Phase 2 Retinitis Pigmentosa Clinical Trials

11 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 111 of 11 trials

Recruiting
Phase 2

A Phase II Study of Intravitreal KIO-301 in Patients With Late-stage Retinitis Pigmentosa

Retinitis Pigmentosa
Kiora Pharmaceuticals, Inc.36 enrolled5 locationsNCT06628947
Recruiting
Phase 1Phase 2

A Study to Investigate the Safety of DSP-3077 After a Unilateral Eye Injection in Male and Female Participants 18 Years of Age or Older With Retinitis Pigmentosa

Retinitis Pigmentosa
Sumitomo Pharma America, Inc.12 enrolled2 locationsNCT06891885
Recruiting
Phase 2

Safety of a Single, Intravitreal Injection of 6.0M jCell (Famzeretcel) in Retinitis Pigmentosa (RP)

Retinitis Pigmentosa
jCyte, Inc60 enrolled14 locationsNCT06912633
Recruiting
Phase 2

A Phase 2 Open-label Study to Evaluate the Safety of Laruparetigene Zovaparvovec Administered Bilaterally in Male Participants With X-Linked Retinitis Pigmentosa

X-Linked Retinitis Pigmentosa (XLRP)
Beacon Therapeutics10 enrolled6 locationsNCT07174726
Recruiting
Phase 1Phase 2

A Phase 1/2 Study in Healthy Volunteers and Participants With Autosomal Dominant Retinitis Pigmentosa (RHO-adRP)

Retinitis Pigmentosa
Octant, Inc.50 enrolled1 locationNCT07408232
Recruiting
Phase 1Phase 2

BS01 in Patients With Retinitis Pigmentosa

Retinitis Pigmentosa
Bionic Sight LLC20 enrolled1 locationNCT04278131
Recruiting
Phase 1Phase 2

A Repeat-Dose, Open-Label, Two Arm Safety and Efficacy Study of Two Doses of VP-001 Administered Intravitreally in Participants With Confirmed PRPF31 Mutation-Associated Retinal Dystrophy, Including Participants Previously Treated With VP001

Retinal DegenerationRetinal DiseaseRetinal Dystrophies+2 more
PYC Therapeutics16 enrolled6 locationsNCT06852963
Recruiting
Phase 1Phase 2

A Phase I/II Dose-escalating Study of the Safety, Tolerability and Efficacy of KIO-301 Administered Intravitreally to Patients With Retinitis Pigmentosa and Choroideremia (ABACUS)

Retinitis PigmentosaChoroideremiaNon-Syndromic Rod-Dominant Inherited Retinal Diseases
Kiora Pharmaceuticals, Inc.48 enrolled3 locationsNCT05282953
Recruiting
Phase 1Phase 2

Promising ROd-cone DYstrophy Gene therapY

Retinitis Pigmentosa
SparingVision33 enrolled6 locationsNCT05748873
Recruiting
Phase 1Phase 2

Safety and Efficacy of Stem Cell Small Extracellular Vesicles in Patients With Retinitis Pigmentosa

Retinitis Pigmentosa
Mahidol University15 enrolled1 locationNCT06242379
Recruiting
Phase 1Phase 2

Gene Therapy for RPGR Gene Mutation-associated X-linked Retinitis Pigmentosa

X-Linked Retinitis Pigmentosa (XLRP)
Frontera Therapeutics32 enrolled1 locationNCT06492850