Phase 3 Renal Cell Carcinoma Clinical Trials

14 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 114 of 14 trials

Recruiting
Phase 3

Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

Metastatic Clear Cell Renal Cell CarcinomaAdvanced Clear Cell Renal Cell Carcinoma
Arcus Biosciences, Inc.720 enrolled44 locationsNCT07011719
Recruiting
Phase 3

A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)

Renal Cell Carcinoma
Merck Sharp & Dohme LLC904 enrolled103 locationsNCT07227402
Recruiting
Phase 3

Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

Renal Cell Carcinoma (RCC)Clear Cell Renal Cell CarcinomaStage II Renal Pelvis Cancer AJCC v8+1 more
Alliance for Clinical Trials in Oncology1,040 enrolled409 locationsNCT06661720
Recruiting
Phase 3

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Lung Non-Small Cell Carcinoma+7 more
NRG Oncology269 enrolled263 locationsNCT06500455
Recruiting
Phase 3

Phase 3 Study to Assess Safety and Efficacy of 177Lu-TLX250 in Advanced Relapsed or Recurrent ccRCC

Renal Cell Carcinoma (RCC)Clear Cell Renal Cell Cancer (ccRCC)Renal Cell Carcinoma (Kidney Cancer)+3 more
Telix Pharmaceuticals (Innovations) Pty Limited40 enrolled5 locationsNCT07197580
Recruiting
Phase 3

Neoadjuvant of Axitinib Plus PD-1 to Improve Disease Free Survival of Patients With Renal Cell Carcinoma

Renal Cell CarcinomaNeoadjuvant
ZHOU FANGJIAN298 enrolled8 locationsNCT05738694
Recruiting
Phase 3

Systemic Therapy Alone or With Stereotactic Body Radiotherapy for Oligometastatic Kidney Cancer (STROKER Study)

Renal Cell Carcinoma MetastaticRenal Cell Carcinoma (Kidney Cancer)Kidney Cancer Metastatic
Sun Yat-sen University252 enrolled9 locationsNCT06726421
Recruiting
Phase 2Phase 3

DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers

CancerRenal Cell CarcinomaLymphoma+8 more
Cancer Research UK30 enrolled27 locationsNCT05770037
Recruiting
Phase 3

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

Metastatic Renal Cell CarcinomaStage IV Renal Cell Cancer AJCC v8Metastatic Clear Cell Renal Cell Carcinoma
SWOG Cancer Research Network364 enrolled387 locationsNCT04510597
Recruiting
Phase 3

Measuring Oncological Value of Exercise and Statin

Breast CancerMetastatic Breast CancerOvarian Cancer+9 more
Tampere University Hospital240 enrolled1 locationNCT05796973
Recruiting
Phase 3

Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO

Head and Neck CancerRenal Cell CarcinomaLung Cancer Metastatic
UNICANCER646 enrolled40 locationsNCT05078047
Recruiting
Phase 3

A Study of Pazopanib With or Without Abexinostat in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma (RENAVIV)

Renal Cell Carcinoma
Xynomic Pharmaceuticals, Inc.413 enrolled38 locationsNCT03592472
Recruiting
Phase 3

89Zr-TLX250 for PET/CT Imaging of ccRCC - ZIRCON-CP Study

Clear Cell Renal Cell Carcinoma
Telix Pharmaceuticals (Innovations) Pty Limited82 enrolled8 locationsNCT06750419
Recruiting
Phase 3

Renal Adjuvant MultiPle Arm Randomised Trial

Renal Cell Carcinoma
University College, London1,750 enrolled35 locationsNCT03288532