Phase 3 Retinopathy Clinical Trials

12 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 112 of 12 trials

Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of OTX-TKI (Axitinib Implant) in Participants With Non-Proliferative Diabetic Retinopathy

Non-Proliferative Diabetic Retinopathy
Ocular Therapeutix, Inc.930 enrolled1 locationNCT07235085
Recruiting
Phase 3

Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR

Proliferative Diabetic Retinopathy (PDR)
Jaeb Center for Health Research426 enrolled20 locationsNCT06790784
Recruiting
Phase 3

Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy

Visual ImpairmentRadiation Retinopathy
Jaeb Center for Health Research600 enrolled22 locationsNCT05844982
Recruiting
Phase 3

Fenofibrate for Prevention of DR Worsening

Diabetic Retinopathy
Jaeb Center for Health Research560 enrolled66 locationsNCT04661358
Recruiting
Phase 3

Clinical Study on the Efficacy and Safety of TNTL in the Treatment of Non-proliferative Diabetic Retinopathy

Non-Proliferative Diabetic Retinopathy
Beletalent (Zhuhai) Pharmaceutical Co., Ltd360 enrolled30 locationsNCT06817265
Recruiting
Phase 3

A Efficacy and Safety Study of Ranibizumab 10mg/ml Injection (Incepta) in Patients With Diabetic Macular Edema

Retinal DegenerationMacular DegenerationDiabetic Retinopathy+3 more
Incepta Pharmaceuticals Ltd70 enrolled1 locationNCT06305416
Recruiting
Phase 3

Intranasal Dexmedetomidine for Pain Management During Screening for Retinopathy of Prematurity

Retinopathy of PrematurityDexmedetomidine
Assaf-Harofeh Medical Center30 enrolled1 locationNCT06067958
Recruiting
Phase 2Phase 3

Antiangiogenic Therapy With Bevacizumab in Retinopathy of Prematurity. Structural Outcome

Retinopathy of Prematurity
Asociación para Evitar la Ceguera en México1 locationNCT00346814
Recruiting
Phase 3

Steroid Eye Drops in Chronic Central Serous Chorioretinopathy

Chronic Central Serous Chorioretinopathy
Radboud University Medical Center40 enrolled2 locationsNCT05633576
Suspended
Phase 2Phase 3

The Torpido2 Study: Targeted Oxygenation in the Respiratory care of Premature Infants at Delivery: Effects on developmental Outcome

Oxidative stress in premature infantsBronchopulmonary dysplasia in premature infantsResuscitation of premature infants+2 more
University of Sydney1,200 enrolled5 locationsACTRN12615000115538
Active
Phase 3

The Fenofibrate And Microvascular Events in Type 1 diabetes Eye: A randomised trial to evaluate the efficacy on retinopathy and safety of fenofibrate in adults with type 1 diabete. A multicentre double-blind placebo-controlled study in Australia and internationally

Eye disease (retinopathy) in type 1 diabetes mellitusDiabetic nephropathy in type 1 diabetes mellitus
NHMRC Clinical Trials Centre, University of Sydney450 enrolled23 locationsACTRN12611000249954
Recruiting
Phase 3

Efficacy of intravitreal triamcinolone acetonide before pan retinal photocoagulation for improvement of visual acuity and macular edema in diabetic retinopathy

Diabetic macular edema in severe non proliferative diabetic retinopathy (NPDR)or proliferative diabetic retinopathy(PDR)
Eye Research Center, Farabi Eye Hospital60 enrolled1 locationACTRN12607000225415