Myocardial Infarction (AMI)
Novo Nordisk A/S10,000 enrolled970 locationsNCT06118281
Recruiting
Phase 3

Effects of Ziltivekimab on Coronary Atherosclerotic Burden in Patients With Acute Myocardial Infarction

Coronary Artery DiseaseAcute Myocardial Infarction (AMI)Coronary Atherosclerosis of Native Coronary Artery
ECRI bv332 enrolled1 locationNCT07276282
Recruiting
Phase 3

Aspirin Continuation or Interruption in Patients at Moderate Risk for Cardiovascular Events Undergoing Colonoscopy and/or Polypectomy

Myocardial Infarction (MI)Cardiovascular EventsPost Polypectomy Bleeding in Antiplatelet Patients
Chinese University of Hong Kong2,514 enrolled1 locationNCT07052799
Recruiting
Phase 3

A Research Study to Look at the Effect of Ziltivekimab on Plaque in the Blood Vessels of the Heart, Compared to Placebo, in People With a Heart Attack

Myocardial Infarction
Novo Nordisk A/S332 enrolled20 locationsNCT07301034
Recruiting
Phase 3

Aspirin-free Strategy With Ticagrelor in Patients With a Myocardial Infarction Treated Medically Alone

Myocardial InfarctionNSTEMI - Non-ST Segment Elevation MISTEMI (ST Elevation MI)
Montreal Heart Institute2,570 enrolled1 locationNCT07257198
Recruiting
Phase 3

Dapagliflozin in STEMI

Myocardial InfarctionST Elevation Myocardial Infarction
Ottawa Heart Institute Research Corporation256 enrolled1 locationNCT06174753
Recruiting
Phase 3

Assessment of an Early De-Escalation to a Low-potency Single Antiplatelet Therapy Guided by Genetics Versus a Systematic High-Potency Single Antiplatelet Therapy to Neutralize Bleeding Complications in Patients With High Bleeding Risk Beyond One Month After an Acute Coronary Syndrome

Myocardial Infarction
Assistance Publique - Hôpitaux de Paris2,468 enrolled1 locationNCT05577988
Recruiting
Phase 3

Efficacy of Montelukast on STEMl Patients

Myocardial Infarction (MI)
Shanghai Zhongshan Hospital512 enrolled12 locationsNCT07320625
Not Yet Recruiting
Phase 3Phase 4

Prevention of Reperfusion Injury in Myocardial Infarction II - PRIME II

Myocardial Infarction
Te Whatu Ora75 enrolled1 locationACTRN12626000027314
Recruiting
Phase 3

Effect of Glp-1 and Antidiabetic sgLT2 Agents for myoCardial infarcTion and Ultrasensitive Inflammatory Surveillance (GALACTUS Trial)

Acute Myocardial Infarction With ST Elevation
Instituto Mexicano del Seguro Social44 enrolled1 locationNCT07295223
Recruiting
Phase 3

Epicardial Cardiac Fat-CT (EPIC-CT)

Epicardial fatSTEMI - ST Elevation Myocardial Infarction
Instituto Mexicano del Seguro Social136 enrolled1 locationNCT07297589
Recruiting
Phase 3

Early Antiplatelet Administration After Intravenous Thrombolysis for Acute Ischemic Stroke (TREND-IVT)

Acute Ischemic StrokeCerebral Infarction
Capital Medical University1,184 enrolled71 locationsNCT06548971
Recruiting
Phase 3

Remote Ischemic Conditioning for Acute Ischemic Stroke Treated With Mechanical Thrombectomy(RECAST-MT)

Acute Ischemic StrokeAnterior Circulation Brain Infarction
Capital Medical University2,105 enrolled56 locationsNCT06559241
Recruiting
Phase 3

A EUROpean Randomized Study on Blood-thinners and Cholesterol-lowering Treatments to Prevent Future Vascular Events in People With Covert Brain Infarcts (CBI)

Covert Brain Infarction
Aarhus University Hospital1,652 enrolled14 locationsNCT07012629
Recruiting
Phase 3

Methylprednisolone for Stroke With Large Infarct Core and Post-stroke Lymphocytopenia

Large Infarct CorePost-stroke Lymphocytopenia
YiLin200 enrolled1 locationNCT07202143
Recruiting
Phase 3

Evaluation of Low Dose Colchicine and Ticagrelor in Prevention of Ischemic Stroke in Patients With Stroke Due to Atherosclerosis

Stroke, IschemicStrokeAtherosclerosis+5 more
Assistance Publique - Hôpitaux de Paris2,800 enrolled1 locationNCT05476991
Recruiting
Phase 2Phase 3

The Efficacy and Safety of HRS8179 in Severe Cerebral Edema Following Large Hemispheric Infarction

Severe Cerebral Edema Following Large Hemispheric Infarction
Beijing Suncadia Pharmaceuticals Co., Ltd725 enrolled1 locationNCT06732648
Recruiting
Phase 3

A Study of Angiotensin-II Receptor Blocker on Cardiovascular Remodeling (VALUE Trial)

Coarctation of AortaHigh Blood Pressure
Mayo Clinic120 enrolled1 locationNCT06150560
Recruiting
Phase 2Phase 3

Pleiotropic Effects of Dapagliflozin in Patients With Acute Coronary Syndromes

Ventricular DysfunctionDiabetesAcute Coronary Syndrome+1 more
University of Sao Paulo80 enrolled1 locationNCT06286878