Phase 2 Retinopathy Clinical Trials
19 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–19 of 19 trials
Recruiting
Phase 2Phase 3
Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular Edema
Diabetic Retinopathy
AbbVie576 enrolled6 locationsNCT07592273
Recruiting
Phase 2
A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants
Intraventricular hemorrhageChronic lung disease of prematurityBronchopulmonary Dysplasia+1 more
OHB Neonatology Ltd.338 enrolled72 locationsNCT03253263
Recruiting
Phase 1Phase 2
Oral Metformin for Treatment of ABCA4 Retinopathy
Retinal DegenerationRetinal DystrophyStargardt Disease+1 more
National Eye Institute (NEI)56 enrolled2 locationsNCT04545736
Recruiting
Phase 2
Oral Propranolol for Prevention of Threshold Retinopathy of Prematurity
Retinopathy of Prematurity
University of Zurich276 enrolled3 locationsNCT03083431
Recruiting
Phase 2
Sleep, Diabetic Retinopathy and Melatonin
Diabetes MellitusDiabetic Retinopathy
University of Illinois at Chicago42 enrolled1 locationNCT04547439
Recruiting
Phase 2
Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel Dilation
Normal Tension Glaucoma (NTG)Non-proliferative Diabetic Retinopathy (NPDR)Open-angle Glaucoma (OAG)
Qlaris Bio, Inc.14 enrolled1 locationNCT07354477
Recruiting
Phase 2
A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy
Diabetic Retinopathy
Boehringer Ingelheim178 enrolled89 locationsNCT06321302
Recruiting
Phase 2
Safety and Proof of Concept Study of ANXV (Annexin A5) in Patients With Diabetic Retinopathy or Retinal Vein Occlusion
Non-Proliferative Diabetic RetinopathyRetinal Vein Occlusion
Annexin Pharmaceuticals AB12 enrolled1 locationNCT07259928
Recruiting
Phase 2
Effect of Levosulpiride on Retinal Alterations in Patients With Diabetic Retinopathy and Diabetic Macular Edema
Diabetic RetinopathyDiabetic Macular Edema
Carmen Clapp120 enrolled2 locationsNCT03161652
Recruiting
Phase 1Phase 2
Topical Netarsudil for the Prevention of Proliferative Vitreoretinopathy in Patients With Retinal Detachment
rhegmatogenous retinal detachmentProliferative Vitreoretinopathy
Massachusetts Eye and Ear Infirmary48 enrolled1 locationNCT06033703
Recruiting
Phase 2
A Study to Evaluate the Efficacy and Safety of Orally Administered VX-01
Diabetic RetinopathyNPDR - Non Proliferative Diabetic Retinopathy
Vantage Biosciences Ltd100 enrolled26 locationsNCT06770933
Recruiting
Phase 1Phase 2
Evaluating a New Peptide Therapy for Retinal Diseases: AMD, Diabetic Retinopathy, and Dystrophies
Retinitis pigmentosa (RP)Age-Related Macular DegenerationDiabetic Retinopathy
Ace Cells Lab Limited100 enrolled2 locationsNCT06787482
Recruiting
Phase 2
Intravitreal Topotecan in the Repair of Rhegmatogenous Retinal Detachment with Proliferative Vitreoretinopathy
Proliferative Vitreoretinopathy in Rhegmatogenous Retinal Detachment
Unity Health Toronto50 enrolled2 locationsNCT05523869
Recruiting
Phase 2
Prevention of ProliFerative Vitreoretinopathy with Intravitreal MethotreXate in Primary Retinal DEtachment Repair (FIXER) Trial
rhegmatogenous retinal detachmentProliferative Vitreoretinopathy
Cincinnati Eye Institute, Southwest Ohio860 enrolled1 locationNCT06541574
Recruiting
Phase 2Phase 3
Antiangiogenic Therapy With Bevacizumab in Retinopathy of Prematurity. Structural Outcome
Retinopathy of Prematurity
Asociación para Evitar la Ceguera en México1 locationNCT00346814
Not Yet Recruiting
Phase 2
The effect of tocotrienol-rich vitamin E (Tocovid Suprabio) compared to tocopherol on diabetic microvascular complications: A double-blinded placebo controlled, multicentre clinical trial
Diabetes MellitusDiabetic RetinopathyDiabetic Nephropathy+1 more
Monash University Malaysia200 enrolled2 locationsACTRN12621001268831
Recruiting
Phase 2
The Effects of Tocotrienol-Rich Vitamin E (Tocovid) on Diabetes and Diabetic Microvascular Complications: Kidney Disease (Nephropathy), Eye Disease (Retinopathy) and (Nerve Impariment (Neuropathy)
Diabetes MellitusDiabetic RetinopathyDiabetic Nephropathy+1 more
Monash University Malaysia116 enrolled2 locationsACTRN12619001568101
Suspended
Phase 2Phase 3
The Torpido2 Study: Targeted Oxygenation in the Respiratory care of Premature Infants at Delivery: Effects on developmental Outcome
Oxidative stress in premature infantsBronchopulmonary dysplasia in premature infantsResuscitation of premature infants+2 more
University of Sydney1,200 enrolled5 locationsACTRN12615000115538
Recruiting
Phase 2
A phase II, 12 month, randomized, sham-controlled trial of ranibizumab (Lucentis) combined with grid laser compared with laser alone for the treatment of recalcitrant, diabetic macular oedema.
Diabetic RetinopathyDiabetic Macular Oedema
Novartis40 enrolled1 locationACTRN12611000063910