Phase 1 Renal Disease Clinical Trials

9 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 19 of 9 trials

Recruiting
Phase 1

A Clinical Trial of MK-2828 in People With Kidney Disease (MK-2828-006)

End Stage Renal DiseaseRenal ImpairmentChronic Kidney Failure
Merck Sharp & Dohme LLC24 enrolled3 locationsNCT07348237
Recruiting
Phase 1Phase 2

Study to Evaluate the Safety and Efficacy of the GGTA1 KO Thymokidney in Patients With ESRD

Kidney TransplantationXenotransplantationESRD (End-Stage Renal Disease)
United Therapeutics50 enrolled1 locationNCT07224763
Recruiting
Phase 1Phase 2

Study to Evaluate the Safety and Efficacy of the 10 GE Xenokidney in Patients With ESRD

Kidney TransplantationXenotransplantationESRD (End-Stage Renal Disease)
United Therapeutics50 enrolled2 locationsNCT06878560
Recruiting
Phase 1Phase 2

To Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of KN060 in ESRD Dialysis Patients

End-Stage Renal Disease Requiring Haemodialysis
Suzhou Alphamab Co., Ltd.12 enrolled1 locationNCT07201467
Recruiting
Phase 1

AMSC for Reducing Anastomotic Stenosis in Primary Arteriovenous Anastomoses

End Stage Renal Disease
Houssam Farres, M.D.15 enrolled1 locationNCT04392206
Recruiting
Phase 1Phase 2

CRISPR-Edited HLA Donor Kidney Transplant to Reduce Rejection Risk

Kidney FailureEnd Stage Renal DiseaseKidney Tumor+4 more
AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC90 enrolled1 locationNCT07053462
Recruiting
Phase 1Phase 2

Roxadustat's Effect on Heart, Nutrition, and Inflammation in Hemodialysis Patients

Cardiovascular Diseases (CVD)Kidney Failure, ChronicMalnutrition-Inflammation Syndrome+1 more
Mansoura University46 enrolled1 locationNCT06903559
Recruiting
Phase 1Phase 2

Roxadustat for Bone and Neuropsychiatric Aspects in Hemodialysis Patients

Depression Anxiety DisorderKidney Failure, ChronicAnemia in End Stage Renal Disease
Mansoura University46 enrolled1 locationNCT06917950
Recruiting
Phase 1Phase 2

The Effect of Gum Arabic (GA) on Residual Renal Function in Adult Dialysis Patients in Abu Dhabi

End Stage Renal Disease (ESRD)
Abu Dhabi Health Services Company40 enrolled1 locationNCT06836206