Phase 2 Retinopathy Clinical Trials

15 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 115 of 15 trials

Recruiting
Phase 2

Sleep, Diabetic Retinopathy and Melatonin

Diabetes MellitusDiabetic Retinopathy
University of Illinois at Chicago42 enrolled1 locationNCT04547439
Recruiting
Phase 1Phase 2

Oral Metformin for Treatment of ABCA4 Retinopathy

Retinal DegenerationRetinal DystrophyStargardt Disease+1 more
National Eye Institute (NEI)56 enrolled2 locationsNCT04545736
Recruiting
Phase 2

Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel Dilation

Normal Tension Glaucoma (NTG)Non-proliferative Diabetic Retinopathy (NPDR)Open-angle Glaucoma (OAG)
Qlaris Bio, Inc.14 enrolled1 locationNCT07354477
Recruiting
Phase 2

A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy

Diabetic Retinopathy
Boehringer Ingelheim178 enrolled89 locationsNCT06321302
Recruiting
Phase 2

Safety and Proof of Concept Study of ANXV (Annexin A5) in Patients With Diabetic Retinopathy or Retinal Vein Occlusion

Non-Proliferative Diabetic RetinopathyRetinal Vein Occlusion
Annexin Pharmaceuticals AB12 enrolled1 locationNCT07259928
Recruiting
Phase 2

Effect of Levosulpiride on Retinal Alterations in Patients With Diabetic Retinopathy and Diabetic Macular Edema

Diabetic RetinopathyDiabetic Macular Edema
Carmen Clapp120 enrolled2 locationsNCT03161652
Recruiting
Phase 2

A Study to Evaluate the Efficacy and Safety of Orally Administered VX-01

Diabetic RetinopathyNPDR - Non Proliferative Diabetic Retinopathy
Vantage Biosciences Ltd100 enrolled26 locationsNCT06770933
Recruiting
Phase 2

Intravitreal Topotecan in the Repair of Rhegmatogenous Retinal Detachment with Proliferative Vitreoretinopathy

Proliferative Vitreoretinopathy in Rhegmatogenous Retinal Detachment
Unity Health Toronto50 enrolled2 locationsNCT05523869
Recruiting
Phase 2

Oral Propranolol for Prevention of Threshold Retinopathy of Prematurity

Retinopathy of Prematurity
University of Zurich276 enrolled3 locationsNCT03083431
Recruiting
Phase 2

Prevention of ProliFerative Vitreoretinopathy with Intravitreal MethotreXate in Primary Retinal DEtachment Repair (FIXER) Trial

Proliferative Vitreoretinopathy
Cincinnati Eye Institute, Southwest Ohio860 enrolled1 locationNCT06541574
Recruiting
Phase 2Phase 3

Antiangiogenic Therapy With Bevacizumab in Retinopathy of Prematurity. Structural Outcome

Retinopathy of Prematurity
Asociación para Evitar la Ceguera en México1 locationNCT00346814
Not Yet Recruiting
Phase 2

The effect of tocotrienol-rich vitamin E (Tocovid Suprabio) compared to tocopherol on diabetic microvascular complications: A double-blinded placebo controlled, multicentre clinical trial

Diabetes MellitusDiabetic RetinopathyDiabetic Nephropathy+1 more
Monash University Malaysia200 enrolled2 locationsACTRN12621001268831
Recruiting
Phase 2

The Effects of Tocotrienol-Rich Vitamin E (Tocovid) on Diabetes and Diabetic Microvascular Complications: Kidney Disease (Nephropathy), Eye Disease (Retinopathy) and (Nerve Impariment (Neuropathy)

Diabetes MellitusDiabetic RetinopathyDiabetic Nephropathy+1 more
Monash University Malaysia116 enrolled2 locationsACTRN12619001568101
Suspended
Phase 2Phase 3

The Torpido2 Study: Targeted Oxygenation in the Respiratory care of Premature Infants at Delivery: Effects on developmental Outcome

Oxidative stress in premature infantsBronchopulmonary dysplasia in premature infantsResuscitation of premature infants+2 more
University of Sydney1,200 enrolled5 locationsACTRN12615000115538
Recruiting
Phase 2

A phase II, 12 month, randomized, sham-controlled trial of ranibizumab (Lucentis) combined with grid laser compared with laser alone for the treatment of recalcitrant, diabetic macular oedema.

Diabetic RetinopathyDiabetic Macular Oedema
Novartis40 enrolled1 locationACTRN12611000063910